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  • Ovid Technologies (Wolters Kluwer Health)  (5)
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  • Ovid Technologies (Wolters Kluwer Health)  (5)
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  • 1
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2011
    In:  Otology & Neurotology Vol. 32, No. 9 ( 2011-12), p. 1486-1491
    In: Otology & Neurotology, Ovid Technologies (Wolters Kluwer Health), Vol. 32, No. 9 ( 2011-12), p. 1486-1491
    Type of Medium: Online Resource
    ISSN: 1531-7129
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2011
    detail.hit.zdb_id: 2058738-7
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  • 2
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Otology & Neurotology Vol. 42, No. 2 ( 2021-02), p. e161-e167
    In: Otology & Neurotology, Ovid Technologies (Wolters Kluwer Health), Vol. 42, No. 2 ( 2021-02), p. e161-e167
    Abstract: We suggest a simple measurement, called the “basal turn–facial ridge (BT–FR) angle,” for determining the electrode insertion axis using preoperative temporal bone computed tomography (CT) to predict hearing preservation (HP) in cochlear implantation (CI). Study Design: Retrospective chart review. Setting: Tertiary referral center. Patients: Eighty-two ears that underwent CI between 2010 and 2018 were included. Ears with preoperative thresholds less than or equal to 80 dB HL at 125, 250, and 500 Hz were enrolled and grouped using the criteria of Skarżyński et al.: Group 1, complete or partial HP; Group 2, minimal HP or complete hearing loss. Intervention: All subjects underwent CI with soft surgery techniques through the round window approach. Main Outcome Measures: The BT–FR angle is the angle between the basal turn line (BT-line), which is a straight line passing through the center of the longitudinal axis of the BT, and the facial ridge line, which is a straight line running from the endpoint of the BT-line to a point just above the facial ridge. Results: The BT–FR angle was 2.5 ± 2.9 degrees in Group 1 and –0.3 ± 2.7 degrees in Group 2 ( p  = 0.003). The angle and hearing loss showed a significant negative correlation ( r  = –0.401, p  = 0.002). In multiple linear regression, “age at operation” ( β coefficient 0.260; p  = 0.001) and the “BT–FR angle” (–1.967; p  = 0.001) were significant variables affecting the degree of residual hearing loss. Conclusions: The BT–FR angle, which can be measured simply, may be useful to predict residual HP after CI.
    Type of Medium: Online Resource
    ISSN: 1531-7129 , 1537-4505
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
    detail.hit.zdb_id: 2058738-7
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  • 3
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Ear & Hearing Vol. 42, No. 4 ( 2021-07), p. 1054-1061
    In: Ear & Hearing, Ovid Technologies (Wolters Kluwer Health), Vol. 42, No. 4 ( 2021-07), p. 1054-1061
    Abstract: The education and school life of children who have undergone cochlear implantation (CI) is very important and should be monitored continuously. This study assessed auditory performance in children with cochlear implants over time, along with educational placement and peer relationship, and compared the results based on the age at CI and the presence of additional disabilities. Design: In total, 77 children who had undergone CI at the Hearing Center in Ajou University Hospital at less than 10 years old and who were presently attending school or had already graduated from school within 3 years were enrolled in this study. All children had congenital bilateral severe or profound hearing loss at the diagnosis. They were classified based on the age at which they received CI: the “early-implanted group,” younger than 3.5 years (n = 38), and the “late-implanted group,” between 3.5 and 10 years old (n = 39). Results: The early-implanted group had worse short-term auditory performance than the late group, but after 2 years of the implant use, auditory performance was similar in both groups. The early and late groups did not differ significantly in terms of the proportions of children who were enrolled in a regular school (94.7% and 89.7%, respectively). However, the early-implanted group had a larger proportion of children who were enrolled in a regular school without additional needs (73.0%), compared with the late group (48.6%) ( p = .034). Children with multiple disabilities showed poorer performance (word score of 57.7% and sentence score of 44.7%) than children with hearing disability only (91.8% and 87.2%, respectively), which affected full-time enrollment in regular schools. With regard to peer relationships, 19.0% of children in the early-implanted group required close observation and assistance, and 9.5% even required help and counseling. Children who underwent early CI had a high tendency toward social restraint, apathy, and over-commitment. No correlations were observed between audiological factors and the aspects of peer relationships assessed in this study. Conclusions: Early CI and the absence of other disabilities were the two main factors that increased the likelihood of full-time enrollment in mainstream classes at regular schools. Nevertheless, many children who underwent earlier CI still encountered difficulties in peer relationships.
    Type of Medium: Online Resource
    ISSN: 1538-4667
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
    detail.hit.zdb_id: 2081799-X
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  • 4
    In: Neurology, Ovid Technologies (Wolters Kluwer Health)
    Abstract: Chromosome 9 open reading frame 72 ( C9orf72 ) gene mutations have been typically associated with frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), but recent studies suggest their involvement in other disorders. This report describes a family with an autosomal dominant pattern of inheritance of progressive verbal auditory agnosia due to GGGGCC repeat expansion in C9orf72. A 60-year-old right-handed male truck driver presented with slowly progressive poor speech perception for 8 years, which became most troublesome when receiving verbal orders over the phone. He had difficulty recognizing single-syllable spoken words beyond his hearing loss, but had no problem understanding complex written language. He had a heterozygous pathogenic variant carrying 160 hexanucleotide repeats in the C9orf72 gene. His family history included his deceased mother with similar symptoms that had progressed over 30 years, as well as his older brother and youngest sister who experienced speech perception difficulty beginning in their early fifties. His asymptomatic younger brother had a heterozygous 2 repeat in the C9orf72 gene, while his symptomatic youngest sister had a heterozygous 159 repeat. The patient and his sister exhibited more pronounced cortical thinning in the frontotemporoparietal areas. The discrepancy observed between the distribution of atrophy and the presentation of symptoms in patients with C9orf72 pathogenic repeat expansion may be attributable to the slow progression of their clinical course over time. The variable symptom presentation of C9orf72 pathogenic repeat expansion highlights the importance of considering this mutation as a potential cause of autosomal dominant degenerative brain diseases beyond FTD and ALS.
    Type of Medium: Online Resource
    ISSN: 0028-3878 , 1526-632X
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2023
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  • 5
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2013
    In:  Otology & Neurotology Vol. 34, No. 4 ( 2013-06), p. 736-742
    In: Otology & Neurotology, Ovid Technologies (Wolters Kluwer Health), Vol. 34, No. 4 ( 2013-06), p. 736-742
    Type of Medium: Online Resource
    ISSN: 1531-7129
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2013
    detail.hit.zdb_id: 2058738-7
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