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  • Nepal Journals Online (JOL)  (2)
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  • Nepal Journals Online (JOL)  (2)
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  • 1
    Online Resource
    Online Resource
    A two year retrospective study of cytohistopathological correlation of cervical smear in a tertiary care hospital
    Nepal Journals Online (JOL) ; 2021
    In:  Asian Journal of Medical Sciences Vol. 12, No. 8 ( 2021-07-30), p. 144-148
    Details
    In: Asian Journal of Medical Sciences, Nepal Journals Online (JOL), Vol. 12, No. 8 ( 2021-07-30), p. 144-148
    Abstract: Background: Cervical cancer in women is the second most common cancer and the commonest cause of mortality in developing countries. The introduction of Pap smear test changed the scenario of cervical cancer with an intense drop in the incidence and mortality due to invasive cervical cancer. Aims and Objective: To evaluate the patterns of cervical smear cytology and to correlate the cervical smear diagnosis with histopathological diagnosis and to assess the efficacy of Pap smears in diagnosing cervical lesions. Materials and Methods: This two-year retrospective study (January 2018 to December 2019) was done in the department of Pathology in a tertiary care hospital. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were calculated considering histopathological diagnosis of cervical biopsy as the gold standard. Results: A total of 316 Pap smears were studied, out of which we selected 154 cases who also undergone biopsy or hysterectomy. Epithelial cell abnormalities (ECA) were found in 28 cases (18.2%). Among this the most common ECA was Atypical squamous cells of undetermined significance (ASCUS) seen in 10 cases (6.5%) followed by LSIL (5.2%), HSIL (3.2%) and SCC of cervix (3.2%). The overall correlation between cervical cytology and histopathology was found in 125 out of 154 cases (81.16%). The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of pap smear was 90.57%, 62.50%, 95.41%, 43.47% and 87.66% respectively. Conclusion: Pap smear is a simple, safe, non-invasive and effective method for detection of lesions of the cervix and ECA. Hence, better awareness and periodical cytological screening programs can help in the early detection of malignant cervical lesions and thereby reducing the morbidity and mortality related to this malignancy.
    Type of Medium: Online Resource
    ISSN: 2091-0576 , 2467-9100
    URL: Article
    DOI: 10.3126/ajms.v12i8.36940
    Language: Unknown
    Publisher: Nepal Journals Online (JOL)
    Publication Date: 2021
    detail.hit.zdb_id: 2894889-0
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Evaluation of Aerosol Contamination during Ultrasonic Procedures
    Nepal Journals Online (JOL) ; 2017
    In:  Journal of Nepalese Society of Periodontology and Oral Implantology Vol. 1, No. 1 ( 2017-06-01), p. 17-22
    Details
    In: Journal of Nepalese Society of Periodontology and Oral Implantology, Nepal Journals Online (JOL), Vol. 1, No. 1 ( 2017-06-01), p. 17-22
    Abstract: Background: Operator safety during dental & periodontal treatment is a non-negotiable necessity. The production of airborne material, during dental procedures is obvious to the dentist, dental team and the patient. Aim: The aim of the present study was to evaluate, the colony forming units (CFU) generated from aerosol during ultrasonic procedure in gingivitis and periodontitis subjects that act as a potential risk factor for spread of infectious agents for both operator and patients. Materials and Methods: The present study included 18 subjects which were randomly assigned into 3 equal groups. Group I (Control group) subjects were treated with ultrasonic scaling alone, whereas; Groups II & Group III (Test groups) subjects used pre-procedural mouth-rinses before scaling & root planing (Chlorhexidine and Povidone Iodine). Blood agar plates were used to assess the aerosol contamination and were placed at operator’s eye level, subject’s eye & chest level. These plates were then incubated for 72 hours and microbial growth were quantified as colony forming units (CFU/plate). Different colonies were identified by standard biochemical methods. Results: This study showed that the antiseptic mouth-rinses significantly reduce the bacterial CFU in the aerosol. Povidone Iodine was found to be superior to Chlorhexidine when used pre-procedurally. Conclusion: The following conclusion was drawn that the use of pre-procedural rinses significantly reduced the aerosol contamination and hence chances of cross-infection in the dental units.
    Type of Medium: Online Resource
    ISSN: 2565-4845 , 2542-2863
    URL: Article
    DOI: 10.3126/jnspoi.v1i1.23522
    Language: Unknown
    Publisher: Nepal Journals Online (JOL)
    Publication Date: 2017
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