Publication Date:
2014-12-18
Description:
Nature Chemistry 7, 82 (2015). doi:10.1038/nchem.2112 Authors: Christopher G. Newton, Samuel L. Drew, Andrew L. Lawrence, Anthony C. Willis, Michael N. Paddon-Row & Michael S. Sherburn The pseudopterosins are a family of natural products whose interesting anti-inflammatory and pain-relieving properties have inspired many synthetic approaches. Now, an unusual approach that starts with an axially chiral hydrocarbon that engages in a triple Diels–Alder sequence has been shown to result in the shortest total synthesis of a pseudopterosin so far.
Print ISSN:
1755-4330
Electronic ISSN:
1755-4349
Topics:
Chemistry and Pharmacology
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