Publication Date:
2015-03-03
Description:
Nature Reviews Rheumatology 11, 131 (2015). doi:10.1038/nrrheum.2014.210 Authors: Chrysothemis C. Brown & Lucy R. Wedderburn Can a patient's genotype provide insight into the mechanistic basis of autoimmune disease? A study integrating epigenetic data with finely mapped disease-associated variants sheds light on how noncoding variants might alter gene expression within specific immune cells, and hints at new possibilities for individualizing treatment of autoimmune rheumatic disorders.
Topics:
Medicine
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