Publication Date:
2013-03-21
Description:
The EMBO Journal 32, 844 (2013). doi:10.1038/emboj.2013.25 Authors: Zhonglei Lu, Genevieve Marcelin, Frederick Bauzon, Hongbo Wang, Hao Fu, Siok Le Dun, Hongling Zhao, Xiaosong Li, Young-Hwan Jo, Sharon Wardlaw, Nae Dun, Streamson Chua & Liang Zhu pRb is frequently inactivated in tumours by mutations or phosphorylation. Here, we investigated whether pRb plays a role in obesity. The Arcuate nucleus (ARC) in hypothalamus contains antagonizing POMC and AGRP/NPY neurons for negative and positive energy balance, respectively. Various aspects of ARC neurons are
Keywords:
E2F1high-fat dietobesityPOMC neuronspRb phosphorylation
Print ISSN:
0261-4189
Electronic ISSN:
1460-2075
Topics:
Biology
,
Medicine
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