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  • Articles  (14)
  • Nature Publishing Group (NPG)  (8)
  • Wiley-Blackwell  (6)
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  • Articles  (14)
  • 1
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Biopolymers 11 (1972), S. 197-214 
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Our previous paper described graphical procedures for evaluating the mode of association in ideal discrete and indefinite cases. This paper concerns the application of such procedures in cases where the non-ideality term BM1 must be considered. Bovine liver L-glutamate dehydrogenase and lysozyme are used as model systems. Several graphical procedures for dealing with cases of 1 - m, 1 - m - n, or indefinite association are developed. The procedure is based on the evaluation of the weight-fraction monomer with-out prior calculation of BM1, using graphical analysis to evaluate the non-ideality term.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 34 (1994), S. 174-189 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The present paper proposes “Deformation Characteristics” (DC) as a new deformation measure of screw extrusion processes, based on the Green deformation tensor. In contrast to previous strain measures heuristically proposed by Mohr, et al., Mckelvey, and Pinto and Tadmor, the new DC can naturally incorporate the demixing phenomena and systematically take into account the three-dimensional circulatory flow with the screw flight effect. Therefore, DC can be regarded as an improved strain measure. “Weighted Average Deformation characteristics” (WADC) is also proposed to indicate the overall deformation characteristics as a quantitative measure to the “goodness of mixing” of the extrusion process. The present paper includes discussion on delicate differences between DC and several other strain measures in case of the two-dimensional velocity approximation, and on the application of DC into a general three-dimensional velocity field obtained by a quasi-three-dimensional finite element analysis of extrusion processes. In determining WADC in the three-dimensional application, the residence time distribution function, including the three-dimensional circulatory flow effect, is used.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 35 (1995), S. 274-283 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: It is of great importance in designing extruders to predict the screw characteristics, that is, the throughput in terms of the screw speed and the pressure gradient along the down-channel direction. The screw characteristics depend on the extruder geometry, the operating conditions, and material properties of non-Newtonian fluids. This paper suggests a simple approach to determining the screw characteristics for a three-dimensional flow in a channel with a finite aspect ratio (ratio of a width to a depth, W/H) by introducing a Total Shape Factor (Ft) to correct a two-dimensional flow analysis for a channel with an infinite aspect ratio. In the present study, the Total Shape Factor (Ft) was defined as a ratio of a net flow rate obtained by the three-dimensional analysis to that by the two-dimensional analysis. In the proposed approach, the quantity, ∂Ft/∂(H/W), which turns out to be almost constant, offers important information for understanding the effects of the flights. Threfore, ∂Ft/∂(H/W) is extensively reported in this paper in terms of several dimensionless parameters. This simple approach with such a database will be very useful for extruder designers to predict screw characteristics.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Advances in Polymer Technology 15 (1996), S. 55-69 
    ISSN: 0730-6679
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In the accompanying article, Part I, we have described the basic mechanism of chaotic mixings due to a new “Chaos Screw” in single-screw extrusion processes, and presented experimental evidence of the chaotic mixing in a single-screw extruder with a typical Chaos Screw installed. The present article, Part II, will be focused on the numerical investigations of the chaotic flows via the Chaos Screw in a single-screw extruder. The three-dimensional velocity fields in both the no-barrier and barrier regions were separately calculated via a finite element analysis of the quasi-three-dimensional flow in each region, and were subsequently used in the numerical simulations of chaotic flow behaviors. Extensive numerical simulation results will be presented in terms of particle trajectories, Poincaré sections, and mixing patterns for several dimensionless parameters. It was found that invariant manifolds obtained by numerical simulations were in good agreement with those from experiments. © 1996 John Wiley & Sons, Inc.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Advances in Polymer Technology 15 (1996), S. 41-54 
    ISSN: 0730-6679
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: As far as the mixing performance in single-screw extrusion processes is concerned, it is well known that the deformation measure or stretching which materials undergo due to the regular flows inside a conventional screw channel increases linearly with the extruder channel length. In general, the chaotic mixing is far superior to the regular mixing. Therefore, it would be fascinating if one could make the chaotic mixing possible in single-screw extruders with a special, and yet easily manufacturable screw without sacrificing the pumping performance of single-screw extruders. With this purpose in mind, we have developed a new screw (termed “Chaos Screw”) for the single-screw extrusion process to enhance the mixing performance via the chaotic flows. The main idea of the Chaos Screw design lies in the spatially periodic barriers inserted in the channel to break closed streamlines in regular flows, which induces the chaotic mixing. The present article describes the basic mechanism of the chaotic mixing in a single-screw extruder and presents experimental evidence of the chaotic mixing using the Chaos Screw. Experimental mixing patterns due to the chaotic flow clearly indicate that the Chaos Screw drastically enhances the mixing performance in a single-screw extruder. It may be mentioned that the accompanying article, Part II, presents numerical investigation which shows that the chaotic mixing was successfully predicted by numerical simulations. © 1996 John Wiley & Sons, Inc.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Publication Date: 2015-10-17
    Description: Radiation promotes invasiveness of non-small-cell lung cancer cells through granulocyte-colony-stimulating factor Oncogene 34, 5372 (16 October 2015). doi:10.1038/onc.2014.466 Authors: Y-H Cui, Y Suh, H-J Lee, K-C Yoo, N Uddin, Y-J Jeong, J-S Lee, S-G Hwang, S-Y Nam, M-J Kim & S-J Lee
    Print ISSN: 0950-9232
    Topics: Medicine
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  • 7
    Publication Date: 2014-09-10
    Description: Most runoff analyses using a grid-based distributed model use one parameter group calibrated at the outlet of a watershed, instead of dividing the watershed into subwatersheds. Significant differences between the observed value and the simulation result of the subwatersheds can occur if just one parameter group is used in all subwatersheds that have different hydrological characteristics from each other. Therefore, to improve the simulation results of the subwatersheds within a watershed, a model calibrated at every subwatershed needs to be used to reflect the characteristics of each subwatershed. In this study, different parameter groups were set up for one or two sites using a distributed model, the GRM (Grid based Rainfall-runoff Model), and the evaluations were based on the results of rainfall-runoff analysis, which uses a multi-site calibration (MSC) technique to calibrate the model at the outlet of each site. The Hyangseok watershed in Naeseong River, which is a tributary of Nakdong River in Korea, was chosen as the study area. The watershed was divided into 5 subwatersheds each with a subwatershed outlet that was applied to the calibration sites. The MSC was applied for 5 cases. When a site was added for calibration in a watershed, the runoff simulation showed better results than the calibration of only one site at the most downstream area of the watershed. The MSC approach could improve the simulation results on the calibrated sites and even on the non-calibrated sites, and the effects of MSC improved when the calibrated site was closer to the runoff site. This article is protected by copyright. All rights reserved.
    Print ISSN: 0885-6087
    Electronic ISSN: 1099-1085
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Published by Wiley-Blackwell
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  • 8
    Publication Date: 2013-12-20
    Description: Cystatin SN neutralizes the inhibitory effect of cystatin C on cathepsin B activity Cell Death and Disease 4, e974 (December 2013). doi:10.1038/cddis.2013.485 Authors: J-T Kim, S-J Lee, M A Kang, J E Park, B-Y Kim, D-Y Yoon, Y Yang, C-H Lee, Y I Yeom, Y-K Choe & H G Lee
    Keywords: cystatin SNCystatin CCathepsin Bcolon cancerinvasion
    Electronic ISSN: 2041-4889
    Topics: Biology , Medicine
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  • 9
    Publication Date: 2014-02-11
    Description: Cyclophilin B is involved in p300-mediated degradation of CHOP in tumor cell adaptation to hypoxia Cell Death and Differentiation 21, 438 (March 2014). doi:10.1038/cdd.2013.164 Authors: K Jeong, H Kim, K Kim, S-J Kim, B-S Hahn, G-H Jahng, K-S Yoon, S S Kim, J Ha, I Kang & W Choe
    Keywords: CHOPCyclophilin Bendoplasmic reticulum stressp300ubiquitination
    Print ISSN: 1350-9047
    Electronic ISSN: 1476-5403
    Topics: Biology , Medicine
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  • 10
    Publication Date: 2017-06-09
    Description: Oncogenic BRAF fusions in mucosal melanomas activate the MAPK pathway and are sensitive to MEK/PI3K inhibition or MEK/CDK4/6 inhibition Oncogene 36, 3334 (8 June 2017). doi:10.1038/onc.2016.486 Authors: H S Kim, M Jung, H N Kang, H Kim, C-W Park, S-M Kim, S J Shin, S H Kim, S G Kim, E K Kim, M R Yun, Z Zheng, K Y Chung, J Greenbowe, S M Ali, T-M Kim & B C Cho
    Print ISSN: 0950-9232
    Topics: Medicine
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