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  • Nature Publishing Group (NPG)  (1)
  • Springer International Publishing  (1)
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  • 1
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    Springer International Publishing
    In:  In: Submarine Mass Movements and Their Consequences : 7th International Symposium. , ed. by Lamarche, G., Mountjoy, J., Bull, S. and Hubble, T. Advances in Natural and Technological Hazards Research, 37 . Springer International Publishing, Cham, pp. 419-426. ISBN 9783319209784
    Publication Date: 2021-05-11
    Description: Submarine spreading is a type of mass movement that involves the extension and fracturing of a thin surficial layer of sediment into coherent blocks and their finite displacement on a gently sloping slip surface. Its characteristic seafloor signature is a repetitive pattern of parallel ridges and troughs oriented perpendicular to the direction of mass movement. We map ~30 km2 of submarine spreads on the upper slope of the Hikurangi margin, east of Poverty Bay, North Island, New Zealand, using multibeam echosounder and 2D multichannel seismic data. These data show that spreading occurs in thin, gently-dipping, parallel-bedded clay, silt and sandy sedimentary units deposited as lowstand clinoforms. More importantly, high-amplitude and reverse polarity seismic reflectors, which we interpret as evidence of shallow gas accumulations, occur extensively in the fine sediments of the upper continental slope, but are either significantly weaker or entirely absent where the spreads are located. We use this evidence to propose that shallow gas, through the generation of pore pressure, has played a key role in establishing the failure surface above which submarine spreading occurred. Additional dynamic changes in pore pressure could have been triggered by a drop in sea level during the Last Glacial Maximum and seismic loading.
    Type: Book chapter , NonPeerReviewed
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  • 2
    Publication Date: 2013-05-01
    Description: IL-6 plays a central role in supporting pathological TH2 and TH17 cell development and inhibiting the protective T regulatory cells in allergic asthma. TH17 cells have been demonstrated to regulate allergic asthma in general and T-bet-deficiency-induced asthma in particular. Here we found an inverse correlation between T-bet and Il-6 mRNA expression in asthmatic children. Moreover, experimental subcutaneous immunotherapy (SIT) in T-bet(−/−) mice inhibited IL-6, IL-21R and lung TH17 cells in a setting of asthma. Finally, local delivery of an anti-IL-6R antibody in T-bet(−/−) mice resulted in the resolution of this allergic trait. Noteworthy, BATF, crucial for the immunoglobulin-class-switch and TH2,TH17 development, was found down-regulated in the lungs of T-bet(−/−) mice after SIT and after treatment with anti-IL-6R antibody, indicating a critical role of IL-6 in controlling BATF/IRF4 integrated functions in TH2, TH17 cells and B cells also in a T-bet independent fashion in allergic asthma. Scientific Reports 3 doi: 10.1038/srep01754
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
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