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  • 1
    Electronic Resource
    Electronic Resource
    A note on solitary waves along potential vorticity fronts on anf-plane (1993)
    Springer
    Journal of oceanography 49 (1993), S. 477-489 
    Details
    ISSN: 1573-868X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The effects of short waves on the propagration of velocity discontinuity along the interface of two uniform potential vorticity, zones on anf-plane is examined. It is shown, using a multiple scale analysis, that the dispersion introduced by the short waves can balance the nonlinear steepening effects predicted by the semigeostrophic theory. The time evolution of a shear disturbance along the front is governed by a Korteweg-de Vries equation. Numerical solutions of the solitary waves along the front are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02237456
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Evaluation of biodegradability by the reduction of Tetrazolium Violet in Biolog microplates (2000)
    Springer
    Biotechnology letters 22 (2000), S. 909-913 
    Details
    ISSN: 1573-6776
    Keywords: biodegradability ; biodegradation test ; Biolog microplates ; ozonation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract A novel biodegradation test using Biolog MT microplates was developed. The method was based on the reduction of Tetrazolium Violet during mineralization of organic substrates. Both a microbial mixed culture (activated sludge) and pure culture of a bacterium (Pseudomonas aeruginosa) were used as inocula to evaluate its applicability. The procedure was successfully demonstrated with the ozonated samples of p-nitrophenol. Compared with previous methods, the proposed method is fast and convenient to use in practice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1005608113423
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Effect of preganglionic sympathectomy on the cholinesterase activity in the superior cervical ganglia of rats and hamsters (1977)
    Springer
    Cell & tissue research 179 (1977), S. 111-120 
    Details
    ISSN: 1432-0878
    Keywords: Superior cervical ganglia ; Adrenergic neurons ; Cholinergic neurons ; Cholinesterase ; Acetylcholinesterase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary By employing biochemical assay and histochemical enzyme techniques the effect of preganglionic sympathectomy on the cholinesterase (ChE) activity in the superior cervical ganglia of rats and hamsters was investigated. Biochemical assays indicate that the ChE activity in the superior cervical ganglia of adult rats and hamsters is 57.19 and 28.63 respectively (expressed in u moles acetylcholine hydrolyzed per min per g of tissue); two weeks after preganglionic denervation, about 50% and 60% of ChE activity are lost respectively. Histochemical enzyme examination reveals that in the rat superior cervical ganglion, the majority of the neurons are adrenergic with weak to moderate acetylcholinesterase (AChE) reaction and the minority of the neurons are cholinergic with strong AChE activity, while only one type of adrenergic neurons exhibits a weak AChE activity in the hamster superior cervical ganglion. The AChE activity is localized in the perinuclear area, in the cisternae of the rough surfaced endoplasmic reticulum, in the Golgi complex and on the plasma membrane of the hamster's neurons; it is mainly localized in the cisternae of the rough surfaced endoplasmic reticulum of the rat's neurons. AChE reaction product is also detected on the axolemmal membranes of the preganglionic nerve fibers in the sympathetic ganglia of rats and hamsters. After preganglionic sympathectomy, the AChE activity in the adrenergic neurons and in the preganglionic unmyelinated nerve fibers is markedly reduced, whereas the cholinergic neurons and preganglionic myelinated nerve fibers remain unchanged. On the basis of these results two conclusions have been reached: (1) The fact that strong AChE activity localized in the cholinergic neurons and preganglionic myelinated fibers is not influenced by denervation, suggests that these structures are able to produce AChE. (2) The reduction of AChE activity in the rat and hamster superior cervical ganglia two weeks after preganglionic denervation, observed by histochemical examination, can be correlated with a concomitant measurable reduction determined by biochemical assays.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00278466
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    Paper (German National Licenses)
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  • 4
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    Western boundary currents regulated by interaction between ocean eddies and the atmosphere (2016)
    Nature Research
    In:  Nature, 535 (7613). pp. 533-537.
    Details
    Publication Date: 2019-09-23
    Description: Current climate models systematically underestimate the strength of oceanic fronts associated with strong western boundary currents, such as the Kuroshio and Gulf Stream Extensions, and have difficulty simulating their positions at the mid-latitude ocean’s western boundaries1. Even with an enhanced grid resolution to resolve ocean mesoscale eddies—energetic circulations with horizontal scales of about a hundred kilometres that strongly interact with the fronts and currents—the bias problem can still persist2; to improve climate models we need a better understanding of the dynamics governing these oceanic frontal regimes. Yet prevailing theories about the western boundary fronts are based on ocean internal dynamics without taking into consideration the intense air–sea feedbacks in these oceanic frontal regions. Here, by focusing on the Kuroshio Extension Jet east of Japan as the direct continuation of the Kuroshio, we show that feedback between ocean mesoscale eddies and the atmosphere (OME-A) is fundamental to the dynamics and control of these energetic currents. Suppressing OME-A feedback in eddy-resolving coupled climate model simulations results in a 20–40 per cent weakening in the Kuroshio Extension Jet. This is because OME-A feedback dominates eddy potential energy destruction, which dissipates more than 70 per cent of the eddy potential energy extracted from the Kuroshio Extension Jet. The absence of OME-A feedback inevitably leads to a reduction in eddy potential energy production in order to balance the energy budget, which results in a weakened mean current. The finding has important implications for improving climate models’ representation of major oceanic fronts, which are essential components in the simulation and prediction of extratropical storms and other extreme events3, 4, 5, 6, as well as in the projection of the effect on these events of climate change.
    Type: Article , PeerReviewed
    Format: text
    DOI: 10.1038/nature18640
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    OceanRep: Article in a Scientific Journal - peer-reviewed
  • 5
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    Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma (2015)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2015-08-28
    Description: Nature Genetics 47, 1061 (2015). doi:10.1038/ng.3358 Authors: Lu Jiang, Zhao-Hui Gu, Zi-Xun Yan, Xia Zhao, Yin-Yin Xie, Zi-Guan Zhang, Chun-Ming Pan, Yuan Hu, Chang-Ping Cai, Ying Dong, Jin-Yan Huang, Li Wang, Yang Shen, Guoyu Meng, Jian-Feng Zhou, Jian-Da Hu, Jin-Fen Wang, Yuan-Hua Liu, Lin-Hua Yang, Feng Zhang, Jian-Min Wang, Zhao Wang, Zhi-Gang Peng, Fang-Yuan Chen, Zi-Min Sun, Hao Ding, Ju-Mei Shi, Jian Hou, Jin-Song Yan, Jing-Yi Shi, Lan Xu, Yang Li, Jing Lu, Zhong Zheng, Wen Xue, Wei-Li Zhao, Zhu Chen & Sai-Juan Chen Natural killer/T-cell lymphoma (NKTCL) is a malignant proliferation of CD56+ and cytoCD3+ lymphocytes with aggressive clinical course, which is prevalent in Asian and South American populations. The molecular pathogenesis of NKTCL has largely remained elusive. We identified somatic gene mutations in 25 people with NKTCL by whole-exome sequencing and confirmed them in an extended validation group of 80 people by targeted sequencing. Recurrent mutations were most frequently located in the RNA helicase gene DDX3X (21/105 subjects, 20.0%), tumor suppressors (TP53 and MGA), JAK-STAT-pathway molecules (STAT3 and STAT5B) and epigenetic modifiers (MLL2, ARID1A, EP300 and ASXL3). As compared to wild-type protein, DDX3X mutants exhibited decreased RNA-unwinding activity, loss of suppressive effects on cell-cycle progression in NK cells and transcriptional activation of NF-κB and MAPK pathways. Clinically, patients with DDX3X mutations presented a poor prognosis. Our work thus contributes to the understanding of the disease mechanism of NKTCL.
    Print ISSN: 1061-4036
    Electronic ISSN: 1546-1718
    Topics: Biology , Medicine
    Published by Nature Publishing Group (NPG)
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  • 6
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    Integrated multi-omics analyses reveal the biochemical mechanisms and phylogenetic relevance of anaerobic androgen biodegradation in the environment (2016)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2016-07-27
    Description: Integrated multi-omics analyses reveal the biochemical mechanisms and phylogenetic relevance of anaerobic androgen biodegradation in the environment The ISME Journal 10, 1967 (August 2016). doi:10.1038/ismej.2015.255 Authors: Fu-Chun Yang, Yi-Lung Chen, Sen-Lin Tang, Chang-Ping Yu, Po-Hsiang Wang, Wael Ismail, Chia-Hsiang Wang, Jiun-Yan Ding, Cheng-Yu Yang, Chia-Ying Yang & Yin-Ru Chiang
    Print ISSN: 1751-7362
    Electronic ISSN: 1751-7370
    Topics: Biology
    Published by Nature Publishing Group (NPG) on behalf of The International Society for Microbial Ecology (ISME).
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    PAPER CURRENT
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