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  • 1
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A complete copy of the mRNA sequences encoding human coagulation factor VIII:C has been cloned and expressed. The DNA sequence predicts a single chain precursor of 2,351 amino acids with a relative molecular mass (Mr) 267,039. The protein has an obvious domain structure, contains ...
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  • 2
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The close association of Alu segments with a transfected oncogene provides one means of determining a structural outline of the transforming region. In Fig. 1, lanes a, b, we show the pattern of A /"-containing, EcoRl segments found in the DNAs of secondary foci induced by serial passage of the ...
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 327 (1987), S. 47-49 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The new instrument is a free-fall profiler very similar in design to the Total Ocean Profiler (TOPS) of S. Hayes of the Pacific Marine Environmental Laboratory9. Data from acoustic current meters, accelerometers and magnetometers are used in a model of the profiler's dynamic response to generate ...
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  • 4
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We synthesized a pool of ~1013 96-mer oligodeoxyribonucleotides that share 18-nucleotide binding sites for polymerase chain reaction (PCR) primers at their 5' and 3' termini and also contain 60-nucleotide randomly generated sequences. Using a 5'-biotinylated primer for one strand, ...
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  • 5
    Publication Date: 2023-11-08
    Description: Climate variability in the tropical Atlantic Ocean is determined by large-scale ocean–atmosphere interactions, which particularly affect deep atmospheric convection over the ocean and surrounding continents1. Apart from influences from the Pacific El Niño/Southern Oscillation2 and the North Atlantic Oscillation3, the tropical Atlantic variability is thought to be dominated by two distinct ocean–atmosphere coupled modes of variability that are characterized by meridional4, 5 and zonal6, 7 sea-surface-temperature gradients and are mainly active on decadal and interannual timescales, respectively8, 9. Here we report evidence that the intrinsic ocean dynamics of the deep equatorial Atlantic can also affect sea surface temperature, wind and rainfall in the tropical Atlantic region and constitutes a 4.5-yr climate cycle. Specifically, vertically alternating deep zonal jets of short vertical wavelength with a period of about 4.5 yr and amplitudes of more than 10 cm s−1 are observed, in the deep Atlantic, to propagate their energy upwards, towards the surface10, 11. They are linked, at the sea surface, to equatorial zonal current anomalies and eastern Atlantic temperature anomalies that have amplitudes of about 6 cm s−1 and 0.4 °C, respectively, and are associated with distinct wind and rainfall patterns. Although deep jets are also observed in the Pacific12 and Indian13 oceans, only the Atlantic deep jets seem to oscillate on interannual timescales. Our knowledge of the persistence and regularity of these jets is limited by the availability of high-quality data. Despite this caveat, the oscillatory behaviour can still be used to improve predictions of sea surface temperature in the tropical Atlantic. Deep-jet generation and upward energy transmission through the Equatorial Undercurrent warrant further theoretical study.
    Type: Article , PeerReviewed
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  • 6
    Publication Date: 2022-05-25
    Description: Author Posting. © Sears Foundation for Marine Research, 2005. This article is posted here by permission of Sears Foundation for Marine Research for personal use, not for redistribution. The definitive version was published in Journal of Marine Research 63 (2005): 263-289, doi:10.1357/0022240053693842.
    Description: A large tank capable of long-term maintenance of a sharp temperature-salinity interface has been developed and applied to measurements of the dynamical response of oceanographic sensors. A two-layer salt-stratified system is heated from below and cooled from above to provide two convectively mixed layers with a thin double-diffusive interface separating them. A temperature jump exceeding 10°C can be maintained over 1–2 cm (a vertical temperature gradient of order 103°C/m) for several weeks. A variable speed-lowering system allows testing of the dynamic response of conductivity and temperature sensors in full-size oceanographic instruments. An acoustic echo sounder and shadowgraph system provide nondisruptive monitoring of the interface and layer microstructure. Tests of several sensor systems show how data from the facility is used to determine sensor response times using several fitting techniques and the speed dependence of thermometer time constants is illustrated. The linearity of the conductivity–temperature relationship across the interface is proposed as a figure of merit for design of lag-correction filters to accurately match temperature and conductivity sensors for the computation of salinity. The effects of finite interface thickness, slow sensor sampling rates and the thermal mass of the conductivity cell are treated. Sensor response characterization is especially important for autonomous instruments where data processing and compression must be performed in-situ, but is also helpful in the development of new sensors and in assuring accurate salinity records from traditional wire-lowered and towed systems.
    Description: This research was supported by the National Science Foundation, grants OCE-97-11869 and OCE-02-40956, NOAA CORC grant 154368 and a WHOI Mellon Technical Staff Award.
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 7
    Publication Date: 2022-05-26
    Description: Author Posting. © Sears Foundation for Marine Research, 2008. This article is posted here by permission of Sears Foundation for Marine Research for personal use, not for redistribution. The definitive version was published in Journal of Marine Research 66 (2008): 413-440, doi:10.1357/002224008787157467.
    Description: The NATRE fine- and microstructure data set is revisited to test salt-finger amplitude theories. Dependences of the mixing efficiency Γ, microscale buoyancy Reynolds number Re and thermal Cox number CxT on 5-m density ratio Rρ and gradient Richardson number Ri are examined. The observed mixing efficiency is too high to be explained by linear fastest-growing fingers but can be reproduced by wavenumbers 0.5-0.9 times lower than the fastest-growing wavenumber. Constraining these fingers with a hybrid wave/finger Froude number or a finger Reynolds number cannot reproduce the observed trends with Rρ or Ri, respectively. This suggests that background shear has no influence on finger amplitudes. Constraining average amplitudes of these lower-wavenumber fingers with finger Richardson number Rif ~ 0.2 reproduces the observed dependence of Re and CxT on density ratio Rρ and Ri at all but the lowest observed density ratio (Rρ = 1.3). Separately relaxing the assumptions of viscous control, dominance of a single mode and tall narrow fingers does not explain the difference between theory and data at low Rρ for a critical Rif ~ 0.2.
    Description: We gratefully acknowledge the support of the Office of Naval Research (grant N00014-04-1-0212) and Natural Sciences and Engineering Research Council of Canada.
    Repository Name: Woods Hole Open Access Server
    Type: Article
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