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  • 1
    Online Resource
    Online Resource
    Pharmacotherapy of dementia
    National Library of Serbia ; 2010
    In:  Military Medical and Pharmaceutical Journal of Serbia Vol. 67, No. 5 ( 2010), p. 419-426
    Details
    In: Military Medical and Pharmaceutical Journal of Serbia, National Library of Serbia, Vol. 67, No. 5 ( 2010), p. 419-426
    Abstract: nema
    Type of Medium: Online Resource
    ISSN: 0042-8450 , 2406-0720
    URL: Article
    DOI: 10.2298/VSP1005419P
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2010
    detail.hit.zdb_id: 2169819-3
    SSG: 15,3
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  • 2
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    Online Resource
    Cognitive ability and motor performances in the elderly
    National Library of Serbia ; 2022
    In:  Military Medical and Pharmaceutical Journal of Serbia Vol. 79, No. 5 ( 2022), p. 465-474
    Details
    In: Military Medical and Pharmaceutical Journal of Serbia, National Library of Serbia, Vol. 79, No. 5 ( 2022), p. 465-474
    Abstract: Background/Aim. Aging entails a wide range of cognitive processes that are not independent of one another. It leads to changes in physical-motor characteristics and sometimes to disability. The aim of this study was to examine the association between multiple cognitive performances in elderly subjects and their physical-motor abilities. Method. The study included 98 elderly participants (60+) (16 males and 82 females). Cognitive abilities were assessed by the Montreal Cognitive Assessment (MoCA)/Serbian version, and physical measures were assessed by the Senior Fitness Test with its five subtests, supplemented by the Walking Speed Test. Results. Several MoCA items demonstrated relatively low variability, i.e., they proved to be too easy for most of the participants. The participants exhibited the lowest performance on the memory relating to other domains, followed by executive functions, visuospatial skills, attention, concentration, and working memory domains, with the highest performance on temporal and spatial orientation relating to other domains. Executive functions and language correlated most significantly with physical strength. Agility and dynamic balance, lower- and upper-body strength, and aerobic endurance correlated moderately and positively. Conclusion. This study underlines the positive correlation between physical fitness and cognitive level in the elderly and emphasizes the importance of physical fitness for cognitive functions, especially those of executive type in elderly subjects. Clinicians should consider the association between cognitive function and physical-motor performances when dealing with functioning improvement in the elderly. The importance of designing the most efficient exercise pro-grams to achieve maximal somatic and cognitive effects is emphasized.
    Type of Medium: Online Resource
    ISSN: 0042-8450 , 2406-0720
    URL: Article
    DOI: 10.2298/VSP200812143J
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2022
    detail.hit.zdb_id: 2169819-3
    SSG: 15,3
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  • 3
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    Online Resource
    The anterior cingulate cortex
    National Library of Serbia ; 2009
    In:  Arhiv za bioloske nauke Vol. 61, No. 4 ( 2009), p. 659-673
    Details
    In: Arhiv za bioloske nauke, National Library of Serbia, Vol. 61, No. 4 ( 2009), p. 659-673
    Abstract: Prednja cingularna kora ima ulogu u paznji, analizi senzornih informacija, prepoznavanjugreske, resavanju problema, otkrivanju onog sto je novo za jedinku, ponasanju, emocijama, socijalnim relacijama i kognitivnoj kontroli kao i regulaciji autonomnih funkcija. Ova area je aktivna kad god osoba dozivljava neka osecanja ili kada resava neke probleme i vrsi analizu za i protiv neke akcije odnosno da li je odluka ispravna. Analogne oblasti su nadjene i kod visih sisara, narocito kitova i kod svih postoje vretenasti neuroni koje omogucavaju slozene socijalne interakcije. Poremecaj funkcije prednje cingularne kore se vidja u demencijama, shizofreniji, depresiji, opsesivno-kompulsivnim poremecajima i drugim neuropsihijatrijskim bolestima.
    Type of Medium: Online Resource
    ISSN: 0354-4664 , 1821-4339
    URL: Article
    DOI: 10.2298/ABS0904659P
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2009
    detail.hit.zdb_id: 2380842-1
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  • 4
    Online Resource
    Online Resource
    The neuropsychology of hallucinations
    National Library of Serbia ; 2011
    In:  Arhiv za bioloske nauke Vol. 63, No. 1 ( 2011), p. 43-48
    Details
    In: Arhiv za bioloske nauke, National Library of Serbia, Vol. 63, No. 1 ( 2011), p. 43-48
    Abstract: nema
    Type of Medium: Online Resource
    ISSN: 0354-4664 , 1821-4339
    URL: Article
    DOI: 10.2298/ABS1101043P
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2011
    detail.hit.zdb_id: 2380842-1
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  • 5
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    Online Resource
    Hashimoto encephalopathy: Neurological and psychiatric perspective
    National Library of Serbia ; 2009
    In:  Arhiv za bioloske nauke Vol. 61, No. 3 ( 2009), p. 383-394
    Details
    In: Arhiv za bioloske nauke, National Library of Serbia, Vol. 61, No. 3 ( 2009), p. 383-394
    Abstract: Hasimoto encefalopatija (HE) je autoimuna bolest sa neuroloskim i neuropsihijatrijskim ispoljavanjima i povisenim titrovima antitireoidnih antitela u serumu i cerebrospinalnoj tecnosti. Bolesnici su uglavnom zene. Uzrast varira od 8 do 86 godina. Prevalenca HE se procenjuje na 2,1/100000. Neuroloski i/ili psihijatrijski simptomi i znaci sacinjavaju klinicku sliku. Bolest reaguje dobro na kortikosteroidnu terapiju, ali nekad se mora primeniti i druga imunomodulatorn a terapija. Pretpostavlja se autoimuni mehanizam sa antitelima na antigene mozdane kore. Tok bolesti moze biti akutan, subakutan, hronican i remitentan. Neki bolesnici se oporave spontano, ali ima i letalnih ishoda uprkos adekvatnoj terapiji.
    Type of Medium: Online Resource
    ISSN: 0354-4664 , 1821-4339
    URL: Article
    DOI: 10.2298/ABS0903383P
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2009
    detail.hit.zdb_id: 2380842-1
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  • 6
    Online Resource
    Online Resource
    Antiphospholipid syndrome
    National Library of Serbia ; 2010
    In:  Srpski arhiv za celokupno lekarstvo Vol. 138, No. 9-10 ( 2010), p. 651-657
    Details
    In: Srpski arhiv za celokupno lekarstvo, National Library of Serbia, Vol. 138, No. 9-10 ( 2010), p. 651-657
    Abstract: Antifosfolipidni sindrom (AFS) je autoimuna bolest s ponavljanim trombozama i komplikacijama trudnoce, a 90% bolesnika su zene. AFS moze da bude primaran i sekundaran kada je udruzen s nekom autoimunom bolescu. Antifosfolipidna antitela deluju protromboticki, ali i direktno na mozdano tkivo. Za postavljanje dijagnoze neophodno je da se ispune jedan klinicki i jedan laboratorijski kriterijum. Pozitivan seroloski test mora se potvrditi posle najmanje 12 nedelja. Javljaju se tromboze u mnogim organima i spontani pobacaji, nekad trombocitopenija i hemoliticka anemija, a neuroloski poremecaji, tegobe i stanja su najcesci, i to: glavobolje, mozdani udar, encefalopatija, epilepsija, smetnje vida, Snedonov (Sneddon) sindrom, demencija, vrtoglavica, horea, balizam, prolazna opsta amnezija, psihoza, transverzalna mijelopatija i Giljen-Bareov (Guillain-Barrj) sindrom. Oko 50% mozdanih udara kod osoba mladjih od 50 godina nastaje usled AFS. Prva linija terapije kod mozdanog udara je antikoagulantna terapija: intravenski heparin ili niskomolekularni heparini. U lecenju hronicnog AFS primenjuju se oralna antikoagulantna i antiagregaciona terapija, varfarin i acetilsalicilna kiselina, najcesce dozivotno. Kod bolesnika rezistentnih na lecenje primenjuju se kortikosteroidi, intravenski imunoglobulini i terapijska izmena plazme. Prognoza kod vecine bolesnika je dobra, a kod onih koji ne reaguju dobro na lecenje nastaju ponavljane tromboze, pa i smrt.
    Type of Medium: Online Resource
    ISSN: 0370-8179 , 2406-0895
    URL: Article
    DOI: 10.2298/SARH1010651P
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2010
    detail.hit.zdb_id: 2577665-4
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  • 7
    Online Resource
    Online Resource
    Vitamin B1, eye and brain
    National Library of Serbia ; 2022
    In:  Srpski arhiv za celokupno lekarstvo Vol. 150, No. 3-4 ( 2022), p. 233-237
    Details
    In: Srpski arhiv za celokupno lekarstvo, National Library of Serbia, Vol. 150, No. 3-4 ( 2022), p. 233-237
    Abstract: Vitamin B1 (aneurin, thiamine) is a water-soluble vitamin necessary for the normal function of the nervous system, visual system and heart and is part of important enzymes in the body. Thiamine enables the normal use of glucose, other carbohydrates and proteins, and enables the supply of energy to the organism. The main sources of thiamine are exogenous and small amounts are synthesized by microorganisms of the human intestinal microbiome. Vitamin B1 cannot accumulate in the body, so signs of deficiency are quickly manifested. Hypovitaminosis B1 is seen in chronic ethyl abuse, persistent vomiting (as in some pregnant women) or after bariatric surgical procedures, but in a mild form it is present in the general population. Normal daily needs for vitamin B1 depend on calorie intake, and 0.4 mg should be ingested for every 1000 kcal.
    Type of Medium: Online Resource
    ISSN: 0370-8179 , 2406-0895
    URL: Article
    DOI: 10.2298/SARH210929019B
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2022
    detail.hit.zdb_id: 2577665-4
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  • 8
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    Online Resource
    Constructional apraxia in patients with closed head injury
    National Library of Serbia ; 2005
    In:  Military Medical and Pharmaceutical Journal of Serbia Vol. 62, No. 5 ( 2005), p. 339-342
    Details
    In: Military Medical and Pharmaceutical Journal of Serbia, National Library of Serbia, Vol. 62, No. 5 ( 2005), p. 339-342
    Abstract: Uvod. Konstrukcijska apraksija predstavlja poremecaj sposobnosti slaganja elemenata u celinu. Ovaj deficit je malo ispitivan kod bolesnika sa zatvorenom povredom glave (ZPG). Metode. Ispitan je 41 bolesnik sa ZPG, 11 (26,83%) sa desnostranom, 12 (29,27%) sa levostranom i 18 (43,90%) sa bilateralnom lezijom. Primenjeni su: Vekslerov individualni test inteligencije (VITI - srpska verzija), Rey Complex Figure (RCF) test, Trail Making Test - TMT A i B i Wisconsin Card Sorting Test (WCST). Rezultati. Koeficijent inteligencije (IQ) je bio znacajno visi kod bolesnika sa desnostranim (95,27) i bilateralnim mozdanim lezijama (87,56) nego kod onih sa levostranim (84,42). Ucinak na RCF se nije statisticki znacajno razlikovao u odnosu na stranu lezije, ali je numericki bio najnizi kod bolesnika sa bilateralnim ostecenjima. Bolesnici sa levostranim lezijama imali su skor 30,63, sa desnostranim 28,68, a sa bilateralnim lezijama 27,39. TMT B je pokazao znacajno nizi ucinak kod bolesnika sa levostranim (196,50 sekundi) i bilateralnim (192,07 sekundi) u odnosu na desnostrane lezije (140,14 sekundi). WCST nije pokazao znacajnu razliku u odnosu na stranu lezije, ali je apsolutni broj kategorija bio manji od ocekivanog. Zakljucak. Konstrukcijska apraksija je prisutnija kod bolesnika sa ZPG nego sto se to do sada mislilo. Primena osetljivih testova pokazuje da se poremecaj javlja prvenstveno kod bilateralnih, ali i kod unilateralnih lezija.
    Type of Medium: Online Resource
    ISSN: 0042-8450 , 2406-0720
    URL: Article
    DOI: 10.2298/VSP0505339P
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2005
    detail.hit.zdb_id: 2169819-3
    SSG: 15,3
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  • 9
    Online Resource
    Online Resource
    Pathogenesis of Alzheimer disease
    National Library of Serbia ; 2007
    In:  Military Medical and Pharmaceutical Journal of Serbia Vol. 64, No. 11 ( 2007), p. 765-772
    Details
    In: Military Medical and Pharmaceutical Journal of Serbia, National Library of Serbia, Vol. 64, No. 11 ( 2007), p. 765-772
    Abstract: 〈zakljucak〉 Alchajmerova bolest javlja se kod 50-60% svih dementnih osoba i predstavlja znacajan zdravstveni i socijalni problem. Upoznavanje patogeneze AB je neophodno u nalazenju terapija koje bi ublazile i modifikovale bolest. Najvise dokaza ima za hipotezu o amiloidnoj kaskadi. Osnovna patohistoloska promena u mozgu obolelih su nakupine amiloida beta (A beta), senilni ili amiloidni pakovi. Ukupni efekat je gubitak sinapsi i neurona. Amiloid se nakuplja i u zidovima krvnih sudova remeteci mozdanu cirkulaciju. Usled navedenih promena nastaje poremecaj neurotransmisije, narocito acetilholina i glutamata i smetnje pamcenja i drugih neuroloskih funkcija. Patogenetski zasnovana terapija se usmerava na aktivaciju alfa sekretaze, inhibiciji beta i gama sekretaza, pojacano uklanjanje A beta, suzbijanje oksidativnog stresa i inflamacije, imunoterapiju upravljenu protiv Abeta i druge mehanizme. U upotrebi su inhibitori ACh-esteraze i antagonista glutamatnih receptora. U prevenciji su dokazani efekti ogranicenog unosa kalorija, Mediteranske dijete i redovne umerene fizicke aktivnosti.
    Type of Medium: Online Resource
    ISSN: 0042-8450 , 2406-0720
    URL: Article
    DOI: 10.2298/VSP0711765P
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2007
    detail.hit.zdb_id: 2169819-3
    SSG: 15,3
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  • 10
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    Online Resource
    Neuropsychological assessment and treatment possibilities of cognitive deficit in schizophrenic patients
    National Library of Serbia ; 2012
    In:  Military Medical and Pharmaceutical Journal of Serbia Vol. 69, No. 6 ( 2012), p. 510-516
    Details
    In: Military Medical and Pharmaceutical Journal of Serbia, National Library of Serbia, Vol. 69, No. 6 ( 2012), p. 510-516
    Abstract: nema
    Type of Medium: Online Resource
    ISSN: 0042-8450 , 2406-0720
    URL: Article
    DOI: 10.2298/VSP1206510T
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2012
    detail.hit.zdb_id: 2169819-3
    SSG: 15,3
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