ISSN:
1600-0501
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Abstract: The aim of the present study was to analyze the levels of osteocalcin, deoxypyridinoline (Dpd) and interleukin-1β as markers of bone metabolism in peri-implant crevicular fluid (PICF) from peri-implantitis patients. PICF was sampled from a total of 34 endosseous titanium implants from 16 patients; nine females (mean age 52.8, range 40–62 years) and seven males (mean age 56.0, range 36–66 years). The implants had been in place for a period of 9–112 months (mean; 35.8 months) since the loading. These sites were categorized as six peri-implantitis, eight peri-implant mucositis and 20 healthy implant. PICF volume from peri-implantitis sites was significantly higher than mucositis and healthy implant sites (P 〈 0.01). Osteocalcin levels in PICF from mucositis sites were significantly higher than healthy implants (P 〈 0.05), whereas peri-implantitis sites were not significantly different from either mucositis or healthy implant sites. Dpd could not be detected in any of the samples examined. IL-1β levels in PICF from peri-implantitis sites were significantly higher than levels from peri-implant mucositis (P 〈 0.05) and healthy implant sites (P 〈 0.01). In conclusion, osteocalcin in PICF may reflect increased local bone turnover around implants. Further, IL-1β should be a useful marker for peri-implant inflammation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1034/j.1600-0501.2002.130610.x
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