In:
Urological Science, Medknow, Vol. 29, No. 6 ( 2018), p. 303-306
Abstract:
We aimed to analyze the renal stone composition and evaluate the epidemiology of body mass index (BMI) and renal stones. Materials and Methods: We conducted a retrospective, single-center study of patients with large stones ([Latin Small Letter LEZH] cm) who underwent percutaneous nephrolithotomy for renal stones between 2010 and 2015. We performed stone analysis using stereomicroscopy and infrared spectroscopy to determine the chemical composition of these stones. Chi-square analysis was used to determine the relationship between BMI and renal stone formation. Results: We examined stones from 191 procedures. Among these stones, we classified 58.6% as having “pure” composition and 40.8% as having “mixed” composition. Most stones (68.1%) were composed of calcium oxalate monohydrate (COM), followed by carbonate apatite (50.8%), calcium oxalate dihydrate (COD) (36.6%), uric acid (14.1%), struvite (8.9%), ammonium hydrogen urate (2.1%), and brushite (1.0%). Chi-square analysis revealed that stones in obese patients (BMI 〉 27 kg/m 2 ) were more likely to contain COM (hazards ratio [HR]: 1.66, 95% confidence interval [CI] : 1.10–2.49, P = 0.008) and less COD (HR: 0.77, 95% CI: 0.60–0.99, P = 0.049) than stones in nonobese patients (BMI ≦27 kg/m 2 ). Conclusion: COM is the most frequently occurring compound in renal stones. Obese patients were significantly more likely to develop COM-containing renal stones. One must consider these factors when choosing a treatment modality.
Type of Medium:
Online Resource
ISSN:
1879-5226
DOI:
10.4103/UROS.UROS_16_18
Language:
English
Publisher:
Medknow
Publication Date:
2018
detail.hit.zdb_id:
2556801-2
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