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  • 1
    Online Resource
    Online Resource
    Medip Academy ; 2019
    In:  International Journal of Research in Medical Sciences Vol. 7, No. 11 ( 2019-10-24), p. 4049-
    In: International Journal of Research in Medical Sciences, Medip Academy, Vol. 7, No. 11 ( 2019-10-24), p. 4049-
    Abstract: Background: Appendicitis is among most common cause for acute abdominal pain requiring operative management. This study is to establish relationship between wall thickness of acute appendicitis and recurrent appendicitis with its pathological outcome.Methods: In this prospective study, 24 patients of acute appendicitis and 8 patients of recurrent appendicitis presenting as acute appendicitis were examined by High resolution Ultrasonography within 48 hrs of acute onset of symptoms following a detailed clinical examination. Alvarado scoring was done in all patients. Acute appendicitis and recurrent appendicitis were differentiated on the basis of clinical details and timeline of illness. Post operatively all specimens underwent gross and histopath examination and were divided into subgroups and tabulated as “early acute appendicitis”, “acute suppurative appendicitis” and “acute gangrenous Appendicitis”.Results: Wall thickness of acute appendicitis and recurrent appendicitis (presenting with acute onset of symptoms) were tabulated. Patients with wall thickness of 〈 3mm had statistically significant higher prevalence of acute gangrenous appendicitis on pathological correlation. Patients with recurrent appendicitis had higher incidence of wall thickness 〈 3mm, consequently increased incidence of acute gangrenous appendicitis. The value of z was 6.0715. The value of p is 〈 0.00001. The result was significant at p 〈 0.01 according to SPSS 16, which correlates well with findings.Conclusions: Wall thickness is an important indicator in the management of acute or recurrent appendicitis, wall thickness of 〈 3mm or 〉 3mm was decisive in patient management. Reduced wall thickness of appendix in patients with acute or recurrent appendicitis correlate with higher incidence of acute gangrenous appendicitis therefore are at higher risk of perforation and should be managed aggressively by surgical intervention to avoid complications.
    Type of Medium: Online Resource
    ISSN: 2320-6012 , 2320-6071
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2019
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  • 2
    Online Resource
    Online Resource
    Medip Academy ; 2023
    In:  International Journal of Basic & Clinical Pharmacology Vol. 12, No. 5 ( 2023-08-25), p. 682-687
    In: International Journal of Basic & Clinical Pharmacology, Medip Academy, Vol. 12, No. 5 ( 2023-08-25), p. 682-687
    Abstract: Background: The increasing prevalence of hypertension is attributed to population growth, ageing and behavioural risk factors, such as unhealthy diet, harmful use of alcohol, lack of physical activity, excess weight and exposure to persistent stress. The aim of study is the prescribing pattern and the consumption of antihypertensive drugs in isolated hypertensive patients and in hypertensive patients with different co-existing morbidities. Methods: The present study is a Prospective observational study. The study was conducted at Medicine Department of associated hospital of RUHS College of Medical Sciences, Jaipur. Results: A total of 965 patients having hypertension were analyzed, in that 556 patients were male and 409 patients were female. In hypertension patients, angiotensin receptor blockers ARB, diuretics and β- blockers (29.90%) were mostly used classes in three drug therapy. Whereas telmisartan, hydrochlorothiazide and metoprolol (35.05%) were mostly prescribed. Drugs. In hypertension patients, angiotensin receptor blockers ARB, diuretics, β- blockers and calcium channel blockers (56.67%) and calcium channel blockers, angiotensin converting enzyme inhibitors, β-blockers and diuretics (43.33%) were used classes in four drug therapy. Whereas Telmisartan, Hydrochlorothiazide, Nebivolol and Amlodipine (62.5%) were mostly prescribed drugs. Hypertensive Patients with Comorbidity were found in higher prevalence with 276 hypertensive patients (28.60%) along with Diabetes Mellitus most commonly found and 389 hypertensive patients (40.31%) were found to be with No Comorbidity. Conclusions: Present results reveal that antihypertensive medication adherence to JNC-8 recommendations is suboptimal. Therefore, physicians should follow JNC-8 guidelines to improve the patients care because suboptimal adherence leads to adverse clinical outcomes. The present study demonstrated that physicians are not completely adhering to standard guidelines while treating hypertension with co-morbid conditions.
    Type of Medium: Online Resource
    ISSN: 2279-0780 , 2319-2003
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2023
    detail.hit.zdb_id: 2681376-2
    SSG: 15,3
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  • 3
    Online Resource
    Online Resource
    Medip Academy ; 2020
    In:  International Journal of Basic & Clinical Pharmacology Vol. 9, No. 6 ( 2020-05-21), p. 887-
    In: International Journal of Basic & Clinical Pharmacology, Medip Academy, Vol. 9, No. 6 ( 2020-05-21), p. 887-
    Abstract: Background: Antibiotics are most frequently prescribed and problem associated with antibiotics over and under use leads to treatment failure and on the other side resistance to drugs increases. Assessment of antibiotics prescribed is important for checking quality and standard of prescriptions. The objective of the study was done for assessing the prescribing pattern of antibiotics using WHO indicator in medicine ward of tertiary care teaching hospital.Methods: Prospective observational study was carried out for a period of six months in medicine ward after ethical committee approval. Data was collected in data collection forms and evaluated using WHO indicator.Results: A total of 190 prescriptions was collected in which 1145 drugs were prescribed. Total number of antibiotics in prescription was found to be 164. Percentage of antibiotics was found to be 14.32% which was according to WHO prescribing indicator. Various class of antibiotics was prescribed in which cephalosporin with total of 90 (54.87%) followed by penicillin 18 (10.97), macrolide 18 (10.97%) fluoroquinolones 11 (6.70%), nitroimidazole 8 (4.87%), amino glycoside 8 (4.87%) and other classes 11 (6.70%).Conclusions: The study shows that pattern of antibiotics was according to the WHO prescribing indicator but still practice was lacking in terms of selection of antibiotics as there was no culture sensitivity test was performed.
    Type of Medium: Online Resource
    ISSN: 2279-0780 , 2319-2003
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2020
    detail.hit.zdb_id: 2681376-2
    SSG: 15,3
    Location Call Number Limitation Availability
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  • 4
    In: International Journal of Basic & Clinical Pharmacology, Medip Academy, Vol. 12, No. 2 ( 2023-02-22), p. 222-226
    Abstract: Background: The Coronavirus disease 2019 (COVID-19) exploded into a global pandemic, killing over 6.5 million people and forever changing the world. While many developed countries are well into their vaccination campaigns, India outperformed global expectations by providing over 2 billion doses to its citizens and assisting other countries worldwide. Following the emergence of various covid variants, it is critical to comprehend the willingness of Indians to receive additional doses of the newer generation of covid vaccination, as well as the fatigue associated with maintaining the most essential covid appropriate behaviour, masking. This study aimed to determine general public attitudes and perceptions of the COVID-19 vaccine in India. Method: A pan-India cross-sectional analysis was conducted at RUHS college of medical sciences, Jaipur, between October 20, 2022, and December 15, 2022. Through web-based links, a self-administered and semi-structured questionnaire was used to collect data. Results: Of the total responses received (n=391), 55.6% were males, and 43.8% were females. 63.2% have received two doses of the vaccine, while 33.8% have received three doses. 50.9% of respondents were willing to take the fourth dose of the vaccine, 20.5% were utterly unwilling, and 28.6% were undecided. 10.7% of our respondents were utterly reluctant to wear masks, whereas 26.6% always did. Conclusions: Based on the findings, vaccination acceptance in India remains high with 50.9% of applicants willing to take the fourth dose. Furthermore, the pandemic has resulted in the incorporation of face masks into our lifestyles, with the majority of people using a face mask in at least one setting.
    Type of Medium: Online Resource
    ISSN: 2279-0780 , 2319-2003
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2023
    detail.hit.zdb_id: 2681376-2
    SSG: 15,3
    Location Call Number Limitation Availability
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  • 5
    In: International Journal of Basic & Clinical Pharmacology, Medip Academy, Vol. 12, No. 3 ( 2023-04-27), p. 402-405
    Abstract: Background: Skin diseases are chronic in nature and they require lifetime treatment. Prescription pattern reflects health professional attitude towards the disease and role of drugs in its treatment. The study of prescription pattern is important to make medical care rational and monitoring adverse drug reactions. Methods: An observational and prospective study was carried out in Skin and VD department along with department of pharmacology, RUHS college of medical sciences, Jaipur. Data collection was done in three months after ethical approval. Data was entered and analysed with latest Microsoft Excel version. Descriptive statistics were used to analyse the results. Results: During the study period, a total of 979 prescriptions were included and analysed, out of which the usage of dermatological drugs was maximum among males (n=520, 53.11%). Total 2848 drugs were prescribed in 6 different dosage forms. The most common dosage form prescribed was tablet (1267, 44.49%) followed by cream (685, 24.05%). Total 1632 (57.30%) drugs were prescribed through oral route and 1216 (42.70%) drugs were prescribed through topical route. the present study depicted that dermatophytosis (n=243, 24.82%) was one of the most common dermatological manifestations. antihistaminic (673, 23.63%) were the most commonly prescribed drug. Conclusions: The study of drug use is an effective tool to promote rational drug prescribing. Such type of study will help in formulation of proper antibiotics, drugs policy, prescription of cost-effective drugs, improvement in the patient compliance and reduction in undesirable effect of drugs.
    Type of Medium: Online Resource
    ISSN: 2279-0780 , 2319-2003
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2023
    detail.hit.zdb_id: 2681376-2
    SSG: 15,3
    Location Call Number Limitation Availability
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  • 6
    Online Resource
    Online Resource
    Medip Academy ; 2023
    In:  International Journal of Contemporary Pediatrics Vol. 10, No. 4 ( 2023-03-27), p. 579-581
    In: International Journal of Contemporary Pediatrics, Medip Academy, Vol. 10, No. 4 ( 2023-03-27), p. 579-581
    Abstract: The objective is to describe an uncommon case of Hirschsprung's disease (HD), also called congenital megacolon. The lack of neuronal ganglion cells from the submucosal and muscular nerve plexuses throughout a segment of varied length characterizes HD. Approx 94% of HD cases are diagnosed below the age of 5 years. A 3 years old male patient was admitted to the male surgery ward under a pediatric surgeon with the chief complaints of chronic constipation since birth with a history of delayed passage of meconium. The patient was diagnosed with a case of HD at the age of 1 year for which he was operated on colostomy was performed with multiple biopsies from narrowed rectosigmoid, from the transitional zone, and from colostomy stoma which confirmed the decision to make colostomy at the ganglionated segment of the colon based on the clinical picture during surgery. Biopsy report of narrowed rectosigmoid segment showed the absence of ganglion cells, while colostomy stoma and dilated proximal colon showed the presence of ganglion cells. The patient underwent a surgical procedure named pull-through surgery for HD, a martin's modification of the Duhamel operation.
    Type of Medium: Online Resource
    ISSN: 2349-3291 , 2349-3283
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2023
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