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  • Medip Academy  (3)
  • 1
    Online Resource
    Online Resource
    Medip Academy ; 2020
    In:  International Journal of Research in Dermatology Vol. 6, No. 4 ( 2020-06-23), p. 597-
    In: International Journal of Research in Dermatology, Medip Academy, Vol. 6, No. 4 ( 2020-06-23), p. 597-
    Abstract: 〈 p class="abstract" 〉 Coronaviruses are RNA viruses that have become a major public health concern since the severe acute respiratory syndrome CoV (SARS-CoV-2) outbreak in 2002. The continuous evolution of coronaviruses was further highlighted with the emergence of the middle east respiratory syndrome CoV (MERS-CoV) outbreak in 2012. The spike glycoprotein of SARS-CoV-2 plays a pivotal role in the entry of virus into the cell and it further interacts with ACE-II receptors which are widely distributed on the human cell surface especially on alveolar type II cells (AT-2) and endothelium. Currently, the world is concerned about the 2019 novel CoV (SARS-CoV-2) that was initially identified in the city of Wuhan, China in December 2019. Patients presented with severe viral pneumonia and respiratory illness. Despite the virus not being dermatotropic, several skin conditions have emerged mainly as a result of prolonged contact with personal protective equipment and excessive personal hygiene. In this review, we discuss structure, genome organisation, entry of CoVs into target cells, probable cutaneous manifestation that dermatologists may be aware of skin complications and the preventive measures, outcome of the disease and the management. 〈 /p 〉
    Type of Medium: Online Resource
    ISSN: 2455-4529
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2020
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  • 2
    Online Resource
    Online Resource
    Medip Academy ; 2021
    In:  International Journal of Research in Orthopaedics Vol. 7, No. 6 ( 2021-10-26), p. 1156-
    In: International Journal of Research in Orthopaedics, Medip Academy, Vol. 7, No. 6 ( 2021-10-26), p. 1156-
    Abstract: 〈 p class="abstract" 〉 〈 strong 〉 Background: 〈 /strong 〉 Inter-condylar fractures of the distal humerus are uncommon injuries and present the most difficult challenge among fractures of the lower end of the humerus. The principle involves anatomical reduction and fixation with stabilization of extra-osseous implants. The functional outcome has been greatly influenced by the early graduated rehabilitative exercise. We aimed to evaluate the functional outcome of inter-condylar fractures of the distal humerus in adults using bi-columnar plating through a trans-olecranon approach. 〈 /p 〉 〈 p class="abstract" 〉 〈 strong 〉 Methods: 〈 /strong 〉 A prospective study with 40 adult patients with inter-condylar fracture of the distal humerus were managed with bi-columnar plating through a trans-olecranon approach and were followed up for 12 months. The functional outcome was analysed by Mayo’s Elbow Performance Score (MEPS) at the end of 12 months follow up. 〈 /p 〉 〈 p class="abstract" 〉 〈 strong 〉 Results: 〈 /strong 〉 The average age of study participants were 50.8 years. A total of 24 cases were due to RTA and 16 cases were due to direct falls. Out of 40 cases, 6 (15%) were of B1 type, 2 (5%) were of type B2, 12 (30%) were of C1, 10 (25%) of C2, and 10 (25%) were of the type of C3 according to AO classification. According to MEPS at the end of the 12th-month follow-up, excellent results were seen in 24 (60%), good in 8 (20%), fair in 6 (15%), and poor results in 2 (5%) cases. 〈 /p 〉 〈 p class="abstract" 〉 〈 strong 〉 Conclusions: 〈 /strong 〉 Anatomically, bi-columnar plating for distal humerus is useful in providing stable fixation for complex distal articular fractured by trans-olecranon approach and facilitating early postoperative rehabilitation. Clinical and radiological results showed a good healing rate with a good range of motion.   〈 /p 〉
    Type of Medium: Online Resource
    ISSN: 2455-4510
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2021
    Location Call Number Limitation Availability
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  • 3
    In: International Journal of Research in Orthopaedics, Medip Academy, Vol. 4, No. 6 ( 2018-10-24), p. 848-
    Abstract: 〈 p class="abstract" 〉 〈 strong 〉 Background: 〈 /strong 〉 Adhesive capsulitis of should is also called frozen shoulder which describes a chronic, indolent pathological process in which the body forms excessive adhesions across the glenohumeral joint which in turn leads to pain, stiffness, and loss of range of movements which compromises the quality of life. The objective of the study was to evaluate the efficacy and functional outcome of autologous PRP injection and hydrodissection in adhesive capsulitis of shoulder. 〈 /p 〉 〈 p class="abstract" 〉 〈 strong 〉 Methods: 〈 /strong 〉 After excluding the patients who failed to satisfy the study protocol, the remaining 100 patients are divided equally into two groups namely group A (n=50) who receive autologous PRP injection and group B (n=50) who receive hydrodissection for adhesive capsulitis of shoulder. Both group participants are followed up pre-procedurally and post-procedurally at the end of 1 〈 sup 〉 st 〈 /sup 〉 , 6 〈 sup 〉 th 〈 /sup 〉 and 12 〈 sup 〉 th 〈 /sup 〉 month for pain relief and range of movements. The improvements in pain and range of movements are charted in terms of VAS and DASH scoring system. 〈 strong 〉 〈 /strong 〉 〈 /p 〉 〈 p class="abstract" 〉 〈 strong 〉 Results: 〈 /strong 〉 The statistical analysis were done for 46 patients in group A and 45 patients in group B which showed a statistical improvement in pain and range of movements (p & lt;0.001 for VAS score and p & lt;0.01 for DASH score) in group A who received autologous platelet rich plasma therapy. Autologous PRP therapy improves the functional quality of life with a long term outcome. 〈 /p 〉 〈 p class="abstract" 〉 〈 strong 〉 Conclusions: 〈 /strong 〉 For adhesive capsulitis of shoulder, autologous PRP therapy remains functionally superior than hydrodissection as autologous PRP is a constructive procedure by rejuvenating the degenerative tissues. 〈 /p 〉 〈 p 〉   〈 /p 〉
    Type of Medium: Online Resource
    ISSN: 2455-4510
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2018
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