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  • McGill University Library and Archives  (2)
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  • McGill University Library and Archives  (2)
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  • 1
    Online Resource
    Online Resource
    McGill University Library and Archives ; 2012
    In:  McGill Science Undergraduate Research Journal Vol. 7, No. 1 ( 2012-03-31), p. 28-34
    In: McGill Science Undergraduate Research Journal, McGill University Library and Archives, Vol. 7, No. 1 ( 2012-03-31), p. 28-34
    Abstract: Introduction: inferring genetic ancestry of different species is a current challenge in phylogenetics because of the immense raw biological data to be analyzed. computational techniques are necessary in order to parse and analyze all of such data in an efficient but accurate way, with many algorithms based on statistical principles designed to provide a best estimate of a phylogenetic topology. Methods: in this study, we analyzed a class of algorithms known as Markov Chain Monte Carlo (MCMC) algorithms, which uses Bayesian statistics on a biological model, and simulates the most likely evolutionary history through continuous random sampling. we combined this method with a python-based implementation on both artificially generated and actual sets of genetic data from the UCSC genome browser. results and discussion: we observe that MCMC methods provide a strong alternative to the more computationally intense likelihood algorithms and statistically weaker parsimony algorithms. given enough time, the MCMC algorithms will generate a phylogenetic tree that eventually converges to the most probable configuration
    Type of Medium: Online Resource
    ISSN: 1718-0783 , 1718-0775
    Language: Unknown
    Publisher: McGill University Library and Archives
    Publication Date: 2012
    detail.hit.zdb_id: 2418993-5
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  • 2
    Online Resource
    Online Resource
    McGill University Library and Archives ; 2013
    In:  McGill Science Undergraduate Research Journal Vol. 8, No. 1 ( 2013-03-31), p. 62-68
    In: McGill Science Undergraduate Research Journal, McGill University Library and Archives, Vol. 8, No. 1 ( 2013-03-31), p. 62-68
    Abstract: Modern cooperative software systems involve multiple concurrent users undertaking a common task in a real-time distributed environment, such as editing a shared text document. Maintaining data consistency, transaction causality, and replication convergence in such an environment, while providing fast client responsiveness, is a substantial challenge for classical distributed computing techniques. Operational transformation (OT) is a class of concurrency algorithms and data models that supports these functionalities, which has drawn significant research attention in the past decade. In this review, we discuss the basic components of operational transformation models, the algorithms involved, and their actual implementations in real-world networked systems. We compare several existing OT control algorithms, the transformation functions and properties supported by each of the algorithms, and the trade-offs that are made with respect to each one. The data and operational models used in OT are well suited for high- latency environments such as the Internet, making them more frequently used in modern web services. Although many different OT control algorithms exist, choosing the most effective one often depends on the particular operations that an application must support.
    Type of Medium: Online Resource
    ISSN: 1718-0783 , 1718-0775
    Language: Unknown
    Publisher: McGill University Library and Archives
    Publication Date: 2013
    detail.hit.zdb_id: 2418993-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
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