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  • MDPI AG  (15)
  • 1
    In: Applied Sciences, MDPI AG, Vol. 10, No. 16 ( 2020-08-11), p. 5553-
    Abstract: In this work, the ultrafast transient absorption spectroscopy (TAs) was utilized to first investigate the charge transfer from the emerging FAPbI3 (FA = CH(NH2)2) perovskite quantum dots (PQDs) to charge transport layers. Specifically, we compared the TAs in pure FAPbI3 PQDs, PQDs grown with both electron and hole transfer layers (ETL and HTL), and PQDs with only ETL or HTL. The TA signals induced by photoexcited electrons decay much faster in PQDs samples with the ETL (~20 ps) compared to the pure FAPbI3 PQDs ( 〉 1 ns). These results reveal that electrons can effectively transport between coupled PQDs and transfer to the ETL (TiO2) at a time scale of 20 ps, much faster than the bimolecular charge recombination inside the PQDs ( 〉 1 ns), and the electron transfer efficiency is estimated to be close to 100%. In contrast, the temporal evolution of the TA signals in the PQDs with and without HTL exhibit negligible change, and no substantive hole transfer to the HTL (poly[bis(4-phenyl)(2,4,6-trimethylphenyl)amine], PTAA) occurs within 1 ns. The much slower hole transfer implies the further potential of increasing the overall photo-carrier conversion efficiency through enhancing the hole diffusion length and fine-tuning the coupling between the HTL and PQDs.
    Type of Medium: Online Resource
    ISSN: 2076-3417
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2704225-X
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  • 2
    In: Genes, MDPI AG, Vol. 13, No. 9 ( 2022-09-03), p. 1581-
    Abstract: Objectives: The reprogramming of lipid metabolism is a new trait of cancers. However, the role of lipid metabolism in the tumor immune microenvironment (TIME) and the prognosis of gastric cancer remains unclear. Methods: Consensus clustering was applied to identify novel subgroups. ESTIMATE, TIMER, and MCPcounter algorithms were used to determine the TIME of the subgroups. The underlying mechanisms were elucidated using functional analysis. The prognostic model was established using the LASSO algorithm and multivariate Cox regression analysis. Results: Three molecular subgroups with significantly different survival were identified. The subgroup with relatively low lipid metabolic expression had a lower immune score and immune cells. The differentially expressed genes (DEGs) were concentrated in immune biological processes and cell migration via GO and KEGG analyses. GSEA analysis showed that the subgroups were mainly enriched in arachidonic acid metabolism. Gastric cancer survival can be predicted using risk models based on lipid metabolism genes. Conclusions: The TIME of gastric cancer patients is related to the expression of lipid metabolism genes and could be used to predict cancer prognosis accurately.
    Type of Medium: Online Resource
    ISSN: 2073-4425
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2527218-4
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  • 3
    In: Remote Sensing, MDPI AG, Vol. 15, No. 5 ( 2023-02-25), p. 1271-
    Abstract: On 2 January 2022, an earthquake of Ms 5.5 occurred in Ninglang County, Lijiang City, the earthquake-prone area of northwestern Yunnan. Whether this earthquake caused significant deformation and thermal anomalies and whether there is a relationship between them needs further investigation. Currently, multi-source remote sensing technology has become a powerful tool for long-time-series monitoring of earthquakes and active ruptures which mainly focuses on single crustal deformation and thermal anomaly. This study aims to reveal the crustal deformation and thermal anomaly characteristics of the Ninglang earthquake by using both Interferometric Synthetic Aperture Radar (InSAR) and Robust Satellite Techniques (RST). First, Sentinel-1A satellite SAR data were selected to obtain the coseismic deformation field based on Differential InSAR (D-InSAR), and the Small Baseline Set InSAR (SBAS-InSAR) technique was exploited to invert the pre- and post-earthquake displacement sequences. Then, RST was used to extract the thermal anomalies before and after the earthquake by using Moderate Resolution Imaging Spectroradiometer Land Surface Temperature (MODIS LST). The results indicate that the seismic crustal deformation is dominated by subsidence, with 23 thermal anomalies before and after the earthquake. It is speculated that the Yongning Fault in the deformation area is the main seismogenic fault of the Ninglang earthquake, which is dominated by positive fault dip-slip motion. Meanwhile, the seismic fault system composed of NE- and NW-oriented faults is an important factor in the formation of thermal anomalies, which are accompanied by changes in stress at different stages before and after the earthquake. Moreover, the crustal deformation and seismic thermal anomalies are correlated in time and space, and the active rupture activities in the region produce deformation accompanied by changes in thermal radiation. This study provides clues from remote sensing observations for analyzing the Ninglang earthquake and provides a reference for the joint application of InSAR and RST for earthquake monitoring.
    Type of Medium: Online Resource
    ISSN: 2072-4292
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2513863-7
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  • 4
    Online Resource
    Online Resource
    MDPI AG ; 2023
    In:  Water Vol. 15, No. 18 ( 2023-09-07), p. 3187-
    In: Water, MDPI AG, Vol. 15, No. 18 ( 2023-09-07), p. 3187-
    Abstract: Solute transport in aquifers is usually controlled by dynamic changes in groundwater tables. The influence mechanism of surface hydrological processes, especially precipitation, on solute transport under different water table conditions has not been studied much. Prior to the direct application of the existing solute transport mechanisms and models to the solute transport process, the following questions need to be addressed: (1) Do surface hydrological conditions (e.g., precipitation) cause changes in the gradient of the water table within a specific region? (2) If the gradient of the water table does change, how does the change influence solute transport and distribution in the aquifer? The objective of this study is to investigate how precipitation impacts the gradient of water table and to analyze how the solute transport is influenced by the change in the gradient of water table. To achieve this, we employed an analytical solute transport model for the time-varying gradient of a water table through continuous multipoint monitoring of the groundwater table data. Further, the model was applied to indoor experiments to simulate solute transport with and without precipitation. Finally, the mechanism of solute transport in the aquifer under the changing gradient of the water table was analyzed using mathematical and physical models, and the modeling results were compared with those from a numerical model to analyze the modeling reliability. The results showed that precipitation changed the previously stable gradient of the water table, which further altered the gradient of the water table and the transport path of the tracer. The tracer transport direction was primarily controlled by the flow direction in the sandy aquifer trough without precipitation. However, the route of the tracer transport was consistent with the direction of the change in the water table gradient due to precipitation. The small discrepancy between the results from the analytical and numerical models indicates that the model employed in this study is reliable.
    Type of Medium: Online Resource
    ISSN: 2073-4441
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2521238-2
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  • 5
    In: Applied Sciences, MDPI AG, Vol. 12, No. 3 ( 2022-01-21), p. 1101-
    Abstract: The influence of tillage and nitrogen fertilization methods on soil quality attributes and crop agronomic characteristics has been studied broadly under different agroclimatic conditions. Nevertheless, the interactive effect of tillage and fertilization approaches on soil properties on different soil depths and yield is rarely addressed, particularly on the Loess Plateau belt, and requires more exploration. Thus, this research was conducted in order to evaluate the interactive impact of tillage and nitrogen fertilization methods on soil properties and wheat productivity. The treatments included conventional tillage (CT) and no-till (NT) with different fertilization approaches (no fertilization: CK, chemical nitrogen fertilizer: N, organic fertilizer: M, combined application of nitrogen fertilizer and organic fertilizer: NM) and were explored in a split plot arrangement under a randomized complete block design replicated thrice on soil properties (SWC, SOC, TN, TP, NO3−-N, NH4+-N, and stoichiometric ratio) and wheat yield. The results showed that sole no-tillage and NT in association with nitrogen fertilization (inorganic and organic) significantly increased the soil water content, SOC, TN, NH4+-N, C/P, and N/P ratios and wheat productivity but did not significantly yield TP, whilst it reduced the NO3−-N and C/N ratio compared with sole CT and CT together with nitrogen fertilization (organic and inorganic). Overall, NT in association with the joint application of inorganic and organic N fertilization are the best techniques to improve soil water status and nutrient status under the wheat mono-cropping system conditions and yield.
    Type of Medium: Online Resource
    ISSN: 2076-3417
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2704225-X
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  • 6
    In: Sensors, MDPI AG, Vol. 19, No. 12 ( 2019-06-22), p. 2806-
    Abstract: The Chang’e-4 (CE-4) lunar rover, equipped with a visible and near-IR imaging spectrometer (VNIS) based on acousto-optic tunable filter spectroscopy, was launched to the far side of the moon on December 8, 2018. The detection band of the VNIS ranges from 0.45 to 2.4 μm. Because of the weak reflection of infrared radiation from the lunar surface, a static electronic phase-locked acquisition method is adopted in the infrared channel for signal amplification. In this paper, full-link simulations and modeling are conducted on the infrared channel information flow of the instrument. The signal characteristics of the VNIS are analyzed in depth, and the signal to noise ratio (SNR) prediction and laboratory verification are presented. On 4 January 2019, the VNIS started working successfully and acquired high-resolution spectrum data of the far side of the moon for the first time. Through analysis we have found that the SNR ratio is in line with our predictions, and the data obtained by VNIS in orbit are consistent with the information model proposed in this paper.
    Type of Medium: Online Resource
    ISSN: 1424-8220
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2052857-7
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  • 7
    Online Resource
    Online Resource
    MDPI AG ; 2022
    In:  Genes Vol. 13, No. 6 ( 2022-05-31), p. 993-
    In: Genes, MDPI AG, Vol. 13, No. 6 ( 2022-05-31), p. 993-
    Abstract: Ovarian cancer (OC) is one of the most common gynecological malignancies. It is associated with a difficult diagnosis and poor prognosis. Our study aimed to analyze tumor stemness to determine the prognosis feature of patients with OC. At this job, we selected the gene expression and the clinical profiles of patients with OC in the TCGA database. We calculated the stemness index of each patient using the one-class logistic regression (OCLR) algorithm and performed correlation analysis with immune infiltration. We used consensus clustering methods to classify OC patients into different stemness subtypes and compared the differences in immune infiltration between them. Finally, we established a prognostic signature by Cox and LASSO regression analysis. We found a significant negative correlation between a high stemness index and immune score. Pathway analysis indicated that the differentially expressed genes (DEGs) from the low- and high-mRNAsi groups were enriched in multiple functions and pathways, such as protein digestion and absorption, the PI3K-Akt signaling pathway, and the TGF-β signaling pathway. By consensus cluster analysis, patients with OC were split into two stemness subtypes, with subtype II having a better prognosis and higher immune infiltration. Furthermore, we identified 11 key genes to construct the prognostic signature for patients with OC. Among these genes, the expression levels of nine, including SFRP2, MFAP4, CCDC80, COL16A1, DUSP1, VSTM2L, TGFBI, PXDN, and GAS1, were increased in the high-risk group. The analysis of the KM and ROC curves indicated that this prognostic signature had a great survival prediction ability and could independently predict the prognosis for patients with OC. We established a stemness index-related risk prognostic module for OC, which has prognostic-independent capabilities and is expected to improve the diagnosis and treatment of patients with OC.
    Type of Medium: Online Resource
    ISSN: 2073-4425
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2527218-4
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  • 8
    Online Resource
    Online Resource
    MDPI AG ; 2023
    In:  Applied Sciences Vol. 13, No. 3 ( 2023-02-02), p. 1943-
    In: Applied Sciences, MDPI AG, Vol. 13, No. 3 ( 2023-02-02), p. 1943-
    Abstract: The existing literature mainly focuses on the research of reinforced concrete (RC) beams under a single load such as blast or impact. In this paper, the slab–rib–slab RC beam, a new type of structure widely used in bridge structures, was taken as the research object. The explicit dynamic analysis software LS-DYNA was used to numerically analyze the dynamic response and failure behavior of I-shaped RC beams under combined blast and impact loads. For this reason, an effective numerical analysis model was obtained by carrying out experiments on I-shaped RC beams under contact explosion. The key factors affecting the dynamic response of the structure under combined loads were numerically analyzed. Numerical results showed that different load application sequences have important effects on the dynamic response of the structure. When the impact load was first applied to the structure, more severe concrete damage and deformation occured in the depth direction of the beam. However, when the blast load was first applied to the structure, the concrete at the lower flange was damaged in the span direction of the beam due to tension, and no large-scale concrete spallation occurred in the depth direction. This was mainly due to the different mechanisms of blast and impact loads. In addition, the vulnerability of the I-shaped RC beams varied with some structural parameters, including span, depth, and configuration of reinforcement. At the same time, the results showed that the structure is more sensitive to changes in structural parameters when it is first subjected to impact loads.
    Type of Medium: Online Resource
    ISSN: 2076-3417
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
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  • 9
    In: Sensors, MDPI AG, Vol. 22, No. 15 ( 2022-07-28), p. 5645-
    Abstract: Data are a strategic resource for industrial production, and an efficient data-mining process will increase productivity. However, there exist many missing values in data collected in real life due to various problems. Because the missing data may reduce productivity, missing value imputation is an important research topic in data mining. At present, most studies mainly focus on imputation methods for continuous missing data, while a few concentrate on discrete missing data. In this paper, a discrete missing value imputation method based on a multilayer perceptron (MLP) is proposed, which employs a momentum gradient descent algorithm, and some prefilling strategies are utilized to improve the convergence speed of the MLP. To verify the effectiveness of the method, experiments are conducted to compare the classification accuracy with eight common imputation methods, such as the mode, random, hot-deck, KNN, autoencoder, and MLP, under different missing mechanisms and missing proportions. Experimental results verify that the improved MLP model (IMLP) can effectively impute discrete missing values in most situations under three missing patterns.
    Type of Medium: Online Resource
    ISSN: 1424-8220
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2052857-7
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  • 10
    In: Sensors, MDPI AG, Vol. 19, No. 7 ( 2019-04-08), p. 1667-
    Abstract: Wide Swath and High Resolution Airborne Pushbroom Hyperspectral Imager (WiSHiRaPHI) is the new-generation airborne hyperspectral imager instrument of China, aimed at acquiring accurate spectral curve of target on the ground with both high spatial resolution and high spectral resolution. The spectral sampling interval of WiSHiRaPHI is 2.4 nm and the spectral resolution is 3.5 nm (FWHM), integrating 256 channels coving from 400 nm to 1000 nm. The instrument has a 40-degree field of view (FOV), 0.125 mrad instantaneous field of view (IFOV) and can work in high spectral resolution mode, high spatial resolution mode and high sensitivity mode for different applications, which can adapt to the Velocity to Height Ratio (VHR) lower than 0.04. The integration has been finished, and several airborne flight validation experiments have been conducted. The results showed the system’s excellent performance and high efficiency.
    Type of Medium: Online Resource
    ISSN: 1424-8220
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2052857-7
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