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  • 1
    Online Resource
    Online Resource
    Facile Synthesis of Carboxymethyl Cellulose Coated Core/Shell SiO2@Cu Nanoparticles and Their Antifungal Activity against Phytophthora capsici
    MDPI AG ; 2021
    In:  Polymers Vol. 13, No. 6 ( 2021-03-14), p. 888-
    Details
    In: Polymers, MDPI AG, Vol. 13, No. 6 ( 2021-03-14), p. 888-
    Abstract: Cu nanoparticles are a potential material for creating novel alternative antimicrobial products due to their unique antibacterial/antifungal properties, stability, dispersion, low cost and abundance as well as being economical and ecofriendly. In this work, carboxymethyl cellulose coated core/shell SiO2@Cu nanoparticles (NPs) were synthesized by a simple and effective chemical reduction process. The initial SiO2 NPs, which were prepared from rice husk ash, were coated by a copper ultrathin film using hydrazine and carboxymethyl cellulose (CMC) as reducing agent and stable agent, respectively. The core/shell SiO2@Cu nanoparticles with an average size of ~19 nm were surrounded by CMC. The results indicated that the SiO2@Cu@CMC suspension was a homogenous morphology with a spherical shape, regular dispersion and good stability. Furthermore, the multicomponent SiO2@Cu@CMC NPs showed good antifungal activity against Phytophthora capsici (P. capsici). The novel Cu NPs-based multicomponent suspension is a key compound in the development of new fungicides for the control of the Phytophthora disease.
    Type of Medium: Online Resource
    ISSN: 2073-4360
    URL: Article
    DOI: 10.3390/polym13060888
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2527146-5
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  • 2
    Online Resource
    Online Resource
    The Drought-Mediated Soybean GmNAC085 Functions as a Positive Regulator of Plant Response to Salinity
    MDPI AG ; 2021
    In:  International Journal of Molecular Sciences Vol. 22, No. 16 ( 2021-08-20), p. 8986-
    Details
    In: International Journal of Molecular Sciences, MDPI AG, Vol. 22, No. 16 ( 2021-08-20), p. 8986-
    Abstract: Abiotic stress factors, such as drought and salinity, are known to negatively affect plant growth and development. To cope with these adverse conditions, plants have utilized certain defense mechanisms involved in various aspects, including morphological, biochemical and molecular alterations. Particularly, a great deal of evidence for the biological importance of the plant-specific NAM, ATAF1/2, CUC2 (NAC) transcription factors (TFs) in plant adaptation to abiotic stress conditions has been reported. A previous in planta study conducted by our research group demonstrated that soybean (Glycine max) GmNAC085 mediated drought resistance in transgenic Arabidopsis plants. In this study, further characterization of GmNAC085 function in association with salt stress was performed. The findings revealed that under this condition, transgenic soybean plants overexpressing GmNAC085 displayed better germination rates than wild-type plants. In addition, biochemical and transcriptional analyses showed that the transgenic plants acquired a better defense system against salinity-induced oxidative stress, with higher activities of antioxidant enzymes responsible for scavenging hydrogen peroxide or superoxide radicals. Higher transcript levels of several key stress-responsive genes involved in the proline biosynthetic pathway, sodium ion transporter and accumulation of dehydrins were also observed, indicating better osmoprotection and more efficient ion regulation capacity in the transgenic lines. Taken together, these findings and our previous report indicate that GmNAC085 may play a role as a positive regulator in plant adaptation to drought and salinity conditions.
    Type of Medium: Online Resource
    ISSN: 1422-0067
    URL: Article
    DOI: 10.3390/ijms22168986
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2019364-6
    SSG: 12
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  • 3
    Online Resource
    Online Resource
    Serum Uric Acid Levels and Risk of Rapid Decline of Estimated Glomerular Filtration Rate in Patients with Type 2 Diabetes: Findings from a 5-Year Prospective Cohort Study
    MDPI AG ; 2021
    In:  Healthcare Vol. 9, No. 10 ( 2021-10-09), p. 1341-
    Details
    In: Healthcare, MDPI AG, Vol. 9, No. 10 ( 2021-10-09), p. 1341-
    Abstract: This study investigated the association between serum uric acid (SUA) levels with rapid decline of the estimated glomerular filtration rate (eGFR) in type 2 diabetes (T2 DM) patients. A prospective cohort study was conducted in a community-based hospital in Vietnam. We followed 405 T2DM patients with normal kidney function for five years. Rapid progression of kidney function was defined as an average annual decrease of eGFR of at least 4 mL/min/1.73 m2 and was found in 16.0% of patients. Patients in the SUA high tertile ( ≥6 mg/dL) had higher BMI (p = 0.004), lower HbA1c (p = 0.001), lower eGFR (p 〈 0.001) and higher rate of hypertension than low and middle tertile. After adjusting for age and sex, rapid progression of renal function was significantly associated with SUA level (OR = 1.22, 95% CI 1.02–1.45, p = 0.026). This association was marginally significant when more covariates were included in the model (OR = 1.20, 95% CI 0.99–1.46, p = 0.065). However, the association between tertiles of SUA and rapid decline of eGFR was not statistically significant. This study demonstrates neither a strong significant association between SUA and rapid decline of eGFR nor evidence to refuse the role of SUA levels in the increased risk of renal function decline in in T2DM patients.
    Type of Medium: Online Resource
    ISSN: 2227-9032
    URL: Article
    DOI: 10.3390/healthcare9101341
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2721009-1
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  • 4
    Online Resource
    Online Resource
    Numerical Simulation of the Flood and Inundation Caused by Typhoon Noru Downstream from the Vu Gia-Thu Bon River Basin
    MDPI AG ; 2023
    In:  Sustainability Vol. 15, No. 10 ( 2023-05-18), p. 8203-
    Details
    In: Sustainability, MDPI AG, Vol. 15, No. 10 ( 2023-05-18), p. 8203-
    Abstract: Typhoon Noru (2022) was a historic storm that caused significant damage to the central region of Vietnam. Typhoon Noru has caused strong winds and torrential rainfall in Da Nang, Quang Nam, and Quang Ngai. Quang Nam Province saw many trees and power lines fall, and many areas were flooded. The Da Nang government has reported the typhoon toppled many trees, blew the rooftops of three houses, damaged the walls of several schools, and caused a power outage at some 3200 substations. It resulted in widespread flooding in coastal areas and downstream from the Vu Gia-Thu Bon River river basin. This study evaluates the impact of Typhoon Noru. The results show that: (1) The numerical simulation was applied to re-analyze the offshore meteorological field with the Coupled Ocean–Atmosphere–Wave–Sediment Transport (COAWST) model as an input for 2D wave propagation and hydraulic models; (2) The study couples the 1D and 2D models in MIKE FLOOD to simulate the flood and inundation caused by Typhoon Noru in the study area. The calibration and validation results of the 1D hydraulic model, the 2D wave propagation model, and the 2D hydrodynamic model were reasonably good, with a Nash coefficient ranging from 0.84 to 0.96 and a percent bias (BIAS) of −0.9% to 7.5%. The results of the simulation showed that the flood and inundation caused by Typhoon Noru resulted in significant damage in two districts: Thang Binh in Quang Nam province and Hoa Vang in Da Nang province. The practical significance of these results is that they provide valuable support for warning systems and troubleshooting efforts related to the impact of typhoons.
    Type of Medium: Online Resource
    ISSN: 2071-1050
    URL: Article
    DOI: 10.3390/su15108203
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2518383-7
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  • 5
    Online Resource
    Online Resource
    Nonlinear Stability Analysis of Eccentrically Stiffened Functionally Graded Truncated Conical Sandwich Shells with Porosity
    MDPI AG ; 2018
    In:  Materials Vol. 11, No. 11 ( 2018-11-06), p. 2200-
    Details
    In: Materials, MDPI AG, Vol. 11, No. 11 ( 2018-11-06), p. 2200-
    Abstract: : This paper analyzes the nonlinear buckling and post-buckling characteristics of the porous eccentrically stiffened functionally graded sandwich truncated conical shells resting on the Pasternak elastic foundation subjected to axial compressive loads. The core layer is made of a porous material (metal foam) characterized by a porosity coefficient which influences the physical properties of the shells in the form of a harmonic function in the shell’s thickness direction. The physical properties of the functionally graded (FG) coatings and stiffeners depend on the volume fractions of the constituents which play the role of the exponent in the exponential function of the thickness direction coordinate axis. The classical shell theory and the smeared stiffeners technique are applied to derive the governing equations taking the von Kármán geometrical nonlinearity into account. Based on the displacement approach, the explicit expressions of the critical buckling load and the post-buckling load-deflection curves for the sandwich truncated conical shells with simply supported edge conditions are obtained by applying the Galerkin method. The effects of material properties, core layer thickness, number of stiffeners, dimensional parameters, semi vertex angle and elastic foundation on buckling and post-buckling behaviors of the shell are investigated. The obtained results are validated by comparing with those in the literature.
    Type of Medium: Online Resource
    ISSN: 1996-1944
    URL: Article
    DOI: 10.3390/ma11112200
    Language: English
    Publisher: MDPI AG
    Publication Date: 2018
    detail.hit.zdb_id: 2487261-1
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  • 6
    Online Resource
    Online Resource
    Identifying Flow Eddy Currents in the River System as the Riverbank Scouring Cause: A Case Study of the Mekong River
    MDPI AG ; 2022
    In:  Water Vol. 14, No. 15 ( 2022-08-04), p. 2418-
    Details
    In: Water, MDPI AG, Vol. 14, No. 15 ( 2022-08-04), p. 2418-
    Abstract: River morphological change is the complex evolution of riverbed states, which can lead to serious riverbank failures, and is a worldwide concern. However, revealing the cause of the evolution, in particular, the potential morphological scouring by eddy currents, is difficult. Accordingly, we propose a comprehensive combination of 2D and 3D simulations to reveal the eddy currents. We selected the Vam Nao, part of the Mekong River, with semi-tidal effects and confluence flows as the case study. We created two unstructured 40 m × 40 m triangular meshes using inverse distance interpolation. This study used the Saint–Venant equations (TELEMAC2D) and Navier–Stokes equations (TELEMAC3D) to reveal the eddy currents for 2009, 2017, and 2018. TELEMAC2D (the simplified form of TELEMAC3D) was assessed for 15 days, 3 months, and 1 year, which met a satisfactory level. The eddy currents’ appearance was verified by local knowledge. We found recirculating currents near the riverbank to the East (right at the riverbank failures), whose velocity was approximately half and 1/3–1/4 of the mainstream flow velocity in the dry and flood seasons, respectively. Our study approach performed well in revealing the eddy currents, which can aid in assessing potential riverbank failures and can be applicable to similar contexts.
    Type of Medium: Online Resource
    ISSN: 2073-4441
    URL: Article
    DOI: 10.3390/w14152418
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2521238-2
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  • 7
    Online Resource
    Online Resource
    Functional Nanostructured Oligochitosan–Silica/ Carboxymethyl Cellulose Hybrid Materials: Synthesis and Investigation of Their Antifungal Abilities
    MDPI AG ; 2019
    In:  Polymers Vol. 11, No. 4 ( 2019-04-04), p. 628-
    Details
    In: Polymers, MDPI AG, Vol. 11, No. 4 ( 2019-04-04), p. 628-
    Abstract: Functional hybrid materials were successfully synthesized from low-cost waste products, such as oligochitosan (OCS) obtained from chitosan (one of the main components in crab shells) and nanosilica (nSiO2) obtained from rice husk, in a 1:1 ratio (w/w), and their dispersion in the presence of carboxymethyl cellulose at pH 7 was stable for over one month without aggregation. The molecular weights, chemical structures, morphologies, and crystallinities of the obtained materials were characterized by GPC, FTIR, TEM, and XRD, respectively. The antifungal effects of OCS, nSiO2, and the OCS/nSiO2 hybrid materials were investigated via a disk-diffusion method. The results showed that the nanohybrid materials had better resistance to Phytophthora infestans fungus than the individual components, and a concentration of the OCS2/nSiO2 hybrid material of 800 mg L−1 was the lowest concentration where the material completely inhibited Phytophthora infestans growth, as measured via an agar dilution method. This study not only creates a novel environmentally friendly material with unique synergistic effects that can replace current toxic agrochemicals but also can be considered a new platform for further research in green agricultural applications.
    Type of Medium: Online Resource
    ISSN: 2073-4360
    URL: Article
    DOI: 10.3390/polym11040628
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2527146-5
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  • 8
    Online Resource
    Online Resource
    COVID-19 and Sickle Cell Disease in the Province of Quebec, Canada: Outcomes after Two Years of the Pandemic
    MDPI AG ; 2022
    In:  Journal of Clinical Medicine Vol. 11, No. 24 ( 2022-12-12), p. 7361-
    Details
    In: Journal of Clinical Medicine, MDPI AG, Vol. 11, No. 24 ( 2022-12-12), p. 7361-
    Abstract: Background: Patients with sickle cell disease (SCD) are considered at higher risk of severe COVID-19 infection. However, morbidity and mortality rates are variable among countries. To date, there are no published reports that document outcomes of SCD patients with COVID-19 in Canada. Methods: A web-based registry was implemented in June 2020 capturing outcomes of SCD patients with COVID-19 from March 2020 to April 2022 and comparing them to the general population of Quebec, Canada. Results: After 24 months of the pandemic, 185 SCD patients with confirmed SARS-CoV-2 infection were included in the registry. Overall, the population was young (median age 12 years old) and had few comorbidities. No deaths were reported. Risk of hospitalization and admission to intensive care unit (ICU) because of COVID-19 was higher in patients with SCD than in the general population (relative risks (RR) 5.15 (95% confidence interval (95% CI) 3.84–6.91), p ˂ 0.001 and 4.56 (95% CI 2.09–9.93) p ˂ 0.001). A history of arterial hypertension or acute chest syndrome in the past 12 months was associated with a higher risk of severe disease (RR = 3.06 (95% CI 1.85–5.06) p = 0.008 and 2.27 (95% CI 1.35–3.83) p = 0.01). Hospitalized patients had lower hemoglobin F than non-hospitalized patients (12% vs. 17%, p = 0.02). For those who had access to vaccination at the time of infection, 25 out of 26 patients were adequately vaccinated and had mild disease. Conclusions: The SCD population is at higher risk of severe disease than the general population. However, we report favorable outcomes as no deaths occurred. Registries will continue to be critical to document the impact of novel COVID-19 specific therapy and vaccines for the SCD population.
    Type of Medium: Online Resource
    ISSN: 2077-0383
    URL: Article
    DOI: 10.3390/jcm11247361
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662592-1
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  • 9
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    Online Resource
    Predictors of eHealth Literacy and Its Associations with Preventive Behaviors, Fear of COVID-19, Anxiety, and Depression among Undergraduate Nursing Students: A Cross-Sectional Survey
    MDPI AG ; 2022
    In:  International Journal of Environmental Research and Public Health Vol. 19, No. 7 ( 2022-03-22), p. 3766-
    Details
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 19, No. 7 ( 2022-03-22), p. 3766-
    Abstract: Background: The infodemic has been co-existing with the COVID-19 pandemic with an influx of misinformation and conspiracy theories. These affect people’s psychological health and adherence to preventive measures. eHealth literacy (eHEALS) may help with alleviating the negative effects of the infodemic. As nursing students are future healthcare professionals, having adequate eHEALS skills is critically important in their clinical practice, safety, and health. This study aimed to (1) explore the eHEALS level and its associated factors, and (2) examine the associations of eHEALS with preventive behaviors, fear of COVID-19 (FCV-19S), anxiety, and depression among nursing students. Methods: We surveyed 1851 nursing students from 7 April to 31 May 2020 from eight universities across Vietnam. Data were collected, including demographic characteristics, eHEALS, adherence to preventive behaviors (handwashing, mask-wearing, physical distancing), FCV-19S, anxiety, and depression. Linear and logistic regression analyses were performed appropriately to examine associations. Results: The mean score of eHEALS was 31.4 ± 4.4. The eHEALS score was significantly higher in males (unstandardized regression coefficient, B, 0.94; 95% confidence interval, 95% CI, 0.15 to 1.73; p = 0.019), and students with a better ability to pay for medication (B, 0.79; 95% CI, 0.39 to 1.19; p 〈 0.001), as compared to their counterparts. Nursing students with a higher eHEALS score had a higher likelihood of adhering to hand-washing (odds ratio, OR, 1.18; 95% CI, 1.15 to 1.22; p 〈 0.001), mask-wearing (OR, 1.15; 95% CI, 1.12 to 1.19; p 〈 0.001), keeping a safe physical distance (OR, 1.20; 95% CI, 1.15 to 1.25; p 〈 0.001), and had a lower anxiety likelihood (OR, 0.95; 95% CI, 0.92 to 0.99; p = 0.011). Conclusions: Nursing students who were men and with better ability to pay for medication had higher eHEALS scores. Those with higher eHEALS scores had better adherence to preventive measures, and better psychological health. The development of strategies to improve eHEALS of nursing students may contribute to COVID-19 containment and improve their psychological health.
    Type of Medium: Online Resource
    ISSN: 1660-4601
    URL: Article
    DOI: 10.3390/ijerph19073766
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2175195-X
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