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  • MDPI AG  (20)
  • 1
    Online-Ressource
    Online-Ressource
    Assessment of BIM Competencies and Correlation Analysis between Competencies and Career Characteristics of FAB Construction Project Participants
    MDPI AG ; 2021
    In:  Applied Sciences Vol. 11, No. 18 ( 2021-09-13), p. 8468-
    Details
    In: Applied Sciences, MDPI AG, Vol. 11, No. 18 ( 2021-09-13), p. 8468-
    Kurzfassung: Currently, BIM implementation in domestic FAB construction projects is in such an early stage that they are benchmarking the BIM implementation method applied in the conventional building sector. As such, in order to enhance the usability of BIM in FAB construction projects, it is necessary to have a correct understanding of FAB construction and to apply BIM in accordance with the characteristics of FAB. This requires defining critical BIM competencies needed by the participants of FAB construction projects in undertaking their tasks as well as identifying their current level of competency possessed. Accordingly, this study defined and presented BIM competencies that reflect the characteristics of FAB through the analysis of typical tasks related to FAB construction projects. For this, project participants from three FAB construction project sites in Korea (where BIM was implemented) were recruited, and a survey was conducted on their status of competency level. Moreover, a comparative analysis was conducted focusing on the correlations between their career characteristics (‘Construction project experience’, ‘BIM-based construction project experience’, ‘FAB construction project experience’, ‘BIM-based FAB construction project experience’ and ‘Overall project experiences’) and their current level of BIM competencies. As a result, high correlations were found between BIM competencies and BIM-based FAB construction project experience for the owner group, whereas competency items related to BIM-based construction project experience showed high correlations for the designer group.
    Materialart: Online-Ressource
    ISSN: 2076-3417
    URL: Article
    DOI: 10.3390/app11188468
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2021
    ZDB Id: 2704225-X
    Standort Signatur Einschränkungen Verfügbarkeit
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    Online-Ressource
  • 2
    Online-Ressource
    Online-Ressource
    Dual Molecular Design toward a Lysosome-Tagged AIEgen and Heavy-Atom-Free Photosensitizers for Hypoxic Cancer Photodynamic Therapy
    MDPI AG ; 2022
    In:  Biosensors Vol. 12, No. 6 ( 2022-06-15), p. 420-
    Details
    In: Biosensors, MDPI AG, Vol. 12, No. 6 ( 2022-06-15), p. 420-
    Kurzfassung: To date, a large number of photosensitizers (PS) have introduced heavy atoms to improve the ISC process and 1O2 generation. However, they often show low efficiency in hypoxic conditions, aggregate states, and turn-off PDT in the dark. Besides that, the toxicity of heavy metals is also concerned. Therefore, we developed lysosome-targeted heavy-metal-free PS (3S and 4S) based on thionated naphthalimide for hypoxic cancer photodynamic therapy (PDT), not only under white light but also in the dark via thermal-induced 1O2 generation. AIEgen (3O and 4O) were prepared for studying the PDT action of PSs (3S and 4S) in lysosome and aggregate state. We also examined the photophysical properties of AIEgen (3O and 4O) and PS (3S and 4S) by UV–vis absorption, fluorescent emission spectra, and theoretical calculations.
    Materialart: Online-Ressource
    ISSN: 2079-6374
    URL: Article
    DOI: 10.3390/bios12060420
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2022
    ZDB Id: 2662125-3
    Standort Signatur Einschränkungen Verfügbarkeit
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    Online-Ressource
  • 3
    Online-Ressource
    Online-Ressource
    A Study on Emotions to Improve the Quality of Life of South Korean Senior Patients Residing in Convalescent Hospitals
    MDPI AG ; 2022
    In:  International Journal of Environmental Research and Public Health Vol. 19, No. 21 ( 2022-11-04), p. 14480-
    Details
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 19, No. 21 ( 2022-11-04), p. 14480-
    Kurzfassung: This study examined the occurrence of emotion types and the contents and meanings of individual emotion types to improve the quality of life of South Korean senior patients in convalescent hospitals. This research is a sequential mixed study in which we conducted emotion frequency and content analyses with 20 elderly resident patients in a convalescent hospital. In the emotion frequency analysis, we performed emotion occurrence frequency analysis and clustering to create groups of subjects that showed similar distributions of emotions. The study results found that South Korean senior patients displayed six major emotions: joy, sorrow, anger, surprise, fear, and tranquility, including mixed emotional states. In the emotion content analysis, we used NVivo to categorize and analyze the interview contents based on emotion types. The study results show the characteristics of emotions according to patients’ treatment and recovery, life within narrow boundaries, relationships with new people and family, and the appearances of themselves that they could not easily but must accept. In addition, these characteristics appeared in health, environment, relationships, and psychological structures. Ultimately, the study results suggest that improving the quality of life of South Korean senior patients requires understanding of their emotions and examining diverse emotions in multiple dimensions.
    Materialart: Online-Ressource
    ISSN: 1660-4601
    URL: Article
    DOI: 10.3390/ijerph192114480
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2022
    ZDB Id: 2175195-X
    Standort Signatur Einschränkungen Verfügbarkeit
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    Online-Ressource
  • 4
    Online-Ressource
    Online-Ressource
    The Relationship between Career Decision-Making Self-Efficacy, Career Preparation Behaviour and Career Decision Difficulties among South Korean College Students
    MDPI AG ; 2022
    In:  Sustainability Vol. 14, No. 21 ( 2022-11-03), p. 14384-
    Details
    In: Sustainability, MDPI AG, Vol. 14, No. 21 ( 2022-11-03), p. 14384-
    Kurzfassung: Few studies have continuously examined the relationship between career decision-making self-efficacy variables and career-related variables in South Korea’s specific cultural context. Accordingly, this study aims to analyse (using Pearson’s correlations and structural equation modelling) the relationships between South Korean college students’ career decision-making self-efficacy, career preparation behaviour, and career decision difficulties. There were positive and negative relationships between career decision-making self-efficacy and career preparation behaviour career decision difficulties, respectively. In addition, we found a positive effect between career preparation behaviour and career decision-making self-efficacy, while career decision difficulties negatively affected career decision-making self-efficacy. Considering the standardised coefficient of the specific direct effect, the effect on career decision-making self-efficacy of career preparation behaviour was larger than that of career decision difficulties. It is recommended that career programmes are developed that help college students to independently set their career goals, actively search for career information, and promote career preparation behaviour while considering their majors. It is also recommended career counselling programmes be designed that can help them establish their self-concept and identity. These findings could provide the necessary basic data for the construction of an effective college career guidance system and inform strategies for improving college students’ career decision-making self-efficacy.
    Materialart: Online-Ressource
    ISSN: 2071-1050
    URL: Article
    DOI: 10.3390/su142114384
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2022
    ZDB Id: 2518383-7
    Standort Signatur Einschränkungen Verfügbarkeit
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    Online-Ressource
  • 5
    Online-Ressource
    Online-Ressource
    Methyl Syringate Stimulates Glucose Uptake by Inhibiting Protein Tyrosine Phosphatases Relevant to Insulin Resistance
    MDPI AG ; 2023
    In:  Life Vol. 13, No. 6 ( 2023-06-12), p. 1372-
    Details
    In: Life, MDPI AG, Vol. 13, No. 6 ( 2023-06-12), p. 1372-
    Kurzfassung: Several protein tyrosine phosphatases (PTPs), particularly PTPN1, PTPN2, PTPN6, PTPN9, PTPN11, PTPRS, and DUSP9, are involved in insulin resistance. Therefore, these PTPs could be promising targets for the treatment of type 2 diabetes. Our previous studies revealed that PTPN2 and PTPN6 are potential antidiabetic targets. Therefore, the identification of dual-targeting inhibitors of PTPN2 and PTPN6 could be a potential therapeutic strategy for the treatment or prevention of type 2 diabetes. In this study, we demonstrate that methyl syringate inhibits the catalytic activity of PTPN2 and PTPN6 in vitro, indicating that methyl syringate acts as a dual-targeting inhibitor of PTPN2 and PTPN6. Furthermore, methyl syringate treatment significantly increased glucose uptake in mature 3T3-L1 adipocytes. Additionally, methyl syringate markedly enhanced phosphorylation of adenosine monophosphate-activated protein kinase (AMPK) in 3T3L1 adipocytes. Taken together, our results suggest that methyl syringate, a dual-targeting inhibitor of PTPN2 and PTPN6, is a promising therapeutic candidate for the treatment or prevention of type 2 diabetes.
    Materialart: Online-Ressource
    ISSN: 2075-1729
    URL: Article
    DOI: 10.3390/life13061372
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2023
    ZDB Id: 2662250-6
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 6
    Online-Ressource
    Online-Ressource
    Effect of Sevoflurane on the Proliferation of A549 Lung Cancer Cells
    MDPI AG ; 2023
    In:  Medicina Vol. 59, No. 3 ( 2023-03-20), p. 613-
    Details
    In: Medicina, MDPI AG, Vol. 59, No. 3 ( 2023-03-20), p. 613-
    Kurzfassung: Background and Objectives: Sevoflurane has opposing effects on cancer progression, depending on its concentration and the cancer type. This study investigated the effects of sevoflurane on the proliferation of A549 lung cancer cells. Materials and Methods: In vitro, the number of A549 cells exposed to different concentrations of sevoflurane was counted. The size and weight of tumors from a xenograft mouse model exposed to air or sevoflurane were measured in vivo experiments. Additionally, hematoxylin and eosin staining and immunohistochemical detection of Ki-67 in the harvested tumor tissues were performed. Results: A total of 72 culture dishes were used and 24 dishes were assigned to each group: Air group; 2% Sevo group (air + 2% sevoflurane); and 4% Sevo group (air + 4% sevoflurane). The number of A549 cells in the 2% Sevo group was less than that in the Air and 4% Sevo groups (Air: 7.9 ± 0.5; 0.5, 2% Sevo: 6.8 ± 0.4, 4% Sevo: 8.1 ± 0.3; p = 0.000). The tumor size was not significantly different between the two groups (Air: 1.5 ± 0.7, 2% Sevo: 2.4 ± 1.9; p = 0.380). Conclusions: The in vitro data showed that sevoflurane inhibited the proliferation of A549 lung cancer cells in a concentration-specific manner. However, the in vivo data showed no correlation between sevoflurane exposure and A549 cell proliferation. Thus, further research is required to understand fully the effects of sevoflurane on cancer progression and to reconcile differences between the in vitro and in vivo experimental results.
    Materialart: Online-Ressource
    ISSN: 1648-9144
    URL: Article
    DOI: 10.3390/medicina59030613
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2023
    ZDB Id: 2088820-X
    Standort Signatur Einschränkungen Verfügbarkeit
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    Online-Ressource
  • 7
    Online-Ressource
    Online-Ressource
    A Systematic Review and Meta-Analysis of the Effectiveness of Non-Face-to-Face Coaching
    MDPI AG ; 2023
    In:  Sustainability Vol. 15, No. 12 ( 2023-06-18), p. 9727-
    Details
    In: Sustainability, MDPI AG, Vol. 15, No. 12 ( 2023-06-18), p. 9727-
    Kurzfassung: This study examined the effectiveness of non-face-to-face coaching in South Korea in order to present alternatives in the post-COVID-19 environment. The research collected domestic studies on non-face-to-face coaching in South Korea and analysed the studies through a systematic literature review and meta-analysis. Among 1081 papers retrieved from the database, we selected ten papers for meta-analysis. Using the random effect model to measure effect size, the total effect size of non-face-to-face coaching was 0.77. When we divided the effect of non-face-to-face coaching into psychological, cognitive, and physical effects, the cognitive effects were the largest. In addition, examining non-face-to-face coaching by type resulted in a larger effect size of web-based online coaching in comparison to telephone coaching. By contrast, the effect sizes of non-face-to-face coaching by subject had the largest effect size on subjects with the highest level of vulnerability. This study found that non-face-to-face coaching had a large effect, with relatively large cognitive and psychological effects. Future investigations should supplement the present research through follow-up studies on non-face-to-face coaching.
    Materialart: Online-Ressource
    ISSN: 2071-1050
    URL: Article
    DOI: 10.3390/su15129727
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2023
    ZDB Id: 2518383-7
    Standort Signatur Einschränkungen Verfügbarkeit
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    Online-Ressource
  • 8
    Online-Ressource
    Online-Ressource
    Park Accessibility Impacts Housing Prices in Seoul
    MDPI AG ; 2017
    In:  Sustainability Vol. 9, No. 2 ( 2017-01-27), p. 185-
    Details
    In: Sustainability, MDPI AG, Vol. 9, No. 2 ( 2017-01-27), p. 185-
    Materialart: Online-Ressource
    ISSN: 2071-1050
    URL: Article
    DOI: 10.3390/su9020185
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2017
    ZDB Id: 2518383-7
    Standort Signatur Einschränkungen Verfügbarkeit
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    Online-Ressource
  • 9
    Online-Ressource
    Online-Ressource
    Photovoltaic Performances of Dye-Sensitized Solar Cells Based on Modified Polybutadiene Matrix Electrolytes by Sol-Gel Process
    MDPI AG ; 2022
    In:  Polymers Vol. 14, No. 12 ( 2022-06-09), p. 2347-
    Details
    In: Polymers, MDPI AG, Vol. 14, No. 12 ( 2022-06-09), p. 2347-
    Kurzfassung: A new type of polymer matrix electrolyte based on modified polybutadiene (modified PB) was developed for dye-sensitized solar cells (DSSCs) to improve their stability. The modified PB was fabricated by cross-linking the reaction of polybutadiene with siloxane groups as a substitute sol-gel process. A DSSC device using the modified PB matrix electrolyte showed an open-circuit voltage of 0.64 V, a short-circuit current density of 15.00 mA/cm2, and a fill factor of 0.58 under photointensity of 100 mW/cm2 at AM 1.5, consequently leading to an overall solar energy conversion efficiency of 5.49%. The DSSC device using the modified PB matrix electrolyte improved the conductivity, and the charge transfer ability showed the outstanding stability of the device.
    Materialart: Online-Ressource
    ISSN: 2073-4360
    URL: Article
    DOI: 10.3390/polym14122347
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2022
    ZDB Id: 2527146-5
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 10
    Online-Ressource
    Online-Ressource
    The Effects of Risk Perceptions Related to Particulate Matter on Outdoor Activity Satisfaction in South Korea
    MDPI AG ; 2020
    In:  International Journal of Environmental Research and Public Health Vol. 17, No. 5 ( 2020-03-02), p. 1613-
    Details
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 17, No. 5 ( 2020-03-02), p. 1613-
    Kurzfassung: In recent years, the Korean public has become aware of the form of air pollution known as particulate matter, with a consequent growth of public anxiety causing a negative risk perception about outdoor activity. This study aims at determining the causal relationship between risk perceptions about particulate matter and outdoor activity satisfaction in South Korea. An Internet survey was conducted with 412 people, and a structural equation model was used to perform confirmatory factor analysis. The statistically significant results show that the perceived risk of particulate matter is higher when people do not show interest in or trust public opinion or policy on the subject. This increases people’s perceptions of health risks, which in turn lowers their satisfaction with outdoor activity. Although trust levels in public opinion or policy had a positive impact on outdoor activity satisfaction, this was not statistically significant. These results are expected to contribute to risk communication guidelines in public opinion reporting and to the direction of environmental health policies in developing countries with high levels of air pollution, such as particulate matter.
    Materialart: Online-Ressource
    ISSN: 1660-4601
    URL: Article
    DOI: 10.3390/ijerph17051613
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2020
    ZDB Id: 2175195-X
    Standort Signatur Einschränkungen Verfügbarkeit
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