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  • MDPI AG  (14)
  • 1
    In: Antioxidants, MDPI AG, Vol. 10, No. 12 ( 2021-11-24), p. 1867-
    Abstract: Melatonin (MT) is a bio-antioxidant that has been widely used to prevent pregnancy complications, such as pre-eclampsia and IUGR during gestation. This experiment evaluated the impacts of dietary MT supplementation during pregnancy on reproductive performance, maternal–placental–fetal redox status, placental inflammatory response, and mitochondrial function, and sought a possible underlying mechanism in the placenta. Sixteen fifth parity sows were divided into two groups and fed each day of the gestation period either a control diet or a diet that was the same but for 36 mg of MT. The results showed that dietary supplementation with MT increased placental weight, while the percentage of piglets born with weight 〈 900 g decreased. Meanwhile, serum and placental MT levels, maternal–placental–fetal redox status, and placental inflammatory response were increased by MT. In addition, dietary MT markedly increased the mRNA levels of nutrient transporters and antioxidant-related genes involved in the Nrf2/ARE pathway in the placenta. Furthermore, dietary MT significantly increased ATP and NAD+ levels, relative mtDNA content, and the protein expression of Sirt1 in the placenta. These results suggested that MT supplementation during gestation could improve maternal–placental–fetal redox status and reproductive performance by ameliorating placental antioxidant status, inflammatory response, and mitochondrial dysfunction.
    Type of Medium: Online Resource
    ISSN: 2076-3921
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2704216-9
    SSG: 15,3
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  • 2
    Online Resource
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    MDPI AG ; 2022
    In:  Diagnostics Vol. 12, No. 10 ( 2022-10-21), p. 2560-
    In: Diagnostics, MDPI AG, Vol. 12, No. 10 ( 2022-10-21), p. 2560-
    Abstract: This study aimed to evaluate the value of the deep learning image reconstruction (DLIR) algorithm (GE Healthcare’s TrueFidelity™) in improving the image quality of low-dose computed tomography (LDCT) of the chest. First, we retrospectively extracted raw data of chest LDCT from 50 patients and reconstructed them by using model-based adaptive statistical iterative reconstruction-Veo at 50% (ASIR-V 50%) and DLIR at medium and high strengths (DLIR-M and DLIR-H). Three sets of images were obtained. Next, two radiographers measured the mean CT value/image signal and standard deviation (SD) in Hounsfield units at the region of interest (ROI) and calculated the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). Two radiologists subjectively evaluated the image quality using a 5-point Likert scale. The differences between the groups of data were analyzed through a repeated measures ANOVA or the Friedman test. Last, our result show that the three reconstructions did not differ significantly in signal (p 〉 0.05) but had significant differences in noise, SNR, and CNR (p 〈 0.001). The subjective scores significantly differed among the three reconstruction modalities in soft tissue (p 〈 0.001) but not in lung tissue (p 〉 0.05). DLIR-H had the best noise reduction ability and improved SNR and CNR without distorting the image texture, followed by DLIR-M and ASIR-V 50%. In summary, DLIR can provide a higher image quality at the same dose, enhancing the physicians’ diagnostic confidence and improving the diagnostic efficacy of LDCT for lung cancer screening.
    Type of Medium: Online Resource
    ISSN: 2075-4418
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662336-5
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  • 3
    In: Nanomaterials, MDPI AG, Vol. 12, No. 18 ( 2022-09-06), p. 3092-
    Abstract: Magnetoelectric (ME) coupling is highly desirable for sensors and memory devices. Herein, the polarization (P) and magnetization (M) of the DyFeO3 single crystal were measured in pulsed magnetic fields, in which the ME behavior is modulated by multi-magnetic order parameters and has high magnetic-field sensitivity. Below the ordering temperature of the Dy3+-sublattice, when the magnetic field is along the c-axis, the P (corresponding to a large critical field of 3 T) is generated due to the exchange striction mechanism. Interestingly, when the magnetic field is in the ab-plane, ME coupling with smaller critical fields of 0.8 T (a-axis) and 0.5 T (b-axis) is triggered. We assume that the high magnetic-field sensitivity results from the combination of the magnetic anisotropy of the Dy3+ spin and the exchange striction between the Fe3+ and Dy3+ spins. This work may help to search for single-phase multiferroic materials with high magnetic-field sensitivity.
    Type of Medium: Online Resource
    ISSN: 2079-4991
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662255-5
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  • 4
    In: Energies, MDPI AG, Vol. 16, No. 5 ( 2023-03-04), p. 2464-
    Abstract: Nitrogen adsorption experiments have been extensively applied to shale pore structure research and evaluation. The pore structure can be quantitatively characterized in accordance with the nitrogen adsorption–desorption isotherm using various calculation models, whereas the results obtained using different models can more effectively indicate the pore characteristics of shale remains unclear. Further, there has not been any unified process in the optimization of calculation models for pore size distribution (PSD). In this study, the Barret–Joyner–Halenda adsorption (BJH-AD) and BJH desorption (BJH-DE) models were used with Longmaxi Formation shale as an example. Subsequently, the density functional theory (DFT) calculations were conducted on different shale lithofacies samples. Next, the pore structure parameters and heterogeneity obtained using different models were compared, and the consistency parameters of different models were obtained in accordance with Cronbach’s alpha. The results indicated that the pore structure parameters obtained using the BJH-AD model were underestimated since the macroscopic thermodynamic theory was not applicable to this study. The DFT model showed multiple peaks in the range of 1–10 nm, whereas the BJH-DE model had a significant artificial peak in the range of 3.8 nm due to the tensile strength effect, thus suggesting that the DFT model is more capable of characterizing the pores with a pore size 10 nm lower than the BJH model. The PSD curves generated using the three models exhibited multifractal characteristics, whereas the results of the heterogeneity achieved using different models were different. Moreover, the consistency of the results of different models can be studied in depth by combining Cronbach’s alpha with various heterogeneity parameters. The DFT model exhibited high consistency in pore structure parameters and pore heterogeneity, thus suggesting that the DFT method of N2 is the optimal physical adsorption data analysis method in the shale mesoporous range. Accordingly, the nitrogen adsorption curve, the hysteresis loop shape, multifractal parameters, and Cronbach’s alpha were integrated to generate a working flow chart of the nitrogen adsorption model for N2-adsorption-model optimization.
    Type of Medium: Online Resource
    ISSN: 1996-1073
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2437446-5
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  • 5
    In: Materials, MDPI AG, Vol. 16, No. 17 ( 2023-08-23), p. 5759-
    Abstract: Surrounding rock deformation and consequent support failure are the most prominent issues in red-bed rock tunnel engineering and are mainly caused by the effects of unloading, rheology, and swelling. This study investigated the mechanical responses of two kinds of red-bed mudstone and sandstone under unloading conditions via laboratory observation. Volume dilation was observed on the rocks during unloading, and the dilatancy stress was linear with the initial confining pressure. However, the ratios of dilatancy stress to peak stress of the two rocks kept at a range from 0.8 to 0.9, regardless of confining pressures. Both the elastic strain energy and the dissipated energy evolved synchronously with the stress–strain curve and exhibited conspicuous confining pressure dependence. Special attention was paid to the evolution behavior of the dilatancy angle. The dilatancy angle changed linearly during unloading. When the confining pressure was 10 MPa, the dilatancy angle of mudstone decreased from 26.8° to 12.5° whereas the dilatancy angle of sandstone increased from 34.6° to 51.1°; when the confining pressure rose to 25 MPa, the dilatancy angle of mudstone and sandstone decreased from 45.8° to 17.4° and increased from 21.7° to 39.5°, respectively. To further understand the evolution of the dilatancy angle, we discussed the links between the variable dilatancy angle and the processes of rock deformation and energy dissipation.
    Type of Medium: Online Resource
    ISSN: 1996-1944
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2487261-1
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  • 6
    In: Minerals, MDPI AG, Vol. 9, No. 3 ( 2019-03-26), p. 198-
    Abstract: Pore connectivity of lacustrine shales was inadequately documented in previous papers. In this work, lacustrine shales from the lower Cretaceous Shahezi Formation in the Changling Fault Depression (CFD) were investigated using field emission scanning electron microscopy (FE-SEM), mercury intrusion capillary pressure (MICP), low pressure gas (CO2 and N2) sorption (LPGA) and spontaneous fluid imbibition (SFI) experiments. The results show that pores observed from FE-SEM images are primarily interparticle (interP) pores in clay minerals and organic matter (OM) pores. The dominant pore width obtained from LPGA and MICP data is in the range of 0.3–0.7 nm and 3–20 nm. The slopes of n-decane and deionized (DI) water SFI are in the range of 0.34–0.55 and 0.22–0.38, respectively, suggesting a mixed wetting nature and better-connected hydrophobic pores than hydrophilic pores in the Shahezi shales. Low pore connectivity is identified by the dominant nano-size pore widths (0.3–20 nm), low DI water SFI slopes (around 0.25), high geometric tortuosity (4.75–8.89) and effective tortuosity (1212–6122). Pore connectivity follows the order of calcareous shale 〉 argillaceous shale 〉 siliceous shale. The connected pores of Shahezi shales is mainly affected by the high abundance and coexistence of OM pores and clay, carbonate minerals host pores.
    Type of Medium: Online Resource
    ISSN: 2075-163X
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2655947-X
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  • 7
    In: Nanomaterials, MDPI AG, Vol. 12, No. 14 ( 2022-07-21), p. 2510-
    Abstract: Superhydrophobic materials have been widely applied in rapid removal and collection of oils from oil/water mixtures for increasing damage to environment and human beings caused by oil-contaminated wastewater and oil spills. Herein, superhydrophobic materials were fabricated by a novel polypyrrole (PPy)/ZnO coating followed by hexadecyltrimethoxysilane (HDTMS) modification for versatile oil/water separation with high environmental and excellent reusability. The prepared superhydrophobic surfaces exhibited water contact angle (WCA) greater than 150° and SA less than 5°. The superhydrophobic fabric could be applied for separation of heavy oil or light oil/water mixtures and emulsions with the separation efficiencies above 98%. The coated fabric also realized highly efficient separation with harsh environmental solutions, such as acid, alkali, salt, and hot water. The superhydrophobic fabric still remained, even after 80 cycles of separation and 12 months of storage in air, proving excellent durability. These novel superhydrophobic materials have indicated great development potentials for oil/water separation in practical applications.
    Type of Medium: Online Resource
    ISSN: 2079-4991
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662255-5
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  • 8
    In: Energies, MDPI AG, Vol. 12, No. 7 ( 2019-03-28), p. 1207-
    Abstract: Organic matter (OM) pores are significant for shale gas accumulation and flow mechanisms. The pores of Wufeng-Longmaxi (W-L) shale in the Sichuan Basin, China have been extensively characterized, however, the proportion of OM pores in this shale have not been adequately discussed. In this study, the contribution of OM pores to the total pore volume of W-L shale was quantitatively studied through the analysis of OM isolation, field emission scanning electron microscopy (FE-SEM) and low-pressure CO2 and N2 adsorption (LPGA). FE-SEM images showed abundant OM pores, interparticle pores and intraparticle pores with various shapes and widths in the W-L shales. The pore size distribution (PSD) of the isolated OM from five shale samples showed a consistent, unimodal pattern. The pore volume of isolated OM was greater than that of the bulk shale samples, suggesting that OM is more porous than the inorganic compositions in shales. The average contribution of OM to the volumes of micropores, mesopores and macropores was 58.42%, 10.34% and 10.72%, respectively. Therefore, the pore volume of the W-L shale was dominantly related to inorganic minerals. This was probably due to the small weight ratio of OM in the shale samples (1.5 wt%–4.2 wt%). The findings of this study reveal the different effects of OM and minerals on pore development, and provide new insights into the quantitative contribution of OM pores to the total pore volume of the W-L shale.
    Type of Medium: Online Resource
    ISSN: 1996-1073
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2437446-5
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  • 9
    In: Electronics, MDPI AG, Vol. 11, No. 19 ( 2022-09-28), p. 3097-
    Abstract: The autonomous technology of unmanned platforms is the most dynamic frontier among fields of technology and, inevitably, is trending towards future development. Aiming at the dual requirements of reliable and real-time autonomous decision-making of unmanned underwater vehicles in complex and unfamiliar environments, this article proposes an intelligent decision-making method of attack behavior based on model fusion. The experimental dataset is generated through simulation modeling, and an appropriate amount of noise is added to simulate the observation error in a real situation. The threshold of weapon-hit probability is set according to the requirements of combat missions, and the decision-making of attack behavior is transformed into the problem of imbalanced sample classification with noisy data. Through theoretical analysis and experimental testing, the classification effects of algorithms such as Logistic Regression (LR), K-nearest neighbor (KNN), support vector machine (SVM), multilayer perceptron (MLP), decision tree (DT), and ensemble learning are compared. On this basis, the intelligent decision model is constructed by using synthetic minority oversampling technique resampling and three model fusion methods of voting, stacking, and blending. The experimental results show that compared with traditional simulation decision-making and common classification algorithms, the proposed method has higher accuracy, recall rate, area-under-the-curve value, and model generalization ability. It can not only effectively identify the impact of noise data on attack-behavior decision-making, but also ensures the decision-making speed through offline training, and provides references for the research in the field of equipment development and intelligent decision-making in the future.
    Type of Medium: Online Resource
    ISSN: 2079-9292
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662127-7
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  • 10
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 19, No. 16 ( 2022-08-11), p. 9921-
    Abstract: This study investigated the interactions between self-perceived weight status and lifestyle behaviors, and their associations with childhood obesity among school children. Methods: Cross-sectional study data from a nationwide sample of 3258 participants (aged 8–15 years old) during 2015–2017 were used. Self-perceived weight status and lifestyle factors (dietary intake and physical activity) were assessed using self-administered questionnaires. Multivariable mixed-effects models tested the effect of interactions between weight self-perception and behavioral factors on overweight and obesity (ow/ob). Results: Overall ow/ob prevalence based on BMI was 30.9% (38.5% for boys, 23.0% for girls). Based on self-perceived weight status, ow/ob prevalence was 37.7% (35.8% for boys, 39.7% for girls). 41.2% of boys and 25.9% of girls underestimated their actual weight status. The interaction between self-perceived weight status and meat consumption was associated with ow/ob in boys, while the interaction between self-assessed weight status and protein foods and sedentary lifestyle were associated with ow/ob in girls. The attributable proportions of these three factors were 39.8%, 48.2%, and 34.6%, respectively. Conclusions: The self-perceived weight status was different from their actual weight status in children. The interactions between self-perceived weight status and lifestyle behaviors were associated with ow/ob. Health promotion programs that empower children to have appropriate self-awareness of weight status, eating, and physical activity behaviors need to be developed and implemented.
    Type of Medium: Online Resource
    ISSN: 1660-4601
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2175195-X
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