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  • MDPI AG  (14)
  • 1
    Online Resource
    Online Resource
    Species Diversity of Phaeobotryon Associated with Tree Canker and Dieback Diseases in Xinjiang, China
    MDPI AG ; 2023
    In:  Forests Vol. 14, No. 5 ( 2023-04-23), p. 864-
    Details
    In: Forests, MDPI AG, Vol. 14, No. 5 ( 2023-04-23), p. 864-
    Abstract: Withered branch disease is a major threat to the health of forest trees, resulting in the death of susceptible branches and even the whole plant. Botryosphaeriaceae members (e.g., Phaeobotryon spp.) are common pathogenic fungi that cause withered branches, canker and dieback disease symptoms in woody plants. This study aimed to identify the Phaeobotryon species inhabiting tree species with canker and dieback symptoms in Xinjiang Uyghur Autonomous Region, China, based on both morphological and phylogenetic approaches. In the current study, branches and twigs showing typical symptoms of canker and dieback were collected from Elaeagnus angustifolia, Juglans regia, Malus pumila, Malus ‘Royalty’, Prunus armeniaca (wild apricot) and Rhus typhina growing on Tianshan Mountain in the Xinjiang Uygur Autonomous Region of China. Phaeobotryon species isolated from these samples were characterized based on methods of morphology and molecular phylogeny. As a result, two species were identified: P. rhoinum and a new species Phaeobotryon mali sp. nov. Here, we provide a description and illustrations of this new species for science.
    Type of Medium: Online Resource
    ISSN: 1999-4907
    URL: Article
    DOI: 10.3390/f14050864
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2527081-3
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  • 2
    Online Resource
    Online Resource
    The Role of Circular RNAs in the Physiology and Pathology of the Mammalian Ovary
    MDPI AG ; 2022
    In:  International Journal of Molecular Sciences Vol. 23, No. 23 ( 2022-12-02), p. 15204-
    Details
    In: International Journal of Molecular Sciences, MDPI AG, Vol. 23, No. 23 ( 2022-12-02), p. 15204-
    Abstract: Circular RNAs (circRNAs) are an abundant class of endogenous non-coding RNAs (ncRNAs) generated from exonic, intronic, or untranslated regions of protein-coding genes or intergenic regions. The diverse, stable, and specific expression patterns of circRNAs and their possible functions through cis/trans regulation and protein-coding mechanisms make circRNA a research hotspot in various biological and pathological processes. It also shows practical value as biomarkers, diagnostic indicators, and therapeutic targets. This review summarized the characteristics, classification, biogenesis and elimination, detection and confirmation, and functions of circRNAs. We focused on research advances circRNAs in the mammalian ovary under conditions including ovarian cancer, polycystic ovarian syndrome (PCOS), and maternal aging, as well as during reproductive status, including ovarian follicle development and atresia. The roles of circRNAs in high reproductive traits in domestic animals were also summarized. Finally, we outlined some obstructive factors and prospects to work with circRNA, aiming to provide insights into the functional research interests of circRNAs in the reproduction and gynecology areas.
    Type of Medium: Online Resource
    ISSN: 1422-0067
    URL: Article
    DOI: 10.3390/ijms232315204
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2019364-6
    SSG: 12
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  • 3
    Online Resource
    Online Resource
    Research Progress on Triboelectric Nanogenerator for Sports Applications
    MDPI AG ; 2022
    In:  Energies Vol. 15, No. 16 ( 2022-08-10), p. 5807-
    Details
    In: Energies, MDPI AG, Vol. 15, No. 16 ( 2022-08-10), p. 5807-
    Abstract: Progress in science and technology drives the continuous innovation of energy collection and utilization. In the field of sports, the information collection and analysis based on Internet of things have attracted particular attention. Moreover, triboelectric nanogenerator (TENG) has promising applications in the field of sports. Here, we introduce the working principle of the TENG then the progress of the TENG as a wearable energy sensor is examined in the two fields of basic human activities and sports, especially competitive sports. On this basis, it is considered that the stability of devices, the universality of materials, and the scientificity of application of the TENG in the future need to be improved. We provide a direction for further upgrading energy collection technology to promote the high-quality development of human mechanical energy sensing in the field of sports.
    Type of Medium: Online Resource
    ISSN: 1996-1073
    URL: Article
    DOI: 10.3390/en15165807
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2437446-5
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  • 4
    Online Resource
    Online Resource
    A Flexible Lightweight Triboelectric Nanogenerator for Protector and Scoring System in Taekwondo Competition Monitoring
    MDPI AG ; 2022
    In:  Electronics Vol. 11, No. 9 ( 2022-04-20), p. 1306-
    Details
    In: Electronics, MDPI AG, Vol. 11, No. 9 ( 2022-04-20), p. 1306-
    Abstract: Nowadays, the applications of the triboelectric nanogenerator in sensing and monitoring sports experience a blooming prosperity. Here, we report a flexible and lightweight triboelectric nanogenerator (FL-TENG) made of hydrogel electrodes, polytetrafluoroethylene (PTFE), PDMS, and polyurethane (PU). Based on the triboelectric effect, the FL-TENG can work as a self-powered sensor attaching to taekwondo protective gear, which can be used to monitor athletes’ competition performance and improve the fairness of the competition. In addition, the FL-TENG can drive micro-wireless devices for wireless transmitting sports data during the competition in real time. This kind of sustainable green self-powered sensor provides a new path for the field of sports competition monitoring.
    Type of Medium: Online Resource
    ISSN: 2079-9292
    URL: Article
    DOI: 10.3390/electronics11091306
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662127-7
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  • 5
    Online Resource
    Online Resource
    LEF1 Enhances the Progression of Colonic Adenocarcinoma via Remodeling the Cell Motility Associated Structures
    MDPI AG ; 2021
    In:  International Journal of Molecular Sciences Vol. 22, No. 19 ( 2021-10-08), p. 10870-
    Details
    In: International Journal of Molecular Sciences, MDPI AG, Vol. 22, No. 19 ( 2021-10-08), p. 10870-
    Abstract: Lymphoid enhancer-binding factor 1 (LEF1) is a key transcription factor mediating the Wnt signaling pathway. LEF1 is a regulator that is closely associated with tumor malignancy and is usually upregulated in cancers, including colonic adenocarcinoma. The underlying molecular mechanisms of LEF1 regulation for colonic adenocarcinoma progression remain unknown. To explore it, the LEF1 expression in caco2 cells was inhibited using an shRNA approach. The results showed that downregulation of LEF1 inhibited the malignancy and motility associated microstructures, such as polymerization of F-actin, β-tubulin, and Lamin B1 in caco2 cells. LEF1 inhibition suppressed the expression of epithelial/endothelial-mesenchymal transition (EMT) relevant genes. Overall, the current results demonstrated that LEF1 plays a pivotal role in maintaining the malignancy of colonic adenocarcinoma by remodeling motility correlated microstructures and suppressing the expression of EMT-relevant genes. Our study provided evidence of the roles LEF1 played in colonic adenocarcinoma progression, and suggest LEF1 as a potential target for colonic adenocarcinoma therapy.
    Type of Medium: Online Resource
    ISSN: 1422-0067
    URL: Article
    DOI: 10.3390/ijms221910870
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2019364-6
    SSG: 12
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  • 6
    Online Resource
    Online Resource
    Different Structures of Arabinoxylan Hydrolysates Alleviated Caco-2 Cell Barrier Damage by Regulating the TLRs/MyD88/NF-κB Pathway
    MDPI AG ; 2022
    In:  Foods Vol. 11, No. 21 ( 2022-11-07), p. 3535-
    Details
    In: Foods, MDPI AG, Vol. 11, No. 21 ( 2022-11-07), p. 3535-
    Abstract: Arabinoxylan (AX) has been associated with alleviating intestinal barrier damage, and different structures of AX give rise to different effects on the intestinal barrier. This study investigated the main structural characteristics of AX, whose functional properties are attributed to alleviating intestinal barrier damage, and clarified their underlying mechanisms. An in vitro Caco-2 cell model was established to investigate the intestinal barrier effects of AX with various degrees of substitution (Ds) and molecular weight (Mw), with an added MyD88 inhibitor to verify the signaling pathways. Arabinoxylan treated with endo-1,4-β-xylanase (AXX) with higher Ds and Mw showed stronger physiological activity, which might be correlated with the uronic acid and bound ferulic acid contents in AXX. Moreover, AXX alleviated the intestinal barrier damage by upregulating the transepithelial electrical resistance (TER) and alleviating the decrease of claudin-1 (p 〈 0.05). AXX regulated the expression of inflammatory factors IL-2, TNF-α, IL-6 and IL-10 (p 〈 0.05). In addition, AXX reduced the intestinal barrier damage induced via inhibiting the TLRs/MyD88/NF-κB pathway and activating the TLRs/PKC pathway. Thus, AX with higher Ds and Mw might be better in alleviating intestinal barrier damage, and MyD88 might be the key point of AXX to identify these signaling pathways.
    Type of Medium: Online Resource
    ISSN: 2304-8158
    URL: Article
    DOI: 10.3390/foods11213535
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2704223-6
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  • 7
    Online Resource
    Online Resource
    Spatial Layout of Cotton Seed Production Based on Hierarchical Classification: A Case Study in Xinjiang, China
    MDPI AG ; 2021
    In:  Agriculture Vol. 11, No. 8 ( 2021-08-10), p. 759-
    Details
    In: Agriculture, MDPI AG, Vol. 11, No. 8 ( 2021-08-10), p. 759-
    Abstract: Cotton seed production is the main form of agriculture in Xinjiang, China. Unreasonable distribution of cotton seed production results in a waste of water, land, and human resources. In this study, we established a hierarchical classification integrating method; investigated the spatial suitability of climate, land and water resources, and infrastructure; examined the production risk and planting history; and integrated spatial suitability and production risk and history to produce the spatial layout of seed production for early-maturing cotton (EMC), early–medium-maturing cotton (EMMC), and long staple cotton (LSC) in Xinjiang. The results indicated that the appropriate areas for EMC, EMMC, and LSC seed production are 6.4 × 105, 5.5 × 105, and 3.6 × 105 ha, respectively. By combining the suitable areas of seed production for the three cotton species, we concluded that the superior and most suitable area for producing cotton seed of EMC, EMMC, or LSC is located in the western Tarim Basin. The sub-suitable area for cotton seed production of EMC, EMMC, or LSC is mostly distributed in the western and northern Tarim Basin. This research provides a good solution to the selection of cotton seed production base; however, adoption will depend on the actual preference and market factors.
    Type of Medium: Online Resource
    ISSN: 2077-0472
    URL: Article
    DOI: 10.3390/agriculture11080759
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2651678-0
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  • 8
    Online Resource
    Online Resource
    Significance of Resveratrol in Clinical Management of Chronic Diseases
    MDPI AG ; 2017
    In:  Molecules Vol. 22, No. 8 ( 2017-08-18), p. 1329-
    Details
    In: Molecules, MDPI AG, Vol. 22, No. 8 ( 2017-08-18), p. 1329-
    Type of Medium: Online Resource
    ISSN: 1420-3049
    URL: Article
    DOI: 10.3390/molecules22081329
    Language: English
    Publisher: MDPI AG
    Publication Date: 2017
    detail.hit.zdb_id: 2008644-1
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  • 9
    Online Resource
    Online Resource
    Analysis of Carbon Tetrachloride-Extractable Species from Daxing Bituminous Coal
    MDPI AG ; 2020
    In:  Applied Sciences Vol. 10, No. 2 ( 2020-01-09), p. 494-
    Details
    In: Applied Sciences, MDPI AG, Vol. 10, No. 2 ( 2020-01-09), p. 494-
    Abstract: Soxhlet extraction (SE), ultrasonic-assisted extraction (UAE), and microwave-assisted extraction (MAE) were carried out on Daxing coal with carbon tetrachloride. The extracted components were analyzed by GC-MS while the residues of the coal after extractions were analyzed by FT-IR spectroscopy. The obtained IR spectra indicated that the functional groups were barely changed in strength for the coal before and after extractions concluding that the macromolecular structures of coal were not destroyed in the extraction processes. XRD diagrams showed the peak around θ = 47 was totally disappeared by all the three extractions, indicating that the graphite-like structural substances in the coal were totally destroyed in the extraction processes. GC/MS analysis showed that: (1) The SE method extracted the least number of substances from the coal; on the other hand, the extracted compounds are largely chlorinated which can be explained by the free radical mechanism. (2) MAE extracted 75 organic compounds of which 53 are oxygen-containing substances. A small portion of non-alkanes (1.19%) was found, which is in contrast to the other two extraction methods. Moreover, a few biomarker compounds were also identified including hexaoxane, 2-methylcholest-3-ene, 6,9,12-tripropylheptadecane, and 17α-21β-28,30-bisnorhopane. (3) The three extraction methods gave totally different extraction patterns for the same coal, highlighting that the extraction method can dominate the outcome of the extracted products. The mechanisms behind these extraction processes are discussed. This study provides a base for the future choice of the extraction methods in terms of outcomes of the extraction products.
    Type of Medium: Online Resource
    ISSN: 2076-3417
    URL: Article
    DOI: 10.3390/app10020494
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2704225-X
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  • 10
    Online Resource
    Online Resource
    Seasonal Spatiotemporal Changes in the NDVI and Its Driving Forces in Wuliangsu Lake Basin, Northern China from 1990 to 2020
    MDPI AG ; 2023
    In:  Remote Sensing Vol. 15, No. 12 ( 2023-06-07), p. 2965-
    Details
    In: Remote Sensing, MDPI AG, Vol. 15, No. 12 ( 2023-06-07), p. 2965-
    Abstract: In the context of global climate change, many studies have focused on the interannual vegetation variation trends and their response to precipitation and temperature, but ignored the effects of seasonal variability. This study explored the relationship between normalized difference vegetation index (NDVI) and seasonal climate elements in the Wuliangsu Lake Basin area from 1990 to 2020, and quantified the impacts of human activities on vegetation dynamics. We used Landsat series data to analyze the spatial and temporal variation of the NDVI using the trend analysis method, the Theil–Sen median, the Mann–Kendall test, and the Hurst index. Then, we used meteorological data and land use data to quantify the effects of human activities using residual analysis, and correlation methods to determine the driving forces of NDVI variations. The results showed that the NDVI changes presented obvious regional characteristics, with a decreasing trend from southeast to northwest in Wuliangsu Lake Basin. Due to global warming, the start of the growing season (SOS) is 4.3 days (2001 to 2010) and 6.8 days (2011 to 2020) earlier compared with 1990 to 2000. The end of the season (EOS) is advanced by 3.6 days (2001 to 2010), and delayed by 8.9 days (2011 to 2020). Seasonal (spring, summer, autumn, and winter) NDVIs with precipitation and temperature show spatial heterogeneity. Further, changes in grasslands and woodlands were vulnerable to climate change and human activities. Since the beginning of the 21st century, human activity was the driving force for vegetation improvement in the Dengkou, west-central, north and southwest regions, where ecological instability is weak. This finding can provide a theoretical basis for the implementation of the same type of ecological restoration projects and the construction of ecological civilization, and contribute to the regional green and sustainable development.
    Type of Medium: Online Resource
    ISSN: 2072-4292
    URL: Article
    DOI: 10.3390/rs15122965
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2513863-7
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