GLORIA

GEOMAR Library Ocean Research Information Access

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    MDPI AG ; 2023
    In:  International Journal of Molecular Sciences Vol. 24, No. 9 ( 2023-04-27), p. 7952-
    In: International Journal of Molecular Sciences, MDPI AG, Vol. 24, No. 9 ( 2023-04-27), p. 7952-
    Abstract: Visual disabilities affect more than 250 million people, with 43 million suffering from irreversible blindness. The eyes are an extension of the central nervous system which cannot regenerate. Neural tissue engineering is a potential method to cure the disease. Injectability is a desirable property for tissue engineering scaffolds which can eliminate some surgical procedures and reduce possible complications and health risks. We report the development of the anisotropic structured hydrogel scaffold created by a co-injection of cellulose nanofiber (CNF) solution and co-polypeptide solution. The positively charged poly (L-lysine)-r-poly(L-glutamic acid) with 20 mol% of glutamic acid (PLLGA) is crosslinked with negatively charged CNF while promoting cellular activity from the acid nerve stimulate. We found that CNF easily aligns under shear forces from injection and is able to form hydrogel with an ordered structure. Hydrogel is mechanically strong and able to support, guide, and stimulate neurite growth. The anisotropy of our hydrogel was quantitatively determined in situ by 2D optical microscopy and 3D X-ray tomography. The effects of PLLGA:CNF blend ratios on cell viability, neurite growth, and neuronal signaling are systematically investigated in this study. We determined the optimal blend composition for stimulating directional neurite growth yielded a 16% increase in length compared with control, reaching anisotropy of 30.30% at 10°/57.58% at 30°. Using measurements of calcium signaling in vitro, we found a 2.45-fold increase vs. control. Based on our results, we conclude this novel material and unique injection method has a high potential for application in neural tissue engineering.
    Type of Medium: Online Resource
    ISSN: 1422-0067
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2019364-6
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    Online Resource
    Online Resource
    MDPI AG ; 2019
    In:  Energies Vol. 12, No. 10 ( 2019-05-17), p. 1887-
    In: Energies, MDPI AG, Vol. 12, No. 10 ( 2019-05-17), p. 1887-
    Abstract: This paper proposes a control strategy for the energy saving of refrigerating chambers. Combining binary coding and proteome reorganization, the binary proteome algorithm (BPA) is proposed to solve this problem. The refrigeration system model is firstly established based on the performance data of compressors and temperature measurements of each refrigerating chamber. The objective function is an averaged coefficient of performance (COP), which considers the switching loss of the compressors, power consumption of the compressors, and refrigerating capacity of the chambers. The control strategy is defined as an optimization problem with constraints to avoid the ineffective operation of a refrigeration system for improving the COP. BPA is adopted to solve the control strategy for optimizing energy saving. The effectiveness and efficiency of the BPA are demonstrated using a real system, and the results are compared with the original control strategy. Results show that the average power consumption drops from 115.92 kW to 108.82 kW, and the average COP value rises from 1.92 to 2.03. The proposed control strategy is feasible, robust, and more effective in energy-saving problems. Other than energy saving, the proposed control strategy also has the benefits of reducing the evaporator frost formation, which allows the products to avoid chill damage.
    Type of Medium: Online Resource
    ISSN: 1996-1073
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2437446-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 3
    Online Resource
    Online Resource
    MDPI AG ; 2022
    In:  Energies Vol. 15, No. 11 ( 2022-05-28), p. 3981-
    In: Energies, MDPI AG, Vol. 15, No. 11 ( 2022-05-28), p. 3981-
    Abstract: This paper proposes a fault diagnosing system for the Ice-Storage Air-Conditioning System (ISACS) to supervise the operation conditions of the brine chillers. Combining the Radial Basis Function Network (RBFN) and Robust Quality Design (RQD), an Enhanced RBFN (ERBFN) is proposed to pursue fast and accurate fault diagnosis. The RQD method is used to adjust the parameters in the RBFN training stage to improve the searching ability, and good performance with a close spike tracking capability can be seen. The efficiency of the brine chiller in the ISACS was considered as the quality characteristics, the values measured by all instruments were considered as control factors, and noise factors were abnormal variable control factors in the system. ERBFN can improve the efficiency of the ISACS and prevent the equipment from being damaged without warning. ERBFN is used for fault diagnosis to ensure the ISACS performance is normal. Experimental results are provided to show the effectiveness of the proposed method. The new artificial neural network algorithm proposed in this paper was successfully applied to the fault diagnosis of ISACS. It not only provides a reference for enterprises but can also be applied to studies on other topics in the future.
    Type of Medium: Online Resource
    ISSN: 1996-1073
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2437446-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...