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  • 1
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    Effect of the Symbiosis with Mycoplasma hominis and Candidatus Mycoplasma Girerdii on Trichomonas vaginalis Metronidazole Susceptibility
    MDPI AG ; 2022
    In:  Antibiotics Vol. 11, No. 6 ( 2022-06-16), p. 812-
    Details
    In: Antibiotics, MDPI AG, Vol. 11, No. 6 ( 2022-06-16), p. 812-
    Kurzfassung: Trichomoniasis, the most common non-viral sexually transmitted infection worldwide, is caused by the protozoon Trichomonas vaginalis. The 5- nitroimidazole drugs, of which metronidazole is the most prescribed, are the only effective drugs to treat trichomoniasis. Resistance against metronidazole is increasingly reported among T. vaginalis isolates. T. vaginalis can establish an endosymbiosis with two Mycoplasma species, Mycoplasma hominis and Candidatus Mycoplasma girerdii, whose presence has been demonstrated to influence several aspects of the protozoan pathobiology. The role of M. hominis in T. vaginalis resistance to metronidazole is controversial, while the influence of Ca. M. girerdii has never been investigated. In this work, we investigate the possible correlation between the presence of Ca. M. girerdii and/or M. hominis and the in vitro drug susceptibility in a large group of T. vaginalis isolated in Italy and in Vietnam. We also evaluated, via RNA-seq analysis, the expression of protozoan genes involved in metronidazole resistance in a set of syngenic T. vaginalis strains, differing only for the presence/absence of the two Mycoplasmas. Our results show that the presence of M. hominis significantly increases the sensitivity to metronidazole in T. vaginalis and affects gene expression. On the contrary, the symbiosis with Candidatus Mycoplasma girerdii seems to have no effect on metronidazole resistance in T. vaginalis.
    Materialart: Online-Ressource
    ISSN: 2079-6382
    URL: Article
    DOI: 10.3390/antibiotics11060812
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2022
    ZDB Id: 2681345-2
    SSG: 15,3
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  • 2
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    Molecular Identification and Appraisal of the Genetic Variation of Taenia saginata in Central Regions of Vietnam
    MDPI AG ; 2022
    In:  Life Vol. 12, No. 1 ( 2022-01-04), p. 70-
    Details
    In: Life, MDPI AG, Vol. 12, No. 1 ( 2022-01-04), p. 70-
    Kurzfassung: Taenia saginata is a globally distributed tapeworm responsible for human taeniasis due to the ingestion of raw or undercooked beef. T. saginata is present in several Asian countries, including China, Thailand, Lao PDR, Cambodia, and Vietnam, but little is known about its genetic variation. Studying the tapeworm’s phylogeographic patterns is crucial to better understanding their association with the geographic distribution of taeniasis/cysticercosis in human populations. In the present study, 38 specimens of this putative species were collected in central regions of Vietnam and analysed using the mitochondrial gene Cytochrome c Oxidase subunit I (COI) as a molecular marker to assess the correct species identification and investigate the level of genetic variation at different geographic scales. Phylogenetic and phylogeographic analyses were carried out on a dataset that included COI sequences from Vietnamese specimens and from all conspecifics available in GenBank to date. The results showed that the collected Vietnamese specimens belonged to the species T. saginata. In Southeast Asia, signs of a possible founder effect were discovered, with the most common haplotypes frequent and present in many countries, except Lao PDR, which shares its most common haplotype only with individuals from Thailand. Remarkably, a unique taxonomic entity was found worldwide, even though the available COI sequences of T. saginata belonging to non-Asiatic countries are, at present, limited. Therefore, future studies including more COI sequences from a higher number of countries and the use of a combined molecular approach with multiple genetic markers would be useful to provide deeper insight into the global genetic variation of this species.
    Materialart: Online-Ressource
    ISSN: 2075-1729
    URL: Article
    DOI: 10.3390/life12010070
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2022
    ZDB Id: 2662250-6
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  • 3
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    Molecular Identification and Characterization of Probiotic Bacillus Species with the Ability to Control Vibrio spp. in Wild Fish Intestines and Sponges from the Vietnam Sea
    MDPI AG ; 2021
    In:  Microorganisms Vol. 9, No. 9 ( 2021-09-10), p. 1927-
    Details
    In: Microorganisms, MDPI AG, Vol. 9, No. 9 ( 2021-09-10), p. 1927-
    Kurzfassung: Vibriosis in farmed animals is a serious threat to aquaculture worldwide. Using probiotics and anti-Vibrio antimicrobial substances in aquaculture systems can be a means of preventing Vibrio infections. Therefore, we aimed to characterize and compare 16 potential anti-Vibrio probiotics (Vi+) isolated from marine sponges and fish intestines collected from the Vietnam Sea, as well as an anti-Vibrio bacteriocin to fully explore their application potentials. 16S rRNA sequencing confirmed all Vi+ to be Bacillus species with different strain variants across two sample types. An obvious antimicrobial spectrum toward Gram-negative bacteria was observed from intestinal Vi+ compared to sponge-associated Vi+. The reason was the higher gene frequency of two antimicrobial compounds, non-ribosomal peptides (NRPS) and polyketide type-I (PKS-I) from intestinal Vi+ (66.7%) than sponge-associated Vi+ (14.3% and 0%, respectively). Additionally, a three-step procedure was performed to purify an anti-Vibrio bacteriocin produced by B. methylotrophicus NTBD1, including (i) solvent extraction of bacteriocin from cells, (ii) hydrophobic interaction chromatography, and (iii) reverse-phase HPLC. The bacteriocin had a molecular weight of ~2–5 kDa, was sensitive to proteolysis and thermally stable, and showed a broad antimicrobial spectrum, all of which are essential properties for promising feed additives. This study provides necessary information of the potential of probiotic Bacillus species with anti-Vibrio antimicrobial properties to study their further use in sustainable aquaculture.
    Materialart: Online-Ressource
    ISSN: 2076-2607
    URL: Article
    DOI: 10.3390/microorganisms9091927
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2021
    ZDB Id: 2720891-6
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  • 4
    Online-Ressource
    Online-Ressource
    Consumer Preference and Attitude Regarding Online Food Products in Hanoi, Vietnam
    MDPI AG ; 2018
    In:  International Journal of Environmental Research and Public Health Vol. 15, No. 5 ( 2018-05-14), p. 981-
    Details
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 15, No. 5 ( 2018-05-14), p. 981-
    Materialart: Online-Ressource
    ISSN: 1660-4601
    URL: Article
    DOI: 10.3390/ijerph15050981
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2018
    ZDB Id: 2175195-X
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  • 5
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    TiO2 Nanowires on TiO2 Nanotubes Arrays (TNWs/TNAs) Decorated with Au Nanoparticles and Au Nanorods for Efficient Photoelectrochemical Water Splitting and Photocatalytic Degradation of Methylene Blue
    MDPI AG ; 2022
    In:  Coatings Vol. 12, No. 12 ( 2022-12-13), p. 1957-
    Details
    In: Coatings, MDPI AG, Vol. 12, No. 12 ( 2022-12-13), p. 1957-
    Kurzfassung: In this study, TiO2 nanowires on TiO2 nanotubes arrays (TNWs/TNAs) and Au-decorated TNWs/TNAs nanostructures are designed and fabricated as a new type of photoanode for photoelectrochemical (PEC) water splitting. The TNWs/TNAs were fabricated on Ti folds by anodization using an aqueous NH4F/ethylene glycol solution, while Au nanoparticles (NPs) and Au nanorods (NRs) were synthesized by Turkevich methods. We studied the crystal structure, morphology, and PEC activity of four types of nanomaterial photoanodes, including TNWs/TNAs, Au NPs- TNWs/TNAs, Au NRs-TNWs/TNAs, and Au NPs-NRs-TNWs/TNAs. The TiO2 and Au-TiO2 samples exhibited pure anatase phase of TiO2 with (0 0 4), (1 0 1), and (1 0 5) preferred orientations, while Au-TiO2 presented a tiny XRD peak of Au (111) due to a small Au decorated content of 0.7 ± 0.2 at.%. In addition, the samples obtained a well-defined and uniformed structure of TNAs/TNWs; Au NPs (size of 19.0 ± 1.9 nm) and Au NRs (width of 14.8 ± 1.3 nm and length of 99.8 ± 15.1 nm) were primarily deposited on TNWs top layer; sharp Au/TiO2 interfaces were observed from HRTEM images. The photocurrent density (J) of the photoanode nanomaterials was in the range of 0.24–0.4 mA/cm2. Specifically, Au NPs-NRs- decorated TNWs/TNAs attained the highest J value of 0.4 mA/cm2 because the decoration of Au NPs and Au NRs mixture onto TNWs/TNAs improved the light harvesting capability and the light absorption in the visible-infrared region, enhanced photogenerated carriers’ density, and increased electrons’ injection efficiency via the localized surface plasmon resonance (LSPR) effect occurring at the Au nanostructures. Furthermore, amongst the investigated nanophotocatalysts, the Au NPs-NRs TNWs/TNAs exhibited the highest photocatalytic activity in the degradation of methylene blue with a high reaction rate constant of 0.7 ± 0.07 h−1, which was 2.5 times higher than that of the pristine TNWs/TNAs.
    Materialart: Online-Ressource
    ISSN: 2079-6412
    URL: Article
    DOI: 10.3390/coatings12121957
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2022
    ZDB Id: 2662314-6
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  • 6
    Online-Ressource
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    Telephone-Based Smoking Cessation Counseling Service: Satisfaction and Outcomes in Vietnamese Smokers
    MDPI AG ; 2022
    In:  Healthcare Vol. 11, No. 1 ( 2022-12-31), p. 135-
    Details
    In: Healthcare, MDPI AG, Vol. 11, No. 1 ( 2022-12-31), p. 135-
    Kurzfassung: Background: As a method to acknowledge the devastating health and economic impacts of tobacco usage worldwide, telephone-based tobacco cessation counseling services have emerged as a potential tool to aid people in their quitting process. This study explores the satisfaction of smokers who use the QUITLINE service and factors associated with their quit attempts and cessation. Methods: A cross-sectional survey of 110 participants was conducted from June to July 2016 at the Respiratory Center at Bach Mai Hospital, Hanoi, Vietnam. Multivariate logistic regression was used, and it was found that the percentage of people quitting smoking increased after using the service. Results: In total, 65.5% of participants were completely satisfied with the counseling service. The mean score of staff/s capacity/responsiveness, motivation, and service convenience were 4.37 ± 0.78, 4.30 ± 0.81, and 4.27 ± 0.66, respectively. The smoking relapse rate was relatively high at 58.3%, which mainly resulted from cravings and busy work (26.2% and 14.3%, respectively). A higher satisfaction score in “Staffs’ capacity and responsiveness” was negatively associated with “ever tried to quit smoking in consecutive 24 h” and actually quit smoking after receiving counseling. Meanwhile, a higher score in the “Motivation” domain was positively associated with both quit attempt indicators as well as actually quitting smoking after receiving counseling (OR = 9.48; 95%CI = 2.27; 39.57). Conclusions: These results suggest that it is crucial for decision makers to place more focus on countermeasures for smoking relapse and to strengthen the capacity of staff, especially in motivating clients. Interventions should also be maintained throughout a long period of time to prevent relapse.
    Materialart: Online-Ressource
    ISSN: 2227-9032
    URL: Article
    DOI: 10.3390/healthcare11010135
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2022
    ZDB Id: 2721009-1
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  • 7
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    Helicobacter pylori Infection and Peptic Ulcer Disease in Symptomatic Children in Southern Vietnam: A Prospective Multicenter Study
    MDPI AG ; 2023
    In:  Healthcare Vol. 11, No. 11 ( 2023-06-05), p. 1658-
    Details
    In: Healthcare, MDPI AG, Vol. 11, No. 11 ( 2023-06-05), p. 1658-
    Kurzfassung: Background: Helicobacter pylori (H. pylori) remains a major cause of gastroduodenal diseases. We aimed to evaluate the burden of this infection, particularly peptic ulcer disease in Vietnamese children. Methods: We enrolled consecutive children referred for esophagogastroduodenoscopy at two tertiary children’s hospitals in Ho Chi Minh City, from October 2019 to May 2021. Children treated with proton pump inhibitors during the last two weeks or antibiotics for four weeks, and those having a previous or interventional endoscopy were excluded. H. pylori infection was diagnosed with either a positive culture or positive histopathology combined with a rapid urease test, or with a polymerase chain reaction of the urease gene. The study was approved by the Ethics Committee and written informed consent/assent was obtained. Results: Among 336 enrolled children aged 4–16 (mean: 9.1 ± 2.4 years; 55.4% girls), H. pylori infection was positive in 80%. Peptic ulcers were detected in 65 (19%), increasing with age, and 25% with anemia. cagA+ strains were detected at a higher rate in children with ulcers. Conclusions: Prevalence of H. pylori and peptic ulcers is high among symptomatic Vietnamese children. It is crucial to have a program for early detection of H. pylori to reduce ulcer risk and gastric cancer later.
    Materialart: Online-Ressource
    ISSN: 2227-9032
    URL: Article
    DOI: 10.3390/healthcare11111658
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2023
    ZDB Id: 2721009-1
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  • 8
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    Determinants Influencing the Application of Lean Accounting: The Case of Vietnamese Garment Firms
    MDPI AG ; 2023
    In:  Journal of Risk and Financial Management Vol. 16, No. 5 ( 2023-05-19), p. 279-
    Details
    In: Journal of Risk and Financial Management, MDPI AG, Vol. 16, No. 5 ( 2023-05-19), p. 279-
    Kurzfassung: The shift towards lean production is gradually replacing traditional mass production, and lean accounting is also being mentioned to evaluate operational efficiency based on the lean philosophy, eliminating waste, and simplifying direct cost aggregation along the value stream to improve productivity, distribution, quality, and service. This study aims to evaluate the impact of various factors on the adoption of lean accounting in Vietnamese garment firms based on data collected from 242 survey questionnaires completed by managers and accountants of Vietnamese garment firms. Through Cronbach’s Alpha test, EFA test, and multiple regression analysis to verify and forecast information, eight determinants affecting the adoption of lean accounting in Vietnamese garment firms are arranged in descending order of influence, including leadership, size, cost of implementation, resources, accounting department, education and training, culture, and competitive pressure. Based on the findings, recommendations are proposed to management businesses and agencies to address shortcomings in the process of applying lean accounting, contributing to making it one of the most effective tools in promoting product development and continuous improvement, enhancing quality and production efficiency.
    Materialart: Online-Ressource
    ISSN: 1911-8074
    URL: Article
    DOI: 10.3390/jrfm16050279
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2023
    ZDB Id: 2739117-6
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  • 9
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    Passive Smoking Exposure and Perceived Health Status in Children Seeking Pediatric Care Services at a Vietnamese Tertiary Hospital
    MDPI AG ; 2020
    In:  International Journal of Environmental Research and Public Health Vol. 17, No. 4 ( 2020-02-13), p. 1188-
    Details
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 17, No. 4 ( 2020-02-13), p. 1188-
    Kurzfassung: Understanding the predictors of health conditions and exposure to secondhand smoke among children is necessary to determine the severity of the issues and identify effective solutions. Despite the significant prevalence in smoking and child exposure to secondhand smoke, there have been only a few studies focusing on this area in Vietnam, and thus the current study aims to fill in this gap. The questionnaires of 435 children aged between 0 and 6 and their caregivers, who agreed to participate in the research, were collected at the Pediatric Department of Bach Mai hospital, Hanoi, in 2016. Multivariable logistic regression was employed to identify factors associated with perceived health status and exposure to secondhand smoke among children in the last 24 h and the last 7 days from the date of the survey. Our study found that 43% of the respondents had smokers in the family, and 46.4% of children were exposed to passive smoking in the last 7 days. Urban children were most frequently exposed to passive smoking at home and in public, whereas in the rural area, the home and relatives’ houses were the most common places for exposure. Compared to children whose caregivers were farmers, children of non-government workers were more likely to be exposed to passive smoking in the last 7 days. Moreover, children in a family having smoking rules and no smokers were less likely to be exposed to passive smoking in the last 24 h and 7 days than those living in a family allowing smoking and having smokers. In conclusion, our study shows that the government needs to implement better public smoking monitoring and encourage caregivers to implement smoke-free households or smoking rules in their houses.
    Materialart: Online-Ressource
    ISSN: 1660-4601
    URL: Article
    DOI: 10.3390/ijerph17041188
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2020
    ZDB Id: 2175195-X
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  • 10
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    Analysis of Outbreak and Global Impacts of the COVID-19
    MDPI AG ; 2020
    In:  Healthcare Vol. 8, No. 2 ( 2020-05-29), p. 148-
    Details
    In: Healthcare, MDPI AG, Vol. 8, No. 2 ( 2020-05-29), p. 148-
    Kurzfassung: Corona viruses are a large family of viruses that are not only restricted to causing illness in humans but also affect animals such as camels, cattle, cats, and bats, thus affecting a large group of living species. The outbreak of Corona virus in late December 2019 (also known as COVID-19) raised major concerns when the outbreak started getting tremendous. While the first case was discovered in Wuhan, China, it did not take long for the disease to travel across the globe and infect every continent (except Antarctica), killing thousands of people. Since it has become a global concern, different countries have been working toward the treatment and generation of vaccine, leading to different speculations. While some argue that the vaccine may only be a few weeks away, others believe that it may take some time to create the vaccine. Given the increasing number of deaths, the COVID-19 has caused havoc worldwide and is a matter of serious concern. Thus, there is a need to study how the disease has been propagating across continents by numbers as well as by regions. This study incorporates a detailed description of how the COVID-19 outbreak started in China and managed to spread across the globe rapidly. We take into account the COVID-19 outbreak cases (confirmed, recovered, death) in order to make some observations regarding the pandemic. Given the detailed description of the outbreak, this study would be beneficial to certain industries that may be affected by the outbreak in order to take timely precautionary measures in the future. Further, the study lists some industries that have witnessed the impact of the COVID-19 outbreak on a global scale.
    Materialart: Online-Ressource
    ISSN: 2227-9032
    URL: Article
    DOI: 10.3390/healthcare8020148
    Sprache: Englisch
    Verlag: MDPI AG
    Publikationsdatum: 2020
    ZDB Id: 2721009-1
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