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  • 1
    Online Resource
    Online Resource
    Flexible Fluidic-Type Strain Sensors for Wearable and Robotic Applications Fabricated with Novel Conductive Liquids: A Review
    MDPI AG ; 2022
    In:  Electronics Vol. 11, No. 18 ( 2022-09-13), p. 2903-
    Details
    In: Electronics, MDPI AG, Vol. 11, No. 18 ( 2022-09-13), p. 2903-
    Abstract: Flexible strain sensors with high sensitivity, wide sensing range, and excellent long-term stability are highly anticipated due to their promising potential in user-friendly electronic skins, interactive wearable systems, and robotics. Fortunately, there have been more flexible sensing materials developed during the past few decades, and some important milestones have been reached. Among the various strain sensing approaches, liquid-type (fluidic type) sensing has attracted great attention due to its appealing qualities, including its high flexibility, broad electrochemical window, variety in design, minimal saturated vapor pressure, and outstanding solubility. This review provides the comprehensive and systematic development of fluidic-type flexible strain sensors, especially in the past 10 years, with a focus on various types of liquids used, fabrication methods, channel structures, and their wide-range applications in wearable devices and robotics. Furthermore, it is believed that this work will be of great help to young researchers looking for a detailed study on fluidic strain sensors.
    Type of Medium: Online Resource
    ISSN: 2079-9292
    URL: Article
    DOI: 10.3390/electronics11182903
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662127-7
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  • 2
    Online Resource
    Online Resource
    The Menace of Candida auris Epidemic Amidst the COVID-19 Pandemic: A Systematic Review
    MDPI AG ; 2022
    In:  Diseases Vol. 10, No. 3 ( 2022-08-29), p. 58-
    Details
    In: Diseases, MDPI AG, Vol. 10, No. 3 ( 2022-08-29), p. 58-
    Abstract: Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the causative agent for the Coronavirus Disease 2019 (COVID-19) pandemic, has sparked a medical emergency worldwide. With the rise in COVID-19 infections and an eventual increase in hospitalized critically ill patients, a trend of bacterial, fungal, and viral superinfection has been noted. One important agent of co-infection identified is Candida auris. Due to its multidrug-resistant nature and easy transmissibility, C. auris is difficult to manage in COVID-positive patients. Patients with comorbidities, immunosuppressive states, intubated and on ventilators are more likely to contract the fungal infection. Therefore, it is essential to the first screen, diagnose, and isolate patients with C. auris infection and manage and treat them while preventing the spread of the disease. Failure to recognize and prevent its spread may lead to an eventual epidemic or even a pandemic during the current COVID-pandemic, which the exhausted healthcare system can most definitely not handle. This systematic review investigates the prevalence of C. auris, its pathophysiology, diagnosis, prevention, and treatment during the COVID-19 pandemic.
    Type of Medium: Online Resource
    ISSN: 2079-9721
    URL: Article
    DOI: 10.3390/diseases10030058
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2720869-2
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  • 3
    Online Resource
    Online Resource
    Engineered Extracellular Vesicles for Drug Delivery in Therapy of Stroke
    MDPI AG ; 2023
    In:  Pharmaceutics Vol. 15, No. 9 ( 2023-08-22), p. 2173-
    Details
    In: Pharmaceutics, MDPI AG, Vol. 15, No. 9 ( 2023-08-22), p. 2173-
    Abstract: Extracellular vesicles (EVs) are promising therapeutic modalities for treating neurological conditions. EVs facilitate intercellular communication among brain cells under normal and abnormal physiological conditions. The potential capability of EVs to pass through the blood–brain barrier (BBB) makes them highly promising as nanocarrier contenders for managing stroke. EVs possess several potential advantages compared to existing drug-delivery vehicles. These advantages include their capacity to surpass natural barriers, target specific cells, and stability within the circulatory system. This review explores the trafficking and cellular uptake of EVs and evaluates recent findings in the field of EVs research. Additionally, an overview is provided of the techniques researchers utilize to bioengineer EVs for stroke therapy, new results on EV–BBB interactions, and the limitations and prospects of clinically using EVs for brain therapies. The primary objective of this study is to provide a comprehensive analysis of the advantages and challenges related to engineered EVs drug delivery, specifically focusing on their application in the treatment of stroke.
    Type of Medium: Online Resource
    ISSN: 1999-4923
    URL: Article
    DOI: 10.3390/pharmaceutics15092173
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2527217-2
    SSG: 15,3
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  • 4
    Online Resource
    Online Resource
    Design and Implementation of a Quadruped Amphibious Robot Using Duck Feet
    MDPI AG ; 2019
    In:  Robotics Vol. 8, No. 3 ( 2019-09-05), p. 77-
    Details
    In: Robotics, MDPI AG, Vol. 8, No. 3 ( 2019-09-05), p. 77-
    Abstract: Roaming complexity in terrains and unexpected environments pose significant difficulties in robotic exploration of an area. In a broader sense, robots have to face two common tasks during exploration, namely, walking on the drylands and swimming through the water. This research aims to design and develop an amphibious robot, which incorporates a webbed duck feet design to walk on different terrains, swim in the water, and tackle obstructions on its way. The designed robot is compact, easy to use, and also has the abilities to work autonomously. Such a mechanism is implemented by designing a novel robotic webbed foot consisting of two hinged plates. Because of the design, the webbed feet are able to open and close with the help of water pressure. Klann linkages have been used to convert rotational motion to walking and swimming for the animal’s gait. Because of its amphibian nature, the designed robot can be used for exploring tight caves, closed spaces, and moving on uneven challenging terrains such as sand, mud, or water. It is envisaged that the proposed design will be appreciated in the industry to design amphibious robots in the near future.
    Type of Medium: Online Resource
    ISSN: 2218-6581
    URL: Article
    DOI: 10.3390/robotics8030077
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2662587-8
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