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  • Liga-Inform, Ltd.  (5)
  • 1
    Online Resource
    Online Resource
    Liga-Inform, Ltd. ; 2019
    In:  Klinicheskaia khirurgiia Vol. 86, No. 3 ( 2019-02-28), p. 15-18
    In: Klinicheskaia khirurgiia, Liga-Inform, Ltd., Vol. 86, No. 3 ( 2019-02-28), p. 15-18
    Abstract: Мета. Покращити діагностику та результати лікування хворих з пухлинами прямої кишки шляхом застосування тран- санальної ендоскопічної мікрохірургії і вивчення «сторожових» лімфатичних вузлів. Матеріали і методи. За період з 2009 по 2017 р. у клініці трансанальні ендоскопічні операції виконані 115 хворим у віці від 29 до 82 років. У 92 пацієнтів була тубуловорсинчата аденома прямої кишки, із них у 26 гістологічним дослі- дженням видалених пухлин виявлено малігнізацію (TisN0M0). У 23 пацієнтів до операції виявлено ранній рак прямої кишки Т1–2N0M0.  Результати. У строки спостереження від 12 до 60 міс рецидив виявили у 2 (2,2%) хворих з аденомою і у 3 (13%) з раком прямої кишки. Рецидив раку виник у хворих, які відмовилися від хіміотерапії та променевої терапії. Висновки. Ідентифікація і прицільне дослідження «сторожових» лімфатичних вузлів при раку прямої кишки умож- ливлює вірогідну (чутливість=0,89, специфічність=0,99) оцінку стадії захворювання і застосування адекватної схеми комбінованого і комплексного лікування пацієнтів.
    Type of Medium: Online Resource
    ISSN: 2522-1396 , 0023-2130
    Language: Unknown
    Publisher: Liga-Inform, Ltd.
    Publication Date: 2019
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  • 2
    Online Resource
    Online Resource
    Liga-Inform, Ltd. ; 2022
    In:  Klinicheskaia khirurgiia Vol. 89, No. 7-8 ( 2022-12-23), p. 25-29
    In: Klinicheskaia khirurgiia, Liga-Inform, Ltd., Vol. 89, No. 7-8 ( 2022-12-23), p. 25-29
    Abstract: Objective. To improve intraoperative determination of «sentinel» lymph nodes in patients, suffering mammary gland cancer. Materials and methods. In the 2016 – 2021 yrs period on the base of the Odessa Regional Clinical Hospital 200 patients, suffering mammary gland cancer Stages Т1–Т3N0М0, were operated, using two dyes: the blue patented dye and fluorescent dye indocyanine green. All the patients were distributed into two groups. In Group I in 100 patients the "sentinel" lymph nodes biopsy was conducted. The blue patented dye was used for the lymph nodes staining. The same was conducted in 100 patients of Group II with the "sentinel" lymph nodes biopsy. For the lymph nodes staining there were applied the blue patented dye and fluorescent dye indocyanine green, which were introduced intravenously into the upper extremity on the side of the affected mammary gland along outflow from the upper extremity to mammary gland. Results. General five–year survival after axillary lympho–dissection and after biopsy of «sentinel» lymph nodes have constituted 91 and 92%, accordingly, while recurrence–free five–year survival – 82.2 and 83.9% accordingly. Only in 1.1% patient a regional recurrence in «sentinel» lymph nodes on the affected mammary gland side was revealed. In 57% patients the unaffected «sentinel» lymph nodes were diagnosed, that's why further lympho–dissection was accomplished. In 43% women–patients there was revealed metastatic affection of the lymph nodes. Recurrence was registered in 0.2% patients as an isolated metastases in axillary lymph nodes. Conclusion. The method of the «sentinel» lymph nodes diagnosis in mammary gland cancer, using the dyes, permits to escape the performance of traumatic operations in favor of organ–preserving interventions with biopsy of «sentinel» lymph nodes.
    Type of Medium: Online Resource
    ISSN: 2522-1396 , 0023-2130
    Language: Unknown
    Publisher: Liga-Inform, Ltd.
    Publication Date: 2022
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  • 3
    Online Resource
    Online Resource
    Liga-Inform, Ltd. ; 2022
    In:  Klinicheskaia khirurgiia Vol. 89, No. 11-12 ( 2022-12-30), p. 23-27
    In: Klinicheskaia khirurgiia, Liga-Inform, Ltd., Vol. 89, No. 11-12 ( 2022-12-30), p. 23-27
    Abstract: Objective.To improve the diagnostic biopsy of sentinel lymph nodes in patients, suffering mammary gland cancer, using fluorescent lymphography, and to reduce the quantity of postoperative complications. Materials and methods. In 2016 – 2021yrs period on the base of Odessa Regional Clinical Hospital 400 patients, suffering mammary gland cancer Stages Т1–Т3N0М0, were operated on with application of fluorescent lymphography, using two dyers – the patent blue and indocyanine green. All the patients were distributed into two groups. In Group I (a control one) in 200 patients the sentinel lymph nodes biopsy was performed. The dyer patent blue was applied for the lymph nodes coloring.In Group II (the main) in 200 women–patients the sentinel lymph nodes biopsy, using the patent blue and fluorescent dyer indocyanine green, was performed. Both dyers were injected subdermally along the external areolar edge in the dose 2 ml of the dyer solution. Results. Total 5–year survival after axillary lymphodissection and after the sentinel lymph node biopsy have constituted 91and 92%, accordingly, while the recurrence–free 5–year survival – 82.2 and 83.9%, accordingly. Regional recurrence in sentinel lymph nodes on the affected mammary gland side was diagnosed in 1.1% of the women–patients. In 58% of the women–patients the sentinel lymph nodes were clear, and that’s why a subsequent lymphodissection was not indicated to perform. Metastatic lymph nodes were revealed in 42% of the women–patients. Conclusion. The method of diagnostic biopsy of sentinel lymph nodes in patients, suffering mammary gland cancer, using dyers, permits in majority of them to abandon traumatic operations in favor of organ–preserving interventions, thus reducing the postoperative complications rate significantly.
    Type of Medium: Online Resource
    ISSN: 2522-1396 , 0023-2130
    Language: Unknown
    Publisher: Liga-Inform, Ltd.
    Publication Date: 2022
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  • 4
    Online Resource
    Online Resource
    Liga-Inform, Ltd. ; 2022
    In:  Klinicheskaia khirurgiia Vol. 88, No. 11-12 ( 2022-01-12), p. 11-14
    In: Klinicheskaia khirurgiia, Liga-Inform, Ltd., Vol. 88, No. 11-12 ( 2022-01-12), p. 11-14
    Abstract: Objective. To study іntra- and postoperative complications in transanal endoscopic resection in patients, suffering cancer recti and to reduce this quantity. Materials and methods. Through the period 2009 - 2021 yrs on the base of Odessa Regional Clinical Hospital 184 patients, suffering cancer recti, were operated, using transanal endoscopic resection. The patients’ age was from 42 to 86 yrs old. The patients were distributed into two groups. In 90 patients of the first group the cancer recti diagnosis of stage I (T1-2N0M0) was established. In 94 patients of the second group the diagnosis of cancer recti stage ІІ (T3N0M0) was established. Results. Purulent-septic, thromboembolic and urological complications were absent in all 184 patients, as well as severe intraoperative complications and mortality. The average stationary stay of the patients have constitited (3.4 ± 1.7) days (from 2 to 6 days). The average lower edge of the tumour was situated at a distance (9.5 ± 4.2) cm (from 5 to 16 cm) from the anal channell, and the average dimensions of tumour - (2.8 ± 1.7) cm (from 1.5 to 4 cm). While studying of the histological investigations results there was noted, that in all the patients the tumour was excised in the healthy tissues borders in accordance to oncological technique. Period of follow-up have constituted from 12 to 60 mo. Cancer recti recurrence was revealed in 12 (13.3%) patients of the first group. Cancer recurrence have had occur in patients, who have rejected from conduction of chemo- and radiotherapy. The patients with recurrences were reoperated, using classic low anterior rectal resection with total mesorectumectomy. Conclusion. While conduction of preoperative neoadjuvant chemo- and radiotherapy the tumour dimensions are reduced significantly, as well as quantity of іntra- and postoperative complications in performance of transanal endoscopic resection. The disease prognosis for cancer recti depends directly on presence of metastases in regional «sentinel» lymphatic nodes.
    Type of Medium: Online Resource
    ISSN: 2522-1396 , 0023-2130
    Language: Unknown
    Publisher: Liga-Inform, Ltd.
    Publication Date: 2022
    Location Call Number Limitation Availability
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  • 5
    In: Klinicheskaia khirurgiia, Liga-Inform, Ltd., Vol. 88, No. 3-4 ( 2021-07-28), p. 64-68
    Abstract: Objective. Studying of velocity of prevalence of luminescent dye indocyanine green along lymphatic vessels in the large bowel surgery. Materials and methods. Estimation of procedure for coloring of tumoral substrate and lymphatic vessels while performance of oncological operations was conducted. We performed laparoscopic resection of sigmoid colon in 7 patients, suffering tumors, and anterior rectal resection in 5 patients, having tumors of upper ampullary part of rectum, using indocyanine green dye. Results. In Group I, consisting of 7 patients, surgical technique of no touch manipulations on the tumor before transection of feeding vessels (NTIT–operations) was applied, and in Group II, consisting of 5 patients, the tumor mobilization was done primarily. Application of indocyanine green dye helped a lot to establish localization and prevalence of the process in rectum. Conclusion. Application of fluorescent dye indocyanine green on tumoral substrate before doing ligation of feeding vessels raises possibility of the complication occurrence, consisting of the cancer cells dissemination in abdominal cavity. While performing laparoscopic procedures in resection of the large bowel tumors it is expedient to ligate the feeding vessels primarily, with secondary manipulation– to dissect and mobilize the tumoral substrate.
    Type of Medium: Online Resource
    ISSN: 2522-1396 , 0023-2130
    Language: Unknown
    Publisher: Liga-Inform, Ltd.
    Publication Date: 2021
    Location Call Number Limitation Availability
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