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  • Lahore Medical and Dental College  (5)
  • 1
    Online Resource
    Online Resource
    Molecular Identification of Different Bacteria isolated from Infected Wounds at Hayatabad Medical Complex Peshawar Pakistan
    Lahore Medical and Dental College ; 2022
    In:  Pakistan Journal of Medical and Health Sciences Vol. 16, No. 4 ( 2022-04-26), p. 875-877
    Details
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 16, No. 4 ( 2022-04-26), p. 875-877
    Abstract: Wound infections are one of the most common hospital acquired infections and are an important cause of morbidity and account for 70-80% mortality. The Purpose of the current study was to determine the commonest bacteria associated with wound infections at Hayatabad Medical Complex Peshawar January 2019 to June 2020. A total of 100 culture positive samples from patients with mean age of 6.2+0.25 were analyzed. Patient history and clinical findings were collected on a pre-coded form. Pus samples or wound swabs were collected from infected wounds and were analyzed through culturing and biochemical methods for aerobic bacteria. A total of 109 bacteria were isolated from 100 samples with almost same frequency of Gram positive cocci 54(49.54%) and Gram negative bacilli 55(50.45%). Most frequently isolated organism was S. aureus 45(41.28%) followed by Pseudomonas species 20(18.35%).From this study we conclude that Wound infection remains an ongoing problem which, although, cannot be completely eradicated, however by taking prompt control measures against the most commonly isolated organism and proper care of wound may lead to the minimum of wound infection. Keywords: Abscess, wound infection, padiatric surgical wounds, arobic bacteria
    Type of Medium: Online Resource
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.53350/pjmhs22164
    DOI: 10.53350/pjmhs2216
    DOI: 10.53350/pjmhs22164875
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2022
    Location Call Number Limitation Availability
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  • 2
    Online Resource
    Online Resource
    Multi-Drug Resistance of Escherichia coli (E.coli) Isolated from Clinical Isolates in District Peshawar Kp Pakistan
    Lahore Medical and Dental College ; 2022
    In:  Pakistan Journal of Medical and Health Sciences Vol. 16, No. 1 ( 2022-01-30), p. 830-835
    Details
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 16, No. 1 ( 2022-01-30), p. 830-835
    Abstract: Multidrug-resistant Escherichia coli have become a main public health distress in Pakistan and many countries, causing failure in treatment with the resultingenormous health burden. The current study was aimed to find the prevalence of E. coli among clinical isolates and their antibiotics susceptibility pattern using standard procedures. The Purpose of the present study to investigate the Prevalence and antibiotic susceptibility pattern of E. coli detected from clinical patients visiting Khyber teaching hospital Peshawar. In this study a total 415 sample were isolated from the patient of Khyber teaching hospital (KTH) Peshawar. The collected samples were processed for identification including Gram staining and biochemical test. Furthermore, the antibiotic susceptibility pattern of all the positive strains of E. coli was tested using selected antibiotic discs by disc diffusion method as per CLSI guidelines 2019.A total of 415 samples, 112 clinical isolates yielded the growth of E. coli using standard procedures. Out of 112 isolates, 52% were recovered from male patients while 60% were females. The positive samples were obtained from urine (58%), pus (14.3%), swab (8.9%), sputum (10.7%), and others 8.0% respectively. The highest sensitive drugs are FOS (99.1%), AK (98.2%), TZP (97.3%), MEM (93.8%), TGC (91.1%), CN (89.3%), SCF (78.6%), DO (65.2%), CT (60.7%), F (49.1%), ATM (27.7%) AMP (23.2%), CAZ (23.2%), CPM (22.3%) , CRO (19.6%) ,CTX (13.4%) and the lowest sensitive drug is CIP which is (7.1%) . The drugs which show high resistance are CIP (92.9%), CTX (86.6%), CRO (80.4%), CPM (77.7%), CAZ (76.8%), AMP (76.8%) , ATM (72.3%) , CT( 39.3%) , DO (34.8%), SCF (21.4%), CN(10.7%),TGC(8.9%), F(8.9%),MEM(6.3%) ,TZP(2.7%),AK (1.8%) ,and the lowest resistance drug is FOS (0.9%).Drug resistance monitoring and the epidemiological analysis of patient data are needed regularly and can be useful for the adequate management of antimicrobial resistance. Key words: Multidrug-resistant, Antimicrobial Resistance, Clinical Isolates, Bacteria, Peshawar
    Type of Medium: Online Resource
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.53350/pjmhs22161
    DOI: 10.53350/pjmhs2216
    DOI: 10.53350/pjmhs22161830
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2022
    Location Call Number Limitation Availability
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  • 3
    Online Resource
    Online Resource
    Evaluation of the Remdesivir Treatment of Non-Hospitalized Patients with COVID-19
    Lahore Medical and Dental College ; 2022
    In:  Pakistan Journal of Medical and Health Sciences Vol. 16, No. 6 ( 2022-06-30), p. 1043-1045
    Details
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 16, No. 6 ( 2022-06-30), p. 1043-1045
    Abstract: Novel corona virus 2019 has resulted in a pandemic which killed over five million people worldwide. It causes acute respiratory syndrome and is reported to affect multi-organ system. Various variant of corona virus (COVID-19) has been emerged in various regions of the world as a result of mutation in original strains. The Purpose of the Current Study to evaluate the effect of Remdesivir for treating non-hospitalized patients with COVID-19 at the Department of Medicine PIMS Hospital from 1st January 2021 to 30th June 2021. In the Current Research One hundred patients were enrolled and divided into group A and group B within the age of 24-70 years. Group A was receiving Remdesivir while group B is not receiving Remdesivir. The clinical variables, BMI, Comorbidities, duration of disease severity and viral load were determined. RT-PCR was conducted to determine viral load. The mean age of study participants was 50±15 years with greater number of males. Diabetes was the major comorbidity. The time duration was decreased in group A upto 5 days and 8 days in group B. The viral load was decreased by mean value 6.32±1.76 to 6.2±1.78 in group B then group A respectively and result show that Remdesivir is effective in COVID-19 treatment. Keywords: Remdesivir, COVID-19, Viral load
    Type of Medium: Online Resource
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.53350/pjmhs22166
    DOI: 10.53350/pjmhs2216
    DOI: 10.53350/pjmhs221661043
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2022
    Location Call Number Limitation Availability
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  • 4
    Online Resource
    Online Resource
    Molecular and Epidemiological Evaluation of Liver Function Diagnosis between Different Genotypes of HBV and HCV in Non-Responders of HBV-HCV Co-Infected Patients with Healthy Controls
    Lahore Medical and Dental College ; 2022
    In:  Pakistan Journal of Medical and Health Sciences Vol. 16, No. 3 ( 2022-03-31), p. 827-829
    Details
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 16, No. 3 ( 2022-03-31), p. 827-829
    Abstract: Hepatitis B and C co-infection may leads to cirrhosis resulting in hepatocellular carcinoma with poorer survival rate. Pegylated interferon and ribavirin treatment is considered as gold standard. Despite of adequate treatment, some patients remained nonresponders. Due to this reason, this study was designed to compare different parameters of liver function tests along with HBV- HCV genotyping in non-responders of HBV-HCV co-infection with normal controls. Study population was divided in two groups. Group A (patient group) includes 30 HBV-HCV co-infected patients and Group B (control group).includes 30 normal individuals. Blood samples of both groups were collected. Samples were analyzed for HBV and HCV genotyping using automated kits of Abbott laboratories and Liver Functions testing (ALT, ALP, Bilirubin, Albumin) using ROCHE COBAS-501 automated system. Statistical analysis using chi-square test for ordinal data and t-test for numerical data was used using p value. Key words: Hepatitis B, Hepatitis C, Viral infection, Viral resistant, Biochemical test, genotyping in retroviruses infected patients
    Type of Medium: Online Resource
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.53350/pjmhs22163
    DOI: 10.53350/pjmhs2216
    DOI: 10.53350/pjmhs22163827
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2022
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  • 5
    Online Resource
    Online Resource
    Epidemiological Features of Cutaneous Leishmaniasis in Hilly and Plot Areas of Tribal Districts, Khyber-Pakhtunkhwa Province Pakistan
    Lahore Medical and Dental College ; 2022
    In:  Pakistan Journal of Medical and Health Sciences Vol. 16, No. 2 ( 2022-02-26), p. 1132-1136
    Details
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 16, No. 2 ( 2022-02-26), p. 1132-1136
    Abstract: Cutaneous Leishmaniasis is caused by flagellated parasitic protozoans of the genus Leishmania and is spread by vectors. This is a new threat that is endemic to the tropics and subtropics and has a broad geographic distribution. The current research was carried out in all tribal districts of Khyber Pakhtunkhwa province to 2020. The prevalence of Cutaneous Leishmaniasis was found to be higher in children aged 5 to 10 years old in the current research, due to a weakened immune system. In the province, 23 species of phlebotomine sand-flies belonging to the genera Phlebotomus Sergentomyia and grassomiya were discovered. Cutaneous Leishmaniasis is caused by flagellated parasitic protozoans of the genus Leishmania, which are transmitted via the bite of a mosquito. This is an emergent threat and endemic in areas of tropic and sub-tropics and has the epidemiological aspects of Cutaneous Leishmaniasis during the recent epidemic in tribal districts of Khyber Pakhtunkhwa in 2020. The suspected patients of Leishmaniasis from different areas of tribal districts were examined. We came across 700 cases during 3-month period from may to july2020. A major portion G2 ([41.1%; n = 290) of these patients were in age 6 to–10 years. The infection rate was higher in male (75.3%; n = 525) compared to females (25%;n = 125). Both gender and age showed a significant effect on the occurrence of infection. The current study report CL outbreak in the tribal districts of Khyber Pakhtunkhwa which need immediate response from the healthcare authorities. In addition, extensive awareness campaigns are needed for timely prevention of such outbreak. Keywords: Cutaneous Leishmaniasis, outbreak
    Type of Medium: Online Resource
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.53350/pjmhs22162
    DOI: 10.53350/pjmhs2216
    DOI: 10.53350/pjmhs221621132
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2022
    Location Call Number Limitation Availability
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