In:
The Korean Journal of Parasitology, Korean Society for Parasitology, Vol. 58, No. 1 ( 2020-02-29), p. 61-65
Abstract:
Majority of the imported malaria cases in Korea is attributed to 〈 i 〉 Plasmodium falciparum 〈 /i 〉 and 〈 i 〉 P. vivax 〈 /i 〉 infections, whereas 〈 i 〉 P. malariae 〈 /i 〉 and 〈 i 〉 P. ovale 〈 /i 〉 infections are very rare. Falciparum and ovale malaria are mostly imported from Africa, while most of the vivax malaria cases are imported from Southeast Asia. Here, we report 6 Korean imported ovale malaria cases (4 males and 2 females) who had visited in Africa during 2013-2016. These subjects were diagnosed with 〈 i 〉 P. ovale 〈 /i 〉 based on microscopic findings, 〈 i 〉 Plasmodium 〈 /i 〉 species-specific nested-PCR, and phylogenetic clade using 18S rRNA gene sequences. We identified 2 〈 i 〉 P. ovale 〈 /i 〉 subtypes, 1 〈 i 〉 P. ovale curtisi 〈 /i 〉 (classic type) and 5 〈 i 〉 P. ovale wallikeri 〈 /i 〉 (variant type). All patients were treated with chloroquine and primaquine, and no relapse or recrudescence was reported for 1 year after treatment. With increase of travelers to the countries where existing Plasmodium species, the risk of 〈 i 〉 Plasmodium 〈 /i 〉 infection is also increasing. Molecular monitoring for imported malaria parasites should be rigorously and continuously performed to enable diagnosis and certification of 〈 i 〉 Plasmodium 〈 /i 〉 spp.
Type of Medium:
Online Resource
ISSN:
0023-4001
,
1738-0006
DOI:
10.3347/kjp.2020.58.1.61
Language:
English
Publisher:
Korean Society for Parasitology
Publication Date:
2020
detail.hit.zdb_id:
2163174-8
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