In:
Endocrinology and Metabolism, Korean Endocrine Society, Vol. 35, No. 4 ( 2020-12-31), p. 901-908
Abstract:
Background: The aim of this study was to evaluate clinical outcomes in coronavirus disease 2019 (COVID-19) positive patients with type 2 diabetes compared to those without diabetes in Korea.Methods: We extracted claims data for patients diagnosed with COVID-19 from the National Health Insurance Service database in Korea from January 20, 2020 to March 31, 2020. We followed up this cohort until death from COVID-19 or discharge from hospital.Results: A total of 5,473 patients diagnosed with COVID-19 were analyzed, including 495 with type 2 diabetes and 4,978 without diabetes. Patients with type 2 diabetes were more likely to be treated in the intensive care unit (ICU) (P 〈 0.0001). The incidence of inhospital mortality was higher in patients with type 2 diabetes (P 〈 0.0001). After adjustment for age, sex, insurance status, and comorbidities, odds of ICU admission (adjusted odds ratio [OR], 1.59; 95% confidence interval [CI] , 1.02 to 2.49; 〈 i 〉 P 〈 /i 〉 =0.0416) and in-hospital mortality (adjusted OR, 1.90; 95% CI, 1.13 to 3.21; 〈 i 〉 P 〈 /i 〉 =0.0161) among patients with COVID-19 infection were significantly higher in those with type 2 diabetes. However, there was no significant difference between patients with and without type 2 diabetes in ventilator, oxygen therapy, antibiotics, antiviral drugs, antipyretics, and the incidence of pneumonia after adjustment.Conclusion: COVID-19 positive patients with type 2 diabetes had poorer clinical outcomes with higher risk of ICU admission and in-hospital mortality than those without diabetes. Therefore, medical providers need to consider this more serious clinical course when planning and delivering care to type 2 diabetes patients with COVID-19 infection.
Type of Medium:
Online Resource
ISSN:
2093-596X
,
2093-5978
DOI:
10.3803/EnM.2020.787
Language:
English
Publisher:
Korean Endocrine Society
Publication Date:
2020
detail.hit.zdb_id:
2802452-7
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