In:
Physiological Research, Institute of Physiology of the Czech Academy of Sciences
Abstract:
We have recently developed a simple method of plasma free DNA detection, which enables us to distinguish between apoptotic and genomic (necrotic) DNA. After applying this method to the critically ill, we revealed apoptotic DNA on the day of admission to be higher than later when multiple-organ failure developed. Moreover, apoptotic DNA contributed to total plasma DNA much more than DNA from necrotic cells and its increase predicted future development of multiple-organ failure and death.
Type of Medium:
Online Resource
ISSN:
1802-9973
,
0862-8408
DOI:
10.33549/physiolres.930803
Language:
English
Publisher:
Institute of Physiology of the Czech Academy of Sciences
Publication Date:
2005
detail.hit.zdb_id:
2100162-5
SSG:
12
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