In:
Bioscience, Biotechnology, and Biochemistry, Informa UK Limited, Vol. 80, No. 6 ( 2016-06-02), p. 1179-1185
Abstract:
The antioxidant potencies of chondroitin sulfates (CSs) from shark cartilage, salmon cartilage, bovine trachea, and porcine intestinal mucosa were compared by three representative methods for the measurement of the antioxidant activity; DPPH radical scavenging activity, superoxide radical scavenging activity, and hydroxyl radical scavenging activity. CSs from salmon cartilage and bovine trachea showed higher potency in comparison with CSs from shark cartilage and porcine intestinal mucosa. Next, CS from salmon cartilage chelating with Ca2+, Mg2+, Mn2+, or Zn2+ were prepared, and their antioxidant potencies were compared. CS chelating with Ca2+ or Mg2+ ions showed rather decreased DPPH radical scavenging activity in comparison with CS of H+ form. In contrast, CS chelating with Ca2+ or Mg2+ ion showed remarkably enhanced superoxide radical scavenging activity than CS of H+ or Na+ form. Moreover, CS chelating with divalent metal ions, Ca2+, Mg2+, Mn2+, or Zn2+, showed noticeably higher hydroxyl radical scavenging activity than CS of H+ or Na+ form. The present results revealed that the scavenging activities of, at least, superoxide radical and hydroxyl radical were enhanced by the chelation with divalent metal ions.
Type of Medium:
Online Resource
ISSN:
0916-8451
,
1347-6947
DOI:
10.1080/09168451.2016.1141036
Language:
English
Publisher:
Informa UK Limited
Publication Date:
2016
detail.hit.zdb_id:
2110940-0
SSG:
12
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