In:
Advances in Natural Sciences: Nanoscience and Nanotechnology, IOP Publishing, Vol. 3, No. 1 ( 2012-03-01), p. 015006-
Abstract:
In this study magnetic fluids were manufactured by the adsorption of chitosan (CS) and O-carboxymethyl chitosan (OCMCS) on Fe 3 O 4 nanoparticles to be used as hyperthermic thermoseeds. Fe 3 O 4 particles were characterized by physico-chemical methods such as: thermogravimetry analysis (TGA), x-ray diffraction (XRD), Raman spectrum, Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM) and vibrating sample magnetometer (VSM). The SEM images and XRD patterns showed that the synthesized Fe 3 O 4 nanoparticles were of single phase and spherical shape with 10–15 nm in diameter. The VSM measurements showed that Fe 3 O 4 particles were superparamagnetic with saturation magnetization of 70 emu g −1 . The adsorbed layers of CS and OCMCS on the magnetite surface ( Fe 3 O 4 / CS ) and ( Fe 3 O 4 / OCMCS ) were confirmed by FTIR, Raman spectra and SEM. In the ac magnetic field of 80 Oe and 236 kHz, the saturation heating temperatures of the sample Fe 3 O 4 / CS and Fe 3 O 4 / OCMCS were 100 and 98 ° C , respectively. At the same concentration of Fe 3 O 4 nanoparticles in suspension, the two magnetic fluids exhibited quite high heating capacity, with different behaviors of concentration dependence. The Fe 3 O 4 / CS and Fe 3 O 4 / OCMCS nanoparticles would serve as good thermoseeds for localized hyperthermia treatment of cancers.
Type of Medium:
Online Resource
ISSN:
2043-6262
DOI:
10.1088/2043-6262/3/1/015006
Language:
Unknown
Publisher:
IOP Publishing
Publication Date:
2012
detail.hit.zdb_id:
2563789-7
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