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  • Hue University of Medicine and Pharmacy  (51)
  • 1
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    Assessing the readiness of medical students for blended learning model using virtual reality
    Hue University of Medicine and Pharmacy ; 2022
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Background: Assessing students’ learning readiness has become more important to establish on-target learning and teaching environments, particularly since blended learning and online learning are widely implemented in medical education. This study aims (1) to examine the reliability and validity of Online Learning Readiness Scale (OLRS) and (2) to identify the levels of online learning readiness for blended learning methods using virtual reality and its associations. Methods: A cross-sectional study with 102 fifthyear medical students was conducted. The data were analyzed through exploratory factor analysis and confirmatory factor analysis. Pearson correlation analysis was utilized to investigate the relationships among dimensions of OLRS. Results: The VN-version of the OLRS scale consists of 16 items in four dimensions, namely Self-directed learning - SDL, Motivation for learning - MFL, Computer & Internet self-efficacy - CIS, Online communication self-efficacy - OCS. Confirmatory factor analysis indicates the model fit of the OLRS scale in a blended learning course context. The composite reliability and construct validity of the scale was found to be within the acceptable range. Students showed high readiness for blended learning course, of which SDL was the dimension having the highest score of readiness, followed by MFL and CIS dimensions. There were positive correlations across all dimensions of OLRS (p 〈 0.001). Statistically significant associations were found between gender, health professional orientation, computer self-efficacy and their experience of medical education environment and dimensions of OLRS. Conclusion: The results indicate that the OLRS is a reliable and valid measurement tool in the assessment of online learning readiness levels of blended learning course using virtual reality. It is recommended to develop a reliable scale to assess the perceptions and readiness of instructors undertaking the move to blended teaching. Key words: confirmatory factor analysis, blended learning, Online Learning Readiness Scale, virtual reality, medical education
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2022.5.26
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2022
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  • 2
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    EVALUATION OF THE SEDATIVE EFFECT OF PROPOFOL IN COMBINATION WITH FENTANYL IN COLONOSCOPY
    Hue University of Medicine and Pharmacy ; 2021
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Background: Colonoscopy is one of the most common procedures. Sedation and analgesia decrease anxiety and discomfort and minimize risks. Therefore, patients prefer to be sedated in examination. Until now, there is no known drug that is ideal for sedation during colonoscopy. Recently, Propofol is an intravenous hypnotic with rapid onset and short duration of action, thus, propofol has assumed a prominent position.The combination propofol with opioids are used to relieve the patient’s pain and discomfort. Objectives: Comparison of propofol alone in combination with different doses of fentanyl to find the most effective dose for sedation in colonoscopy. Methods: In a prospective, randomized clinical study, 120 patients who underwent colonoscopy at the Hue University of Medicine and Pharmacy Hospital. Patients in this study were divided into three groups: Group I received intravenous fentanyl (0.5 mcg/kg) 2-3 min followed by propofol (1.5 mg/kg) IV; Group II received fentanyl (1.0 mcg/kg) 2-3 min followed by propofol (1.5 mg/kg) IV; Group III received intravenous anesthesia propofol (1.5 mg/kg). If the patient is awake during endoscopy, bolus propofol 0.5 mg/kg. The study variables included: pulse, blood pressure, oxygen saturation, quality of sedation, total dose of propofol used, number of awakenings, time to resuscitation, patient and endoscopist satisfaction, side effects of sedation such as slow pulse, low blood pressure, respiratory failure, nausea,.... Results: Patients in Group II had either lower incidence of reaction (motor or verbal) to the colonoscopyintroduction or lower propofol consumption but awaking-time was longer. The time from stop propofol until the patient was awake was longer in group 2 than in group 1 and group 3. Group 2 reached the desired level of sedation faster than group 1 and group 3. Other results was not different between three groups. Conclusion: The combination of fentanyl (1.0 mcg/kg) and propofol (1.5 mg/kg) for colonoscopy sedation reduces propofol consumption and provides greater result. Key words: Colonoscopy, fentanyl, propofol.
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2021.5.7
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2021
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  • 3
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    AMPLIFICATION AND OVEREXPRESSION OF HER2/NEU IN GASTRIC CANCER ASSESSED BY FLUORESCENCE IN SITU HYBRIDIZATION AND IMMUNOHISTOCHEMISTRY
    Hue University of Medicine and Pharmacy ; 2015
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Background: HER2/neu is a predictive biomarker for treatment of gastric cancer using trastuzumab in combination with chemotherapy. This study aimed to: (1) assess the amplification and the overexpression of HER2/neu using fluorescence in situ hybridization (FISH) and immunohistochemistry in gastric cancer; (2) survey the association between HER2/neu and clinicopathologic characteristics of gastric cancer. Patients and methods: one hundred and sixty gastric cancer patients were assessed HER2/neu overexpression by IHC using Ventana anti-HER-2/neu (4B5) kit and were assessed HER2/neu gene amplification by FISH using PathVysionTM HER-2 DNA Probe kit with biopsy specimens. Results: HER2/neu protein expression rates of IHC 0, 1+, 2+ and 3+ were 70%, 10.6%, 10.6% and 8.8%, respectively. HER2/neu gene amplification was identified in gastric cancer from 21 out of 160 (13.1%) patients. The concordance between IHC and FISH was 90.0%. The HER2/neu-positive rate assessed by both techniques was 13.1%. There was a significant difference in HER2/neu-positivity between cardia gastric cancer and non-cardia gastric cancer (36.4% vs 11.4%, p = 0.040); between intestinal type and diffuse type (20.7% vs 5.9%, p = 0.010); between well, moderately differentiated and poorly differentiated gastric cancer (18.6% and 23.8% vs 5.8%, p = 0.047). Conclusion: We applied successfully FISH and IHC technique with biopsy samples in gastric cancer detecting HER2/neu positivity in order to select patients that benefit from trastuzumab in combination with chemotherapy. HER2/neu status associated with tumor location, Lauren classification and differentiated grading. Keywords: gastric cancer, fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), HER-2/neu
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2015.3.3
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2015
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  • 4
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    Propofol infusion for sedated upper gastrointestinal endoscopic ultrasound: a comparison of propofol alone versus propofol-fentanyl or propofol-midazolam
    Hue University of Medicine and Pharmacy ; 2023
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Background: Gastrointestinal (GI) endoscopic untrasound is the major technique for diagnosis of GI disease and treatment. Various sedation and analgesia regimens such as midazolam, fentanyl, and propofol can be used during GI endoscopy. The purpose of the study was to compare propofol alone and propofol combine with midazolam or fentanyl in moderate sedation for GI endoscopy. Objectives: To observe the efficiency comparison between propofol alone and propofol/fentanyl or propofol/midazolam on sedation during upper gastrointestinal endoscopic ultrasound. Methods: In a prospective, randomized clinical study, 90 patients were assigned to group 1 (n = 30; 1 mg/kg IV propofol) group 2 (n = 30; 1 mg IV midazolam intravenous followed 1 mg/kg IV propofol) or group 3 (n = 30; 50 μg fentanyl followed 1 mg/kg IV propofol). Each patient was administered 1 mg/kg propofol for induction. All of the patients were administered an additional dose of IV propofol infusion (5 mg/kg/h). This study was performed in Hue University of Medicine and Pharmacy Hospital, between January 2020 - 2021. Total propofol consumption, time to achieve, physician and patient satisfaction scores, and instances of side effects, such as bradycardia and hypotension were recorded. Postprocedural records included recovery time, postoperative adverse events (nausea, vomiting, dizziness, recall, and pain) and satisfaction. Results: The average propofol consumption was 283.8 ± 113 mg in Group 1 and 230 ± 76.3 mg in Group 2 and 231.8 ± 76.3 mg in Group 3 (p 〈 0.05). The incidence of moving motor or verbal) was lower in Group 3 (p 〈 0.05). The physician satisfaction was higher significantly in Group 3 (p 〈 0.05). Total propofol consumption was higher in group 1 significantly. Time to onset of sedation was significantly higher in group 1 The physician satisfaction was higher significantly in Group 3. Overall, the other results were similar in 3 groups. Conclusion: Both propofol/fentanyl and propofol/midazolam combinations provided appropriate hypnosis and analgesia during upper gastrointestinal endoscopy. However, propofol consumption was significantly lower and greater endoscopist satisfaction in group using the propofol/ fentanyl combination. Key words: sedation, upper gastrointestinal endoscopy, propofol, fentanyl, midazolam
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2023.2.19
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2023
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  • 5
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    TO STUDY OF CHARACTERISTICS OF OBJECTIVE MULTIPLE-CHOICE TEST FOR MEDICAL MODULES
    Hue University of Medicine and Pharmacy ; 2020
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Background: The objective multiple-choice test is an assessment method that has been applied widely in universities. The meticulous judgment of complication and differentiation level of objective test questionnaire can beneficially lead to the growth of high quality multiple-choice questionnaire bank and effective examination. Objectives: To evaluate the difficulty level and differentiate level of the objective multiple-choice tests. Materials and method: The multiple-choice theory test (01 Elemental medical exam with 242 students, 01 Clinical medicine exam with 163 students). The difficulty degree of questions was determined by calculating the percentage of students who gave the answers correctly for the given questions in total. The differentiation level was differentiated by the percentage of students who answered correctly in corresponding groups: excellent, good, average, below average, poor. Results: The elemental medical examination comprises 7 hard questions, 58 medium questions, and 35 simple questions; 10 questions have poor degree of difference, 83 questions have good and very good degree of difference. The clinical medicine examination comprises 9 hard questions, 57 medium questions and, 34 simple questions; 23 questions have poor degree of differentiation, 51 questions have good and very good degree of difference. Conclusions: It is crucial to evaluate the difficulty and differentiation standards of the objective multiple-choice examination which enhance the quality of assessment. Thereby, the faculties need to regularly judge these factors while creating the questionnaire and completely evaluating the tests, and the inappropriate questions will be eliminated. Keywords: difficulty level, differentiation level, Objective multiple-choice test.
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2020.6.12
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2020
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  • 6
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    POST-DURAL PUNCTURE HEADACHE AND RISK FACTORS IN WOMEN UNDERGOING CESAREAN SECTION WITH SPINAL ANESTHESIA
    Hue University of Medicine and Pharmacy ; 2019
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Objective: To estimate the incidence of post-dural puncture headache (PDPH) and risk factors in women underwent Cesarean section with spinal anesthesia. Materials and method: In a prospective descriptive study, parturients underwent Cesarean section with spinal anesthesia. Incidence of post-dural puncture headache, the history of spinal anesthesia and PDPH, presence of headache, preeclampsia, migraine, sinusitis, caffeine withdraw, insertion site, repeated puncture attempts, direction of the needle, size of the needle, local anesthesic, perioperative hypotension, nausea and vomiting, amount of intravenous fluid were recorded. Results: There were 389 patients in the study. The incidence of PDPH was 14.65% (mild and moderate pain: 75.44%; severe pain 21.05%; worst pain: 3.51%). The risk factors were history of PDPH (OR = 4.5; 95% CI: 1.8 - 11.09), sinusitis (OR = 2.65; 95% CI: 1.10 - 6.36), local anesthesia (Marcain spinal 0.5% heavy) (OR = 6.66; 95% CI: 2.25 - 19.11), perioperative hypotension (OR = 2.42; 95% CI: 1.25 - 4.70). Conclusion: The incident of PDPH in women undergoing Cesarean section with spinal anesthesia was 14.65%. Four risk factors were the history of PDPH, sinusitis, local anesthesia (Marcain spinal 0.5% heavy) and perioperative hypotension. Key words: post-dural puncture headache (PDPH), Cesarean section, spinal anesthesia
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2019.4.5
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2019
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  • 7
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    PREVALENCE OF DEPRESSION AND THE ASSOCIATED FACTORS AMONG THE ELDERLY IN SOME COMMUNITIES OF THUA THIEN HUE PROVINCE
    Hue University of Medicine and Pharmacy ; 2021
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Introduction: Currently, Vietnam is entering the aging population stage and is one of the fastest aging countries worldwide. Old age increases the risk of chronic diseases, particularly mental health disorders. Objective: investigated the prevalence of depression and examined the associated factors with depression among older people. Methods: A cross-sectional study was implemented in 760 older people in some communities of Thua Thien Hue province from January to August 2020. Data were collected by directinterviewing based on a structured questionnaire, including demographic, socio-economic, geriatric Depression scale with 30 questions (GDS-30), health status and physical activities. The GDS-30 was used to evaluate the prevalence of depression. The multiple logistic regression model was applied to exam the associated factors with depression. Results: Our findings indicated that the prevalence of depression among elderly people was 28.6%, comprising mild (23.6%) and seveve (5%). The higher Odds of depression was observed in the low economic status (poor/near-poor) (OR= 2.51; 95% CI: 1.15 – 5.48), live alone (OR= 2.43; 95% CI: 1.02-5.78), co-morbidities chronic disease(OR =1,59; 95% CI: 1.01 – 2.52), self-evaluation not good in overall health status (OR =2.34; 95% CI: 1,50 – 3,66), dissatisfaction in health (OR = 2.55; 95% CI:1.59 – 4.08), lack of physical activities (OR =2.79; 95% CI: 1.83 - 4.27), and low quality of life (OR = 2.79; 95% CI: 1.84-4.24). Conclusions: This research suggests that older people are commonly exposing to depression in the communities. Therefore, the priority strategies for reducing depression should be implemented, particularly in the high-risk groups.
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2021.2.9
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2021
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  • 8
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    SURVEY ON CHARACTERISTICS CLINICAL OF DYSMENORRHEA AND THE NEED FOR TREATMENT WITH TRADITIONAL MEDICINE OF FEMALE STUDENTS OF HUE UNIVERSITY OF MEDICINE AND PHARMACY
    Hue University of Medicine and Pharmacy ; 2021
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Background: Dysmenorrhea is understood as a woman suffering from menstrual pain. Dysmenorrhea is often manifested with symptoms such as abdominal pain, back pain, vomiting, nausea, diarrhea, dizziness,... it not only causes physical pain for the patient, expensive treatment, but also greatly affects the quality of life. Objective: To stduy characteristics of dysmenorrhea and the need for treatment with traditional medicine of female students of Hue university of medicine and pharmacy. Materials and method: A crosssectional descriptive study was conducted in 409 female students from 8 academic majors at Hue University of Medicine and Pharmacy. Students were instructed and completed a self-administered questionnaire, using the Cox Retrospective Symptom Scale (RSS –Cox) to assess menstrual symptoms, using the VAS pain severity scale to assess the level of pain. Result: The rate of dysmenorrhea among female students of Hue University of Medicine and Pharmacy was 88.8%. Moderate pain (according to VAS) accounts for 51.8%, mild pain 30.3% and severe pain 17.9%. The average RSS-Cox1 score was 16.7 ± 10.6 and the RSS-Cox 2 score was 13.0 ± 9.5. According to traditional medicine, Excess accounts for 65.3%, Deficiency 47.9%, Heat 3.0% and Cold 51.8%. In clinical type, the pattern of stagnation of cold-dampness accounts for 38.3%, stagnation of Qi and blood stasis 30.9%, deficiency of Qi and blood 18.7% deficiency of the liver and kidney 10.5%. The proportion of students who need for treatment with traditional medicine is 14.9%, acupress massage and moxibustion are the two methods with the highest demand for treatment. Conclusion: The rate of dysmenorrhea among female students at Hue University of Medicine and Pharmacy is high, most of them have moderate pain, and menstrual-related symptoms appear more often with quite severe levels. According to traditional medicine, most of them have the manifestations of Excess and Cold, corresponding to stagnation of cold-dampness and stagnation of Qi and blood stasis are higher than the others. Demand for treatment of dysmenorrhea with traditional medicine is relatively low, most of them need treatment with acupress massage and moxibustion methods. Key words: dysmenorrhea, the need for treatment, female students, Hue university of medicine and pharmacy
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2021.1.11
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2021
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  • 9
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    PRENATAL DIAGNOSIS FOR TRISOMY 21, 18 AND 13 BY QUANTITATIVE FLUORESCENT POLYMERASE CHAIN REACTION AMONG PREGNANT WOMEN WITH HIGH RISK
    Hue University of Medicine and Pharmacy ; 2018
    In:  Journal of Medicine and Pharmacy Vol. 8, No. 4 ( 2018-8), p. 88-95
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy, Vol. 8, No. 4 ( 2018-8), p. 88-95
    Abstract: Introduction: Prenatal diagnosis of trisomy 21, 18 and 13 plays a very important role in the improving population quality. This study was aimed at (1) Identifying the prevalence of trisomy 21, 18 and 13 by QFPCR from amniotic cells of high-risk pregnancies; and (2) Evaluating the association between diagnosed trisomies and some characteristics of mother and fetus. Objectives and methods: 170 pregnant women with high risk of having trisomy 21, 18 or 13 fetuses during first trimester screening (gestation age from 11 weeks to 13 weeks 6 days). DNA was extracted from amniocytes for prenatal diagnosis using QF-PCR. Results: The prevalence of trisomies was 9.4%, among which trisomy 21 and trisomy 18 accounted for 68.8% and 31.2%, respectively; none of them was trisomy 13. There was the significant association between diagnosed trisomies and maternal age (cut-off 30.5 years old) and nuchal translucency thickness (cut-off 1.95 mm). MoM median of free β-hCG increased in trisomy 21 group (4.35, p = 0.021) and decreased in trisomy 18 group (0.13, p 〈 0.001) as compared to the non-trisomy group (2.28). MoM median of serum PAPP-A decreased in trisomy 18 group (0.14, p = 0.004) as compared to the non-trisomy group (0.54). Conclusion: Prenatal diagnosis by QF-PCR detected remarkable prevalence of fetuses with trisomy 21 và 18. There was the significant association between diagnosed trisomies and maternal age, nuchal translucency thickness, free β-hCG and serum PAPP-A. Key words: prenatal diagnosis, trisomy, QF-PCR
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Issue
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp.2018
    DOI: 10.34071/jmp.2018.4
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2018.4.13
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2018
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  • 10
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    A PILOT STUDY OF HER-2/NEU GENE AMPLIFICATION ASSESSED BY FLUORESCENCE IN SITU HYBRIDIZATION (FISH) IN GASTRIC CANCER
    Hue University of Medicine and Pharmacy ; 2014
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Background: HER-2/neu is a predictive biomarker for treatment of gastric cancer using trastuzumab in combination with chemotherapy. This study aimed to evaluate the status of HER-2/neu gene amplification using fluorescence in situ hybridization (FISH) in gastric cancer. Patients and methods: thirty six gastric cancer patients were assessed HER-2/neu gene amplification by FISH using PathVysionTM HER-2 DNA Probe kit (including HER-2/neu probe and CEP-17 probe) with biopsy and surgical specimens. Results: The HER-2/neu gene amplification was observed in three cases (8.3%), the HER-2/neu gene amplification rate in Lauren’s intestinal-type and diffuse-type were 11.8% and 5.2%, respectively. Conclusion: We applied successfully FISH technique with gastric cancer tissue samples. This technique could be performed as routine test in gastric cancer in order to select patients that benefit from trastuzumab in combination with chemotherapy.
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2014.3.2
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2014
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