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  • Hindawi Limited  (23)
  • 1
    In: BioMed Research International, Hindawi Limited, Vol. 2019 ( 2019-05-02), p. 1-13
    Abstract: Purpose . The aim of this study was to assess the treatment-related factors associated with local recurrence and overall survival of patients with osteosarcoma treated with limb-salvage surgery. Patients and Methods . Treatment-related factors were analyzed to evaluate their effects on local recurrence-free survival (LRFS) and overall survival (OS) in 182 patients from 2004 to 2013. Results . The mean length of follow-up was 73.4 ± 34.7 months (median, 68 months; range, 12-173 months), and 63 patients died by the end of the follow-up. The 5-year and 10-year overall survival rates were 68.6 ± 6.6% and 59.4 ± 10.6%, respectively. Univariate analysis showed that treatment-related prognostic factors for overall survival were prolonged symptom intervals 〉 =60 days, biopsy/tumor resection performed by different centers, previous medical history, incomplete preoperative chemotherapy ( 〈 8 weeks), and prolonged postoperative interval 〉 21 days. In the multivariate analysis, biopsy/tumor resection performed by different centers, incomplete implementation of planned new adjuvant chemotherapy, and delayed resumption of postoperative chemotherapy ( 〉 21 days) were risk factors for poor prognosis; biopsy/tumor resection performed by different centers and tumor necrosis 〈 90% were independent predictors of local recurrence. Conclusion . For localized osteosarcoma treated with limb-salvage surgery, it is necessary to optimize timely standard chemotherapy and to resume postoperative chemotherapy to improve survival rates. Biopsies should be performed at experienced institutions in cases of developing local recurrence.
    Type of Medium: Online Resource
    ISSN: 2314-6133 , 2314-6141
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2019
    detail.hit.zdb_id: 2698540-8
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  • 2
    In: Shock and Vibration, Hindawi Limited, Vol. 2020 ( 2020-10-26), p. 1-15
    Abstract: The electrostatic force nonlinearity caused by fringe effects of the microscale comb will affect the dynamic performance of the micromechanical vibrating gyroscopes (MVGs). In order to reveal the influence mechanism, a class of four-degree-of-freedom (4-DOF) electrostatically driven MVG is considered. The influence of DC bias voltage and comb spacing on the nonlinearity of electrostatic force and the dynamic response of the MVG by using multiple time scales method and numerical simulation are discussed. The results indicate that the electrostatic force nonlinearity causes the system to show stiffness softening. The softening characteristics of the electrostatic force cause the offset of the resonance frequency and a decrease in sensitivity. Although the electrostatic nonlinearity has a great influence on the dynamic behaviour, its influence can be avoided by the reasonable design of the comb spacing and DC bias voltage. There exists a critical value for comb spacing and DC bias voltage. In this paper, determining the critical values is demonstrated by nonlinear dynamics analysis. The results can be supported by the finite element analysis and numerical simulation.
    Type of Medium: Online Resource
    ISSN: 1875-9203 , 1070-9622
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2020
    detail.hit.zdb_id: 2070162-7
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  • 3
    In: BioMed Research International, Hindawi Limited, Vol. 2019 ( 2019-02-25), p. 1-11
    Abstract: Objectives . Ankylosing spondylitis (AS) is a chronic disease that decreases mobility, function, and quality of life. This study introduced the “Smart-phone SpondyloArthritis Management System” (SpAMS), an interactive mobile health (mHealth) tool designed for AS/spondyloarthritis (SpA) disease management and used SpAMS data to evaluate clinical characteristics of Chinese patients with AS. Methods . SpAMS integrates patient’s and physician’s portals in a smart phone application. The Chinese Ankylosing Spondylitis Prospective Imaging Cohort was launched using SpAMS in April 2016. Patient self-assessments were completed online at baseline and at every subsequent clinic visit. Physician-reported assessments and treatments were recorded by rheumatologists during each visit. Results . In total, 1201 patients with AS [mean (SD) age, 30.6 (8.7) years; male, 82.6%] were recruited. Mean (SD) disease duration was 8.4 (6.1) years. Past or current symptoms of acute anterior uveitis (AAU), psoriasis, and inflammatory bowel disease (IBD) were observed in 21.0%, 3.7%, and 9.4% of patients, respectively. AAU and IBD occurred significantly more in patients with symptom duration 〉 10 years. The most commonly used medications at baseline were nonsteroidal anti-inflammatory drugs (98.2%). Patients using tumour necrosis factor inhibitors accounted for 20.8%, and 66.4% of patients used conventional synthetic disease-modifying antirheumatic drugs. At baseline, 57.2% of patients had inactive disease (ID)/low disease activity (LDA); this rate significantly improved to 79.2% after a mean follow-up of 13.3 (5.9) months. Compared with relapsed patients, new achievers of ID/LDA underwent more online patient assessments ( P 〈 .001). Problems solved in SpAMS caused 29.1% of clinic visits to a tertiary hospital unnecessary. SpAMS saved an average of 5.3 hours and 327.4 RMB per person on traffic expenses; these expenses equalled 16% of the Chinese monthly disposable personal income. Conclusions . SpAMS is a time- and cost-saving disease management tool that can help patients with AS perform self-management and provide valuable data to clinicians.
    Type of Medium: Online Resource
    ISSN: 2314-6133 , 2314-6141
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2019
    detail.hit.zdb_id: 2698540-8
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  • 4
    Online Resource
    Online Resource
    Hindawi Limited ; 2023
    In:  Journal of Food Processing and Preservation Vol. 2023 ( 2023-6-12), p. 1-13
    In: Journal of Food Processing and Preservation, Hindawi Limited, Vol. 2023 ( 2023-6-12), p. 1-13
    Abstract: In this manuscript, polysaccharide (TMSP) was isolated from Trichosanthes kirilowii Maxim. seed shell. The homogeneous polysaccharide (TMSP-1; molecular weight: 690.239 kDa) was purified by column chromatography (DEAE-cellulose-52 and Sephadex G-150). The result of monosaccharide composition showed that TMSP-1 consisted of D-mannose, D-glucose, D-galactose, and glucuronic acid in a molar ratio of 2.01 : 1.98 : 1.87 : 1. Methylation analysis showed that TMSP-1 was made up of →3)-D-Galp-(1→, D-Glcp-(1→, →4)-D-Manp-(1→, →6)-D-Galp-(1→, →4)-D-Galp-(1→, and →4,6)-D-Manp-(1→. The microscopic conformation of TMSP-1 showed a regular flake-like structure that was inlaid with small holes. The α-glucosidase inhibitory rate of TMSP-1 reached 52.23% when the concentration of TMSP-1 was 8 mg/mL, which confirmed the potential hypoglycemic activity of TMSP-1 in vitro. In vivo results showed that type 2 diabetes causes a significant increase in organ index and TMSP-1 recovered the organ index in mice ( P 〈 0.05 ). Furthermore, TMSP-1 reversed the increase of liver and kidney weight and the indicators of abnormality. This research lays a foundation for research on the polysaccharides of Trichosanthes kirilowii Maxim. seed shell in hypoglycemia.
    Type of Medium: Online Resource
    ISSN: 1745-4549 , 0145-8892
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2023
    detail.hit.zdb_id: 2175273-4
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  • 5
    Online Resource
    Online Resource
    Hindawi Limited ; 2017
    In:  Applied Bionics and Biomechanics Vol. 2017 ( 2017), p. 1-8
    In: Applied Bionics and Biomechanics, Hindawi Limited, Vol. 2017 ( 2017), p. 1-8
    Abstract: Existing corn harvester cutting blades have problems associated with large cutting resistance, high energy consumption, and poor cut quality. Using bionics principles, a bionic blade was designed by extracting the cutting tooth profile curve of the B. horsfieldi palate. Using a double-blade cutting device testing system, a single stalk cutting performance contrast test for corn stalks obtained at harvest time was carried out. Results show that bionic blades have superior performance, demonstrated by strong cutting ability and good cut quality. Using statistical analysis of two groups of cutting test data, the average cutting force and cutting energy of bionic blades and ordinary blades were obtained as 480.24 N and 551.31 N and 3.91 J and 4.38 J, respectively. Average maximum cutting force and cutting energy consumption for the bionic blade were reduced by 12.89% and 10.73%, respectively. Variance analysis showed that both blade types had a significant effect on maximum cutting energy and cutting energy required to cut a corn stalk. This demonstrates that bionic blades have better cutting force and energy consumption reduction performance than ordinary blades.
    Type of Medium: Online Resource
    ISSN: 1176-2322 , 1754-2103
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2017
    detail.hit.zdb_id: 2179924-6
    SSG: 12
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  • 6
    Online Resource
    Online Resource
    Hindawi Limited ; 2022
    In:  Shock and Vibration Vol. 2022 ( 2022-3-7), p. 1-10
    In: Shock and Vibration, Hindawi Limited, Vol. 2022 ( 2022-3-7), p. 1-10
    Abstract: In this study, the vibration acceleration and radiation structure noise in specific points, 30 cm away from the center surface of each plate of the concrete deck, web, and flange of the steel beam, are measured via the hammering test. The test is conducted on the middle concrete deck of an 8.5 m steel-concrete composite slab beam. The accuracy of the numerical model is then carefully justified. The influence of the number of shear studs, spacing, and arrangement of ribs on the concerning results is methodically examined and discussed by employing the numerical model. In the center frequency of 10–1000 Hz, the total sound power level of the structure can be lessened by improving the concrete deck thickness as well as the number of shear studs. The reduction of the rib spacing can effectively lessen the sound power level as well. The noise reduction of the plate with rib arrangement in the midspan zone is more influential than the case with uniform layout in the whole span.
    Type of Medium: Online Resource
    ISSN: 1875-9203 , 1070-9622
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2070162-7
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  • 7
    Online Resource
    Online Resource
    Hindawi Limited ; 2020
    In:  Advances in Civil Engineering Vol. 2020 ( 2020-12-27), p. 1-11
    In: Advances in Civil Engineering, Hindawi Limited, Vol. 2020 ( 2020-12-27), p. 1-11
    Abstract: With the concept of smart geogrid coming out, many scholars have built optical fiber into the geogrid to form a kind of smart geogrid material with self-sensing function of structural deformation. It can not only reinforce the parts with potential safety hazards, but also have the functions of safety monitoring, intelligent prevention, and control of engineering disasters, which is of great significance for ensuring the safety of tunnel construction and improving the tunnel monitoring methods. Based on predecessors’ research on smart geogrid tensile calibration experiment and sensor method simulation and experimental verification, this paper analyzes the smart geogrid and the tunnel surrounding rock as a whole, to study the deformation coordination mechanism between the geogrid material and the tunnel surrounding rock. Referring to the relevant engineering practice case, through finite element numerical simulation, the optimal layout of smart geogrid material was explored, and the principle of discrete curvature reconstruction curve sensing of smart geogrid was optimized by simulating the working conditions of different construction methods and supporting conditions, in order to provide a theoretical basis for the application of smart geogrid material in practical tunnel engineering.
    Type of Medium: Online Resource
    ISSN: 1687-8094 , 1687-8086
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2020
    detail.hit.zdb_id: 2449760-5
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  • 8
    Online Resource
    Online Resource
    Hindawi Limited ; 2018
    In:  Advances in Civil Engineering Vol. 2018 ( 2018), p. 1-11
    In: Advances in Civil Engineering, Hindawi Limited, Vol. 2018 ( 2018), p. 1-11
    Abstract: A new cement-based mortar with high early strength and toughness was developed by adding micro steel fibers (MSF) in magnesium phosphate cement (MPC) mortar. The compressive and flexural tests were carried out to investigate the effect of curing time, MSF volume fraction, sand-cement mass ratio, and water-cement mass ratio on the strength and flexural toughness of MSF-reinforced MPC mortar (MSFRMM). Also, the flexural toughness and ductility of MSFRMM were evaluated according to ASTM C1609. The results of this study showed that the addition of MSF from 0% to 1.6% by volume significantly improved the compressive strength of MSFRMM. The MSFRMM showed high early strength, especially during the first 3 days. The addition of MSFs changed the flexural failure mode of MPC-based mortar from brittleness to ductility, and the flexural toughness of MSFRMM remarkably increased with the increase of MSF volume fraction from 0% to 1.6%. The toughness and ductility of MSFRMM slightly increased with the increase of the dosage of cement. The toughness and ductility of MSFRMM increased with the decrease of the water-cement mass ratio due to the improved density of the mortar caused by the reduction of water.
    Type of Medium: Online Resource
    ISSN: 1687-8086 , 1687-8094
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2018
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  • 9
    Online Resource
    Online Resource
    Hindawi Limited ; 2021
    In:  Wireless Communications and Mobile Computing Vol. 2021 ( 2021-3-14), p. 1-9
    In: Wireless Communications and Mobile Computing, Hindawi Limited, Vol. 2021 ( 2021-3-14), p. 1-9
    Abstract: The lack of traffic data is a bottleneck restricting the development of Intelligent Transportation Systems (ITS). Most existing traffic data completion methods aim at low-dimensional data, which cannot cope with high-dimensional video data. Therefore, this paper proposes a traffic data complete generation adversarial network (TDC-GAN) model to solve the problem of missing frames in traffic video. Based on the Feature Pyramid Network (FPN), we designed a multiscale semantic information extraction model, which employs a convolution mechanism to mine informative features from high-dimensional data. Moreover, by constructing a discriminator model with global and local branch networks, the temporal and spatial information are captured to ensure the time-space consistency of consecutive frames. Finally, the TDC-GAN model performs single-frame and multiframe completion experiments on the Caltech pedestrian dataset and KITTI dataset. The results show that the proposed model can complete the corresponding missing frames in the video sequences and achieve a good performance in quantitative comparative analysis.
    Type of Medium: Online Resource
    ISSN: 1530-8677 , 1530-8669
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2045240-8
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  • 10
    In: Advances in Civil Engineering, Hindawi Limited, Vol. 2022 ( 2022-3-18), p. 1-19
    Abstract: The production processes for the gypsum- and cement-based materials, which are widely used in civil engineering projects, require the consumption of large amounts of energy and natural resources. At the present time, the main development directions of civil engineering material include realizing solid waste recycling and the applications of green building materials, which can be then used in the fields of disaster treatment and ecological restoration, such as grouting materials. In addition, the grouting quality is always difficult to detect. This study examined the gypsum- and cement-based green grouting materials made from mineral solid waste used in disaster and cloud detection by means of electromagnetic characteristics. According to the requirements of electrical testing of grouting quality, first we designed a material made with solid waste. Then, we studied the resistivity, strength, porosity, and other physical and mechanical properties of the material. The test results of the material and its soaking solution indicate that this material is a green material meeting the environmental safety standards. The experimental results show that the rapid detection of grouting quality can be realized. The following effects on electromagnetic characteristics and mechanical properties of the green materials of gypsum- and cement-based were analyzed. The results showed that the resistivity and strength were related to the ratios of the water content to the modified phosphogypsum; the percentages of cement content in the total amount of modified phosphogypsum and marble powder; the percentages of marble powder in the modified phosphogypsum; the percentages of steel fiber content in the phosphogypsum; and the fineness of the marble powder. The field test results also confirm that the green grouting material can be effectively applied in engineering repair imaging monitoring.
    Type of Medium: Online Resource
    ISSN: 1687-8094 , 1687-8086
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2449760-5
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