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  • Hindawi Limited  (94)
  • 1
    Online Resource
    Online Resource
    A Study of Developing a System Dynamics Model for the Learning Effectiveness Evaluation
    Hindawi Limited ; 2013
    In:  Mathematical Problems in Engineering Vol. 2013 ( 2013), p. 1-6
    Details
    In: Mathematical Problems in Engineering, Hindawi Limited, Vol. 2013 ( 2013), p. 1-6
    Abstract: This study used the research method of system dynamics and applied the Vensim software to develop a learning effectiveness evaluation model. This study developed four cause-and-effect chains affecting learning effectiveness, including teachers’ teaching enthusiasm, family involvement, school’s implementation of scientific activities, and creative teaching method, as well as the system dynamics model based on the four cause-and-effect chains. Based on the developed system dynamic model, this study performed simulation to investigate the relationship among family involvement, learning effectiveness, teaching achievement, creative teaching method, and students’ learning interest. The results of this study verified that there are positive correlations between family involvement and students’ learning effectiveness, as well as students’ learning effectiveness and teachers’ teaching achievements. The results also indicated that the use of creative teaching method is able to increase students’ learning interest and learning achievement.
    Type of Medium: Online Resource
    ISSN: 1024-123X , 1563-5147
    URL: Article
    DOI: 10.1155/2013/298621
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2013
    detail.hit.zdb_id: 2014442-8
    SSG: 11
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  • 2
    Online Resource
    Online Resource
    Molecular detection and phylogenetic analysis of Porcine circovirus 4 in Henan and Shanxi Provinces of China
    Hindawi Limited ; 2021
    In:  Transboundary and Emerging Diseases Vol. 68, No. 2 ( 2021-03), p. 276-282
    Details
    In: Transboundary and Emerging Diseases, Hindawi Limited, Vol. 68, No. 2 ( 2021-03), p. 276-282
    Type of Medium: Online Resource
    ISSN: 1865-1674 , 1865-1682
    URL: Issue
    URL: Article
    DOI: 10.1111/tbed.v68.2
    DOI: 10.1111/tbed.13714
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2414822-2
    SSG: 22
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  • 3
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    Online Resource
    On Generalized Transitive Matrices
    Hindawi Limited ; 2011
    In:  Journal of Applied Mathematics Vol. 2011 ( 2011), p. 1-16
    Details
    In: Journal of Applied Mathematics, Hindawi Limited, Vol. 2011 ( 2011), p. 1-16
    Abstract: Transitivity of generalized fuzzy matrices over a special type of semiring is considered. The semiring is called incline algebra which generalizes Boolean algebra, fuzzy algebra, and distributive lattice. This paper studies the transitive incline matrices in detail. The transitive closure of an incline matrix is studied, and the convergence for powers of transitive incline matrices is considered. Some properties of compositions of incline matrices are also given, and a new transitive incline matrix is constructed from given incline matrices. Finally, the issue of the canonical form of a transitive incline matrix is discussed. The results obtained here generalize the corresponding ones on fuzzy matrices and lattice matrices shown in the references.
    Type of Medium: Online Resource
    ISSN: 1110-757X , 1687-0042
    URL: Article
    DOI: 10.1155/2011/164371
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2011
    detail.hit.zdb_id: 2578385-3
    SSG: 17,1
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  • 4
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    Online Resource
    Analysis of the Evacuation Capacity of Parallel Double Running Stairs in Different Merging Form Based on Simulation
    Hindawi Limited ; 2018
    In:  Discrete Dynamics in Nature and Society Vol. 2018 ( 2018-07-15), p. 1-14
    Details
    In: Discrete Dynamics in Nature and Society, Hindawi Limited, Vol. 2018 ( 2018-07-15), p. 1-14
    Abstract: In order to analyze the evacuation capacity of parallel double running stairs, a dozen stairs merging forms are set by investigation and statistics, and the improved agent-based evacuation model that considers the merging behavior is used to simulate the process of merging and evacuation in the stairs. The stairs evacuation capacity is related to the evacuation time and the robustness of stairs, and the evacuation time can be calculated by using the improved agent-based model based on computer simulation. The robustness of each merging form can be obtained according to the fluctuation degree of evacuation time under the different pedestrian flow. The evaluation model of stairs evacuation capacity is established by fusing the evacuation time and the robustness of stairs. Combined with the specific example to calculate the evacuation capacity of each stairs form, it is found that every merging form has different evacuation time and different robustness, and the evacuation time has not positive correlation with the robustness for the same form stairs. Meanwhile, the evacuation capacity of stairs is not related to the number of the floor entrances. Finally, the results show that the evacuation capacity of stairs is optimal when the floor entrances are close to out stairs in parallel double running stairs and suitable to the case where pedestrian flow and the change of pedestrian flow are large.
    Type of Medium: Online Resource
    ISSN: 1026-0226 , 1607-887X
    URL: Article
    DOI: 10.1155/2018/3541420
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2018
    detail.hit.zdb_id: 2033014-5
    SSG: 11
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  • 5
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    Online Resource
    Correlation between FBN1 mutations and ocular features with ectopia lentis in the setting of Marfan syndrome and related fibrillinopathies
    Hindawi Limited ; 2021
    In:  Human Mutation Vol. 42, No. 12 ( 2021-12), p. 1637-1647
    Details
    In: Human Mutation, Hindawi Limited, Vol. 42, No. 12 ( 2021-12), p. 1637-1647
    Type of Medium: Online Resource
    ISSN: 1059-7794 , 1098-1004
    URL: Issue
    URL: Article
    DOI: 10.1002/humu.v42.12
    DOI: 10.1002/humu.24283
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 1498165-8
    SSG: 12
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  • 6
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    Brain MR Image Classification for Alzheimer’s Disease Diagnosis Based on Multifeature Fusion
    Hindawi Limited ; 2017
    In:  Computational and Mathematical Methods in Medicine Vol. 2017 ( 2017), p. 1-13
    Details
    In: Computational and Mathematical Methods in Medicine, Hindawi Limited, Vol. 2017 ( 2017), p. 1-13
    Abstract: We propose a novel classification framework to precisely identify individuals with Alzheimer’s disease (AD) or mild cognitive impairment (MCI) from normal controls (NC). The proposed method combines three different features from structural MR images: gray-matter volume, gray-level cooccurrence matrix, and Gabor feature. These features can obtain both the 2D and 3D information of brains, and the experimental results show that a better performance can be achieved through the multifeature fusion. We also analyze the multifeatures combination correlation technologies and improve the SVM-RFE algorithm through the covariance method. The results of comparison experiments on public Alzheimer’s Disease Neuroimaging Initiative (ADNI) database demonstrate the effectiveness of the proposed method. Besides, it also indicates that multifeatures combination is better than the single-feature method. The proposed features selection algorithm could effectively extract the optimal features subset in order to improve the classification performance.
    Type of Medium: Online Resource
    ISSN: 1748-670X , 1748-6718
    URL: Article
    DOI: 10.1155/2017/1952373
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2017
    detail.hit.zdb_id: 2256917-0
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  • 7
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    Online Resource
    The Efficacy of 18F-FDG PET/CT and Superparamagnetic Nanoferric Oxide MRI in the Diagnosis of Lung Cancer and the Value of 18F-FDG PET/CT in the Prediction of Lymph Node Metastasis
    Hindawi Limited ; 2021
    In:  Computational and Mathematical Methods in Medicine Vol. 2021 ( 2021-9-11), p. 1-7
    Details
    In: Computational and Mathematical Methods in Medicine, Hindawi Limited, Vol. 2021 ( 2021-9-11), p. 1-7
    Abstract: In China, lung cancer is one of the leading causes of death among residents. Early diagnosis is of great significance for early interventional treatment and prolonging survival. PET/CT uses positron radiopharmaceuticals to observe the physiological and biochemical changes of the drug and its metabolites in the body and finally diagnoses the disease. 18F-FDG is a commonly used imaging agent, but its short isotopic half-life limits clinical high-throughput testing. This study retrospectively analyzed the imaging material of 100 lung cancer patients pathologically confirmed. Patients with lymph node metastasis were classified into the LM group ( n = 30 cases), and those with no lymph node metastasis were classified into the NLM group ( n = 70 cases). The results showed that MRI of superparamagnetic nanoferric oxide was better than diagnosis of lung cancer by the 18F-FDG PET/CT and had a high predictive power for lymph node metastasis. These turned out to be high-value lung cancer diagnosis of superparamagnetic nanoferric oxide MRI and high-capacity lymph node metastasis prediction of 18F-FDG PET/CT, which were worthy of implementation.
    Type of Medium: Online Resource
    ISSN: 1748-6718 , 1748-670X
    URL: Article
    DOI: 10.1155/2021/2448782
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2256917-0
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  • 8
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    Online Resource
    Neuroprotective Properties of Panax notoginseng Saponins via Preventing Oxidative Stress Injury in SAMP8 Mice
    Hindawi Limited ; 2017
    In:  Evidence-Based Complementary and Alternative Medicine Vol. 2017 ( 2017), p. 1-7
    Details
    In: Evidence-Based Complementary and Alternative Medicine, Hindawi Limited, Vol. 2017 ( 2017), p. 1-7
    Abstract: Inhibiting oxidative damage in early stage of Alzheimer’s disease (AD) is considered as a strategy for AD treatment. Our previous study has shown that Panax notoginseng saponins (PNS) have an antiaging action by increasing the levels of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-PX) in the serum of aged rats. In this study, we aimed to investigate the effects of PNS on antioxidant enzymes and uncoupling proteins (UCPs) involved in oxidative stress in AD mice. The results showed that PNS prevented neuronal loss in hippocampal CA1 region and alleviated pathomorphological change of neurons in CA1 region. Moreover, PNS inhibited the production of 8-hydroxydeoxyguanosine (8-OHdG), enhanced the expressions and activities of SOD, CAT, and GSH-PX, and improved the mRNA and protein levels of UCP4 and UCP5 in the brains of SAMP8 mice. Together, our study shows that PNS has the ability to protect neurons in AD brain from oxidative stress damage through attenuating the production of 8-OHdG, enhancing the activities of antioxidant enzymes and the expressions levels of UCP4 and UCP5. Accordingly, PNS may be a promising agent for AD treatment.
    Type of Medium: Online Resource
    ISSN: 1741-427X , 1741-4288
    URL: Article
    DOI: 10.1155/2017/8713561
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2017
    detail.hit.zdb_id: 2148302-4
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  • 9
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    Cestrum nocturnum Flower Extracts Attenuate Proliferation and Induce Apoptosis in Malignant Cells through Inducing DNA Damage and Inhibiting Topoisomerase II Activity
    Hindawi Limited ; 2017
    In:  Evidence-Based Complementary and Alternative Medicine Vol. 2017 ( 2017), p. 1-8
    Details
    In: Evidence-Based Complementary and Alternative Medicine, Hindawi Limited, Vol. 2017 ( 2017), p. 1-8
    Abstract: Most of the existing chemotherapeutic drugs have plenty of side effects. Chinese herbal medicine has been used for pharmaceutical and dietary therapy for thousands of years with more effective and fewer side effects. Cestrum nocturnum (CN) has long been used to treat digestive diseases for centuries in China. Our previous study first proved that the n-butanol part isolated from the flowers of CN produced an inhibitory effect on the proliferation of malignant cells. However, the fractions responsible for the antiproliferation effect of n-butanol part from CN flowers and related mechanisms remain unknown. Thus, in this study, we extracted fractions C4 and C5 from n-butanol part of CN flowers and investigated their immune toxicity and antitumor activities. It was found that fractions C4 and C5 exhibited great cytotoxicity to cancer cell lines but had low immune toxicity towards T and B lymphocytes in vitro. The tested fractions also attenuated proliferation and induced apoptosis at G 0 /G 1 and G 2 /M phases in Bel-7404 cells through inducing DNA damage and inhibiting topoisomerase II relaxation activity. These results suggest that fractions C4 and C5 may represent important sources of potential antitumor agents due to their pronounced antitumor effects and low immune toxicity.
    Type of Medium: Online Resource
    ISSN: 1741-427X , 1741-4288
    URL: Article
    DOI: 10.1155/2017/1456786
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2017
    detail.hit.zdb_id: 2148302-4
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  • 10
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    Online Resource
    Luhong Formula Has a Cardioprotective Effect on Left Ventricular Remodeling in Pressure-Overloaded Rats
    Hindawi Limited ; 2020
    In:  Evidence-Based Complementary and Alternative Medicine Vol. 2020 ( 2020-05-30), p. 1-15
    Details
    In: Evidence-Based Complementary and Alternative Medicine, Hindawi Limited, Vol. 2020 ( 2020-05-30), p. 1-15
    Abstract: Background . Luhong formula (LHF)—a traditional Chinese medicine containing Cervus nippon Temminck, Carthamus tinctorius L., Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao, Codonopsis pilosula (Franch.) Nannf., Cinnamomum cassia Presl, and Lepidium apetalum Willd—is used in the treatment of heart failure, but little is known about its mechanism of action. We have investigated the effects of LHF on antifibrosis. Methods . Forty-eight SD male rats were randomly assigned into six groups ( n  = 8), model group, sham-operation group, perindopril group (0.036 mg/ml), LHF high doses (LHF-H, 1.44 g/mL), LHF middle doses (LHF-M, 0.72 g/mL), and LHF low doses (LHF-L, 0.36 g/mL). Except the sham-operation group, the other groups were received an abdominal aorta constriction to establish a model of myocardial hypertrophy. The HW and LVW were measured to calculate the LVW/BW and HW/BW. ELISA was used to detect the serum concentration of BNP. The expressions of eNOS, TGF- β 1, caspase-3, VEGF, and VEGFR2 in heart tissues were assessed by western blot analysis. mRNA expressions of eNOS, Col1a1, Col3a1, TGF- β 1, VEGF, and VEGFR2 in heart tissues were measured by RT-PCR. The specimens were stained with hematoxylin-eosin (HE) and picrosirius red staining for observing the morphological characteristics and collagen fibers I and III of the myocardium under a light microscope. Results . LHF significantly lowered the rat’s HW/BW and LVM/BW, and the level of BNP in the LHF-treated group compared with the model group. Histopathological and pathomorphological changes of collagen fibers I and III showed that LHF inhibited myocardial fibrosis in heart failure rats. Treatment with LHF upregulated eNOS expression in heart tissue and downregulated Col1a1, Col3a1, TGF- β 1, caspase-3, VEGF, and VEGFR2 expression. Conclusion . LHF can improve left ventricular remodeling in a pressure-overloaded heart failure rat model; this cardiac protective ability may be due to cardiac fibrosis and attenuated apoptosis. Upregulated eNOS expression and downregulated Col1a1, Col3a1, TGF- β 1, caspase-3, VEGF, and VEGFR2 expression may play a role in the observed LHF cardioprotective effect.
    Type of Medium: Online Resource
    ISSN: 1741-427X , 1741-4288
    URL: Article
    DOI: 10.1155/2020/4095967
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2020
    detail.hit.zdb_id: 2148302-4
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