In:
Computational and Mathematical Methods in Medicine, Hindawi Limited, Vol. 2012 ( 2012), p. 1-8
Abstract:
Resting state functional connectivity of MEG data was studied in 29 children (9-10 years old). The weighted phase lag index (WPLI) was employed for estimating connectivity and compared to coherence. To further evaluate the network structure, a graph analysis based on WPLI was used to determine clustering coefficient ( C ) and betweenness centrality (BC) as local coefficients as well as the characteristic path length ( L ) as a parameter for global interconnectedness. The network’s modular structure was also calculated to estimate functional segregation. A seed region was identified in the central occipital area based on the power distribution at the sensor level in the alpha band. WPLI reveals a specific connectivity map different from power and coherence. BC and modularity show a strong level of connectedness in the occipital area between lateral and central sensors. C shows different isolated areas of occipital sensors. Globally, a network with the shortest L is detected in the alpha band, consistently with the local results. Our results are in agreement with findings in adults, indicating a similar functional network in children at this age in the alpha band. The integrated use of WPLI and graph analysis can help to gain a better description of resting state networks.
Type of Medium:
Online Resource
ISSN:
1748-670X
,
1748-6718
Language:
English
Publisher:
Hindawi Limited
Publication Date:
2012
detail.hit.zdb_id:
2256917-0
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