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  • Hindawi Limited  (27)
  • 1
    In: Journal of Chemistry, Hindawi Limited, Vol. 2014 ( 2014), p. 1-7
    Abstract: Clay-brine process employing activated clay, NaCl, HCl, and HF as raw materials is the primarily advanced technology to synthesize cryolite in the present industrial grade. However, plenty of byproducts of fluorine-containing waste HCl at the concentration of about 10%~12% could not be utilized comprehensively and are even hazardous to the environment. This work proposed a new two-step technology to prepare inorganic polymer flocculants polyaluminium chloride (PAC) from synthetic cryolite mother liquor. Many specific factors such as the variety of aluminide source, reaction temperature and time, reagent ratio, and manner of alkaline addition were taken into consideration and their influences on the performances of produced PAC were discussed. It was found that synthetic cryolite mother liquor could react with bauxite and calcium aluminate directly to prepare cheap PAC, with plenty amount of water insoluble CaF 2 and CaSiF 6 produced as well. However, once HCl was introduced into synthetic cryolite mother liquor as well as by utilizing bauxite as aluminide source and sodium aluminate as adjusting basicity agent, the resultant PAC would dissolve out higher amount of aluminum while producing little amount of water insoluble materials. The coagulation behavior of the specially produced PAC could even match the industrial grade PAC conforming to national standard.
    Type of Medium: Online Resource
    ISSN: 2090-9063 , 2090-9071
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2014
    detail.hit.zdb_id: 2393625-3
    detail.hit.zdb_id: 2703077-5
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  • 2
    Online Resource
    Online Resource
    Hindawi Limited ; 2016
    In:  Journal of Nanomaterials Vol. 2016 ( 2016), p. 1-10
    In: Journal of Nanomaterials, Hindawi Limited, Vol. 2016 ( 2016), p. 1-10
    Abstract: To widen the application of nanofibers web in the field of medical health materials, a new Ag/amino-terminated hyperbranched polymer (HBP)/polyacrylonitrile (PAN) nanofiber web with excellent antimicrobial activity and filtration property was produced with Ag/HBP dispersion solution and PAN nanofiber. Ag/HBP dispersion solution was prepared with HBP as reducer and stabilizer, and Ag/HBP/PAN nanofiber was prepared by modifying electrospun PAN nanofiber with Ag/HBP aqueous solution. The characterization results showed that spherical Ag nanoparticles were prepared and they had a narrow distribution in HBP aqueous solution. The results of Ag/HBP/PAN nanofiber characterized with SEM and EDS showed that the content of silver nanoparticles on the surface of PAN nanofiber was on the increase when the treating temperature rose. The bacterial reduction rates of HBP-treated PAN nanofiber against S. aureus and E. coli were about 89%, while those of the Ag/HBP/PAN nanofiber against S. aureus and E. coli were 99.9% and 99.96%, respectively, due to the cooperative effects from the amino groups in HBP and Ag nanoparticles. Moreover, the small pores and high porosity in Ag/HBP/PAN nanofiber web resulted in high filtration efficiency (99.9%) for removing smaller particles (0.1  μ m~0.7  μ m), which was much higher than that of the gauze mask.
    Type of Medium: Online Resource
    ISSN: 1687-4110 , 1687-4129
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2229480-6
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  • 3
    Online Resource
    Online Resource
    Hindawi Limited ; 2018
    In:  Mathematical Problems in Engineering Vol. 2018 ( 2018), p. 1-16
    In: Mathematical Problems in Engineering, Hindawi Limited, Vol. 2018 ( 2018), p. 1-16
    Abstract: A bidirectional B-spline QR method (BB-sQRM) for the study on the crack control of the reinforced concrete (RC) beam embedded with shape memory alloy (SMA) wires is presented. In the proposed method, the discretization is performed with a set of spline nodes in two directions of the plane model, and structural displacement fields are constructed by the linear combination of the products of cubic B-spline interpolation functions. To derive the elastoplastic stiffness equation of the RC beam, an explicit form is utilized to express the elastoplastic constitutive law of concrete materials. The proposed model is compared with the ANSYS model in several numerical examples. The results not only show that the solutions given by the BB-sQRM are very close to those given by the finite element method (FEM) but also prove the high efficiency and low computational cost of the BB-sQRM. Meanwhile, the five parameters, such as depth-span ratio, thickness of concrete cover, reinforcement ratio, prestrain, and eccentricity of SMA wires, are investigated to learn their effects on the crack control. The results show that depth-span ratio of RC beams and prestrain and eccentricity of SMA wires have a significant influence on the control performance of beam cracks.
    Type of Medium: Online Resource
    ISSN: 1024-123X , 1563-5147
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2018
    detail.hit.zdb_id: 2014442-8
    SSG: 11
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  • 4
    In: Journal of Oncology, Hindawi Limited, Vol. 2022 ( 2022-10-13), p. 1-13
    Abstract: Glioblastoma (GBM) is the most common intracranial tumor with characteristic of malignancy. Resveratrol, a natural originated polyphenolic compound, has been reported to act as a potential radiosensitizer in cancer therapy. Magnetic resonance imaging (MRI) is the first choice for the diagnosis, pathological grading, and efficacy evaluation of GBM. In this study, MRI was applied to observe whether resveratrol could intensify the anti-GBM tumor effect by enhancing antitumor immunity during radiotherapy. We established an intracranial C6 GBM model in SD rats, treated with radiation and resveratrol. The increased body weight, the inhibition on mortality, and tumor volume in radiated- GBM rats were further enhanced by resveratrol addition, while the pathological damage of brain was alleviated. The modulation of radiation on inflammation, cell cycle, and apoptosis was strengthened by resveratrol; and Ki-67, PD-L1, and cell cycle- and apoptosis-related protein expressions were also improved by cotreatment. Besides, cotreatment attenuated DNA damage and induced G0/G1-phase cell arrest of GBM rats, accompanied with the changed expression of ATM-AKT-STAT3 pathway-related proteins. Moreover, the percentages of CD3+CD8+T cells and IFN-γ+CD8+T cells were enhanced, while (CD4+CD25+Foxp3)/CD4+T cells were decreased by radiation or resveratrol, which was strengthened by cotreatment. The modulation effect of cotreatment on CD3, Foxp3, and IFN-γ levels was also stronger than radiation or resveratrol alone. To conclude, resveratrol enhanced the effect of radiotherapy by inducing DNA damage and antitumor immunity in the intracranial C6 GBM.
    Type of Medium: Online Resource
    ISSN: 1687-8469 , 1687-8450
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2461349-6
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  • 5
    In: Journal of Interventional Cardiology, Hindawi Limited, Vol. 2020 ( 2020-09-07), p. 1-7
    Abstract: Background . Nicorandil in reducing contrast-induced nephropathy (CIN) following elective percutaneous coronary intervention (PCI) is an inconsistent practice. This article aims to evaluate the efficacy and safety of nicorandil in preventing CIN after elective PCI. Methods . This is a pooled analysis of patients treated with elective PCI. The primary outcome was the incidence of CIN. The secondary outcomes were major adverse events, including mortality, heart failure, recurrent myocardial infarction, stroke, and renal replacement therapy. Results . A total of 1229 patients were recruited in our study. With statistical significance, nicorandil lowered the risk of CIN (odds ratio = 0.26; 95% confidence interval = 0.16–0.44; P 〈 0.00001 ; I 2  = 0%) in patients who underwent elective PCI. In addition, no significant differences were observed in the incidence of mortality, heart failure, recurrent myocardial infarction, stroke, and renal replacement therapy between the two groups ( P 〉 0.05 ). Conclusions . Our article indicated that nicorandil could prevent CIN without increasing the major adverse events. Furthermore, sufficiently powered and randomized clinical studies are still needed in order to determine the role of nicorandil in preventing CIN after elective PCI.
    Type of Medium: Online Resource
    ISSN: 0896-4327 , 1540-8183
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2020
    detail.hit.zdb_id: 2103585-4
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  • 6
    Online Resource
    Online Resource
    Hindawi Limited ; 2019
    In:  Mathematical Problems in Engineering Vol. 2019 ( 2019-09-25), p. 1-13
    In: Mathematical Problems in Engineering, Hindawi Limited, Vol. 2019 ( 2019-09-25), p. 1-13
    Abstract: For complex CAD models, model segmentation technology is an important support for model retrieval and reuse. In this article, we first propose a novel CAD model segmentation method that uses the fusion of the program/project evaluation and review technique (PERT) and the Laplacian spectrum theory. By means of PERT, spectral theory, and the CAD models’ geometrical and topological information, we transform the b-rep model faces into two-dimensional coordinate points corresponding to the nodes of the attributed adjacent graph (AAG). The k -means approach with the Silhouette coefficient was employed to conduct unsupervised learning of the coordinate points. The experimental results demonstrate that (1) the proposed approach can effectively transform the b-rep model into a two-dimensional coordinate point set; (2) the k -means algorithm can efficiently cluster points to achieve segmentation; and (3) in view of human cognition, the segmentation results are more reasonable. It can effectively divide the point set into several groups to achieve the model segmentation.
    Type of Medium: Online Resource
    ISSN: 1024-123X , 1563-5147
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2019
    detail.hit.zdb_id: 2014442-8
    SSG: 11
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  • 7
    In: BioMed Research International, Hindawi Limited, Vol. 2021 ( 2021-5-24), p. 1-19
    Abstract: Severe burns are acute wounds caused by local heat exposure, resulting in life-threatening systemic effects and poor survival. However, the specific molecular mechanisms remain unclear. First, we downloaded gene expression data related to severe burns from the GEO database (GSE19743, GSE37069, and GSE77791). Then, a gene expression analysis was performed to identify differentially expressed genes (DEGs) and construct protein-protein interaction (PPI) network. The molecular mechanism was identified by enrichment analysis and Gene Set Enrichment Analysis. In addition, STEM software was used to screen for genes persistently expressed during response to severe burns, and receiver operating characteristic (ROC) curve was used to identify key DEGs. A total of 2631 upregulated and 3451 downregulated DEGs were identified. PPI network analysis clustered these DEGs into 13 modules. Importantly, module genes mostly related with immune responses and metabolism. In addition, we identified genes persistently altered during the response to severe burns corresponding to survival and death status. Among the genes with high area under the ROC curve in the PPI network gene, CCL5 and LCK were identified as key DEGs, which may affect the prognosis of burn patients. Gene set variation analysis showed that the immune response was inhibited and several types of immune cells were decreased, while the metabolic response was enhanced. The results showed that persistent gene expression changes occur in response to severe burns, which may underlie chronic alterations in physiological pathways. Identifying the key altered genes may reveal potential therapeutic targets for mitigating the effects of severe burns.
    Type of Medium: Online Resource
    ISSN: 2314-6141 , 2314-6133
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2698540-8
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  • 8
    Online Resource
    Online Resource
    Hindawi Limited ; 2011
    In:  Enzyme Research Vol. 2011 ( 2011-12-29), p. 1-2
    In: Enzyme Research, Hindawi Limited, Vol. 2011 ( 2011-12-29), p. 1-2
    Type of Medium: Online Resource
    ISSN: 2090-0414
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2011
    detail.hit.zdb_id: 2573712-0
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  • 9
    Online Resource
    Online Resource
    Hindawi Limited ; 2016
    In:  Evidence-Based Complementary and Alternative Medicine Vol. 2016 ( 2016), p. 1-6
    In: Evidence-Based Complementary and Alternative Medicine, Hindawi Limited, Vol. 2016 ( 2016), p. 1-6
    Abstract: Icariin (ICA), an active component of Epimedium brevicornum Maxim, exerts a variety of neuroprotective effects such as antiapoptosis. However, the mechanisms underlying antiapoptosis of ICA in neurons exposed to oxygen-glucose deprivation and reperfusion (OGD/R) are unclear. The B-cell lymphoma-2 (Bcl-2) protein family plays an important role in the regulation of apoptosis and autophagy through Bcl-2-dependent cross talk. Bcl-2 suppresses apoptosis by binding to Bax and inhibits autophagy by binding to Beclin-1 which is an autophagy related protein. In the present study, MTT result showed that ICA increased cell viability significantly in OGD/R treated PC12 cells ( P 〈 0.01 ). Results of western blotting analysis showed that ICA increased Bcl-2 expression significantly and decreased expressions of Bax, cleaved Caspase-3, Beclin-1, and LC3-II significantly in OGD/R treated PC12 cells ( P 〈 0.01 ). These results suggest that ICA protects PC12 cells from OGD/R induced autophagy via Bcl-2-dependent cross talk between apoptosis and autophagy.
    Type of Medium: Online Resource
    ISSN: 1741-427X , 1741-4288
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2148302-4
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  • 10
    In: Evidence-Based Complementary and Alternative Medicine, Hindawi Limited, Vol. 2020 ( 2020-07-09), p. 1-8
    Abstract: Purpose . Traditional Chinese medicine (TCM) including Chinese patent medicine has been widely used to treat irritable bowel syndrome (IBS). Syndrome differentiation is the essence of TCM. However, the diagnostic ability of gastroenterologists to detect TCM syndromes in IBS in China remains unknown. The aim of this study was to investigate the ability of gastroenterologists to diagnose the TCM syndromes of IBS based on modified simple criteria compared with TCM practitioners. Methods . Patients meeting the Rome III criteria for IBS-D or IBS-C were recruited from six tertiary referral centers between January 2016 and December 2017. After learning the diagnosis criteria of the TCM syndromes in IBS, gastroenterologists first diagnosed the syndromes of the enrolled patients. Subsequently, the patients were diagnosed by TCM practitioners. The rate of agreement between the gastroenterologists and TCM practitioners was analyzed. In addition, demographic data and the distribution of TCM syndrome types in IBS were also analyzed. Results . A total of 178 patients (93 males and 85 females), including 131 patients with IBS-D and 47 patients with IBS-C, were enrolled in this study. The rate of agreement of the syndrome diagnosis between the gastroenterologists and TCM practitioners was 84.3%. The diagnosis consistency rates among IBS-D patients and IBS-C patients were 87.0% and 76.5%, respectively. The most common TCM syndrome type in IBS-D patients was liver depression and spleen deficiency syndrome (27.5%), followed by spleen-yang deficiency syndrome (19.8%). Dryness and heat in intestine syndrome was the most common TCM syndrome in IBS-C patients (57.4%). Conclusions . Gastroenterologists had good diagnostic agreement with TCM practitioners for diagnosing TCM syndrome types in IBS after learning the diagnostic criteria. This knowledge can aid gastroenterologists in selecting suitable Chinese patent medicine to treat IBS.
    Type of Medium: Online Resource
    ISSN: 1741-427X , 1741-4288
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2020
    detail.hit.zdb_id: 2148302-4
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