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  • 1
    Online Resource
    Online Resource
    Cerebral Edema Associated with Ventricular Reservoirs in Two Patients: A Case Report
    Hindawi Limited ; 2012
    In:  Case Reports in Neurological Medicine Vol. 2012 ( 2012), p. 1-5
    Details
    In: Case Reports in Neurological Medicine, Hindawi Limited, Vol. 2012 ( 2012), p. 1-5
    Abstract: Placement of ventricular reservoirs is a common practice to treat various tumors of the central nervous system (CNS). Ventricular catheter-reservoir-associated edema has been noted in the literature, but a thorough review of this literature identified no articles that examine this particular complication in neurooncology patients, specifically. We report two cases of ventricular catheter-reservoir-associated edema in patients receiving treatment for CNS metastasis.
    Type of Medium: Online Resource
    ISSN: 2090-6668 , 2090-6676
    URL: Article
    DOI: 10.1155/2012/569762
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2012
    detail.hit.zdb_id: 2629909-4
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  • 2
    Online Resource
    Online Resource
    Extraneural Metastasis of Primary Glioma Occurring in a Setting of Occupational Ionizing Radiation Exposure
    Hindawi Limited ; 2019
    In:  Case Reports in Neurological Medicine Vol. 2019 ( 2019-06-13), p. 1-6
    Details
    In: Case Reports in Neurological Medicine, Hindawi Limited, Vol. 2019 ( 2019-06-13), p. 1-6
    Abstract: Malignant gliomas account for 60% of all primary brain tumors in adults. Glioblastoma Multiforme (GBM) is the most common primary glial tumor with a dismal prognosis and a median survival of approximately 14 months. Extra-neural metastases from primary brain tumors are unusual with an incidence rate of less than 2%. This has been attributed to factors such as short survival, lack of true lymphatics in the CNS, and physical barriers provided by the dura, extracellular matrix, and basement membrane. Although most GBMs occur sporadically, there is a known association with therapeutic radiation exposure and with work in nuclear disaster cleanup. To our knowledge, no case of GBM with metastasis occurring in a patient with occupational radiation exposure currently exists in the literature. In this article, we present a case of GBM with lung metastasis occurring in a 51-year-old Caucasian male, whose history is significant for occupational exposure to ionizing radiation, and review the literature on GBM risk factors and potential mechanisms of metastasis.
    Type of Medium: Online Resource
    ISSN: 2090-6668 , 2090-6676
    URL: Article
    DOI: 10.1155/2019/1748739
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2019
    detail.hit.zdb_id: 2629909-4
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  • 3
    Online Resource
    Online Resource
    High-Grade Glioma of the Ventrolateral Medulla in an Adult: Case Presentation and Discussion of Surgical Considerations
    Hindawi Limited ; 2016
    In:  Case Reports in Neurological Medicine Vol. 2016 ( 2016), p. 1-9
    Details
    In: Case Reports in Neurological Medicine, Hindawi Limited, Vol. 2016 ( 2016), p. 1-9
    Abstract: Background . High-grade gliomas of the brainstem are rare in adults and are particularly rare in the anterolateral medulla. We describe an illustrative case and discuss the diagnostic and treatment issues associated with a tumor in this location, including differential diagnosis, anatomical considerations for options for surgical management, multimodality treatment, and prognosis. Case Description . A 69-year-old woman presented with a 3-week history of progressive right lower extremity weakness. She underwent an open biopsy via a far lateral approach with partial condylectomy, which revealed a glioblastoma. Concurrent temozolomide and radiation were completed; however, she elected to stop her chemotherapy after 5.5 weeks of treatment. She succumbed to her disease 11 months after diagnosis. Conclusions . Biopsy can be performed relatively safely to provide definitive diagnosis to guide treatment, but long-term prognosis is poor.
    Type of Medium: Online Resource
    ISSN: 2090-6668 , 2090-6676
    URL: Article
    DOI: 10.1155/2016/6813089
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2629909-4
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  • 4
    Online Resource
    Online Resource
    A Successful Treatment of Endoscopic Third Ventriculostomy with Choroid Plexus Cauterization for Hydrocephalus in Walker-Warburg Syndrome
    Hindawi Limited ; 2016
    In:  Case Reports in Neurological Medicine Vol. 2016 ( 2016), p. 1-5
    Details
    In: Case Reports in Neurological Medicine, Hindawi Limited, Vol. 2016 ( 2016), p. 1-5
    Abstract: Walker-Warburg syndrome (WWS) is a rare autosomal recessive congenital muscular dystrophy with brain malformations and ocular abnormalities that falls under the wider phenotypic spectrum of the dystroglycanopathies. Mutations in a number of genes including POMT1, POMT2, POMGNT1, POMGNT2, FKTN, FKRP, LARGE, and ISPD are known to cause alpha dystroglycan-related muscular dystrophy. Mutations in these genes result in a broad phenotypic spectrum ranging from the severe WWS to a mild congenital muscular dystrophy with no brain involvement. WWS is fatal to most patients early in life with mean survival of 9 months. The most common brain finding is cobblestone lissencephaly with the vast majority of patients (97%) also having ventricular dilation with or without hydrocephalus. Surgical treatment has not been frequently detailed. This report describes our successful treatment of a patient with WWS and hydrocephalus with Endoscopic Third Ventriculostomy (ETV) with choroid plexus cauterization (CPC). Fourteen months following treatment, a follow-up MRI CSF flow study demonstrated robust CSF flow through floor of third ventricle from interpeduncular cistern to lateral ventricle.
    Type of Medium: Online Resource
    ISSN: 2090-6668 , 2090-6676
    URL: Article
    DOI: 10.1155/2016/7627289
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2629909-4
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  • 5
    Online Resource
    Online Resource
    Hypofractionated Stereotactic Radiosurgery in a Large Bilateral Thalamic and Basal Ganglia Arteriovenous Malformation
    Hindawi Limited ; 2013
    In:  Case Reports in Neurological Medicine Vol. 2013 ( 2013), p. 1-8
    Details
    In: Case Reports in Neurological Medicine, Hindawi Limited, Vol. 2013 ( 2013), p. 1-8
    Abstract: Purpose . Arteriovenous malformations (AVMs) in the basal ganglia and thalamus have a more aggressive natural history with a higher morbidity and mortality than AVMs in other locations. Optimal treatment—complete obliteration without new neurological deficits—is often challenging. We present a patient with a large bilateral basal ganglia and thalamic AVM successfully treated with hypofractionated stereotactic radiosurgery (HFSRS) with intensity modulated radiotherapy (IMRT). Methods . The patient was treated with hypofractionated stereotactic radiosurgery to 30 Gy at margin in 5 fractions of 9 static fields with a minimultileaf collimator and intensity modulated radiotherapy. Results . At 10 months following treatment, digital subtraction angiography showed complete obliteration of the AVM. Conclusions . Large bilateral thalamic and basal ganglia AVMs can be successfully treated with complete obliteration by HFSRS with IMRT with relatively limited toxicity. Appropriate caution is recommended.
    Type of Medium: Online Resource
    ISSN: 2090-6668 , 2090-6676
    URL: Article
    DOI: 10.1155/2013/631028
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2013
    detail.hit.zdb_id: 2629909-4
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