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  • Hindawi Limited  (75)
  • 1
    Online Resource
    Online Resource
    Hindawi Limited ; 2020
    In:  Case Reports in Orthopedics Vol. 2020 ( 2020-02-07), p. 1-5
    In: Case Reports in Orthopedics, Hindawi Limited, Vol. 2020 ( 2020-02-07), p. 1-5
    Abstract: Background and Objectives. Kaposiform hemangioendothelioma (KHE) is a vascular tumor of very low incidence, which occurs mostly in children and infants. The tumor is recognized for its locally aggressive, yet rarely metastatic behavior. It may cause consumptive coagulopathy known as Kasabach-Merritt phenomenon. We report a distinctive case, where an 11-year-old boy is presented with progressive thoracolumbar scoliosis without any symptom or neurological sign. Case Report. The patient underwent spinal deformity correction via posterior pedicle screw instrumentation and fusion, along with tumor biopsy. The pathology report confirmed KHE. The patient did not show a prominent progression of scoliosis after the surgery without any further treatments. Conclusions . Many of scoliotic patients do not have any apparent cause, thereby regarded as idiopathic scoliosis. The presented case is where kaposiform hemangioendothelioma is likely to be linked to the patient’s scoliosis. We demonstrate the possibility of secondary scoliosis should always be kept in mind of orthopaedic doctors. We also conclude that secondary scoliosis does not show exacerbation after growth completion.
    Type of Medium: Online Resource
    ISSN: 2090-6749 , 2090-6757
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2020
    detail.hit.zdb_id: 2684648-2
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  • 2
    In: Journal of Nanomaterials, Hindawi Limited, Vol. 2012 ( 2012), p. 1-8
    Abstract: We report a study on manufacturing and characterization of a platform material for high-performance lightweight bipolar plates for fuel cells based on nanocomposites consisting of carbon nanotubes (CNTs) and exfoliated graphite nanoplatelets (xGnPs). The experiments were designed and performed in three steps. In the preexperimental stage, xGnP-epoxy composite samples were prepared at various xGnP weight percentages to determine the maximum processable nanofiller concentration. The main part of the experiment employed the statistics-based design of experiments (DOE) methodology to identify improved processing conditions and CNT : xGnP ratio for minimized electrical resistivity. In the postexperimental stage, optimized combinations of material and processing parameters were investigated. With the aid of a reactive diluent, 20 wt.% was determined to the be maximum processable carbon nanomaterial content in the epoxy. The DOE analyses revealed that the CNT : xGnP ratio is the most dominant factor that governs the electrical properties, and its implications in relation to CNT-xGnP interactions and microstructure are elucidated. In addition, samples fabricated near the optimized condition revealed that there exists an optimal CNT : xGnP ratio at which the electrical performance can be maximized. The electrical and mechanical properties of optimal samples suggest that CNT-xGnP hybrid nanocomposites can serve as an alternative material platform for affordable, lightweight bipolar plates.
    Type of Medium: Online Resource
    ISSN: 1687-4110 , 1687-4129
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2012
    detail.hit.zdb_id: 2229480-6
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  • 3
    In: Journal of Nanomaterials, Hindawi Limited, Vol. 2022 ( 2022-2-27), p. 1-15
    Abstract: Silver nanoparticles (AgNPs) were prepared using a pine needle extract-mediated synthesis method. The X-ray diffraction (XRD) spectrum showed a characteristic peak of silver, indicating that crystalline silver nanoparticles were formed. The synthesized AgNPs were spherical and had a uniform size of 63.9 ± 2.1   nm with a narrow size distribution. The AgNPs have been used as functional nanofillers in the manufacture of carrageenan-based functional nanocomposite films. Field emission scanning electron microscopy (FE-SEM) confirmed that AgNPs were uniformly dispersed in the carrageenan polymer matrix. The addition of AgNPs to the Carr film affected the surface color, mechanical, water vapor barrier, and surface wettability properties and significantly improved the UV blocking properties of the nanocomposite films. In addition, the carrageenan/AgNP composite films showed strong antioxidant activity and potent antibacterial activity against both Gram-positive (S. aureus) and Gram-negative (E. coli O157: H7) bacteria. The carrageenan/AgNP film with UV protection, antioxidant, and antibacterial activity can be used as active food packaging material to extend the shelf life of packaged food.
    Type of Medium: Online Resource
    ISSN: 1687-4129 , 1687-4110
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2229480-6
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  • 4
    Online Resource
    Online Resource
    Hindawi Limited ; 2016
    In:  Mathematical Problems in Engineering Vol. 2016 ( 2016), p. 1-15
    In: Mathematical Problems in Engineering, Hindawi Limited, Vol. 2016 ( 2016), p. 1-15
    Abstract: A frequency equation of externally and internally damped and shear-flexible cantilever columns subjected to a subtangentially follower force is analytically derived in a dimensionless form with relation to the linear instability theory of Beck’s columns. Some parametric studies are then performed with variation of two damping coefficients under the assumption of Rayleigh damping. Based on the analysis results, it is demonstrated that three damping cases in association with flutter loads of Beck’s columns can be selected including one case representative of structural damping. Finally, stability maps of shear-flexible and damped Beck’s columns are constructed for the three damping cases and discussed in the practical range of damping coefficients and shear parameters. In addition, flutter loads and time history analysis results are presented using dimensionless FE analysis and compared with exact solutions.
    Type of Medium: Online Resource
    ISSN: 1024-123X , 1563-5147
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2014442-8
    SSG: 11
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  • 5
    In: Canadian Journal of Gastroenterology and Hepatology, Hindawi Limited, Vol. 2016 ( 2016), p. 1-9
    Abstract: Background and Aims . Cardiac varices (CVs) in patients with type 1 gastroesophageal varices (GOV1s) usually disappear with treatment for esophageal varices (EVs) by endoscopic injection sclerotherapy (EIS). However, whether this applies to patients treated with endoscopic band ligation (EBL) for EVs remains unclear. We evaluated the effect of EVs eradication by EBL on CVs. Methods . We included cirrhotic patients whose EVs had been eradicated using EBL and excluded those who had been treated using EIS, those who had received endoscopic therapy for CVs, and those who were combined with hepatocellular carcinoma. Results . A total of 123 patients were enrolled. The age was 59.7 ± 11.7 years, and 96 patients (78.0%) were men. Thirty-eight patients (30.9%) had EVs only, while 85 (69.1%) had GOV1s. After EVs eradication, the CVs disappeared in 55 patients (64.7%). EVs recurred in 40 patients, with recurrence rates at 1, 2, and 3 years of 16.0%, 29.6%, and 35.6%, respectively, the recurrence being more frequent in patients who had undergone EBL for secondary prophylaxis and in those with persisting CVs after EVs eradication ( P = 0.003 ). Conclusions . CVs frequently disappeared when EVs were eradicated using EBL in patients with GOV1s. Persistence of CVs after EVs eradication by EBL was associated with EVs recurrence.
    Type of Medium: Online Resource
    ISSN: 2291-2789 , 2291-2797
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2762184-4
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  • 6
    In: Dermatologic Therapy, Hindawi Limited, Vol. 35, No. 9 ( 2022-09)
    Type of Medium: Online Resource
    ISSN: 1396-0296 , 1529-8019
    URL: Issue
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2020064-X
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  • 7
    In: Gastroenterology Research and Practice, Hindawi Limited, Vol. 2012 ( 2012), p. 1-4
    Abstract: Purpose . PillCam SB2 capsule endoscopy, an upgraded version of widely used SB capsule endoscopy, was examined for its performance by comparing with SB. Methods . Examinees with various indications were enrolled for SB2 capsule endoscopy; subjects were also enlisted for the old SB capsule endoscopy. Number of photo images containing papilla of Vater was counted. Shape of the papilla seen in each image was evaluated by scoring 3 (fully observable papilla), 2 (more than half outline), or 1 (less than half outline) points. Images obtained from SB and SB2 were also subjectively compared; resolution and brightness were scored by six experienced endoscopists. Results . Baseline characteristics of two study groups ( n = 30 each) were not significantly different. Number of images of the papilla revealed to show similar results between SB ( 3.1 ± 1.1 , range 1~5) and SB2 ( 3.1 ± 1.5 , range 1~8) ( P = 0.62 ). The maximum points of outline of papilla evaluated from each subject were also similar between two groups. New SB2 revealed to be superior to SB in terms of resolution but not significantly different in brightness. Conclusion . Our study showed that superiority of SB2 over SB is rather marginal on examining duodenal papilla.
    Type of Medium: Online Resource
    ISSN: 1687-6121 , 1687-630X
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2012
    detail.hit.zdb_id: 2435460-0
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  • 8
    In: Evidence-Based Complementary and Alternative Medicine, Hindawi Limited, Vol. 2014 ( 2014), p. 1-11
    Abstract: It has been previously shown that Nardostachys jatamansi (NJ) exhibits anti-inflammatory properties against lipopolysaccharide (LPS) challenges. However, the potency of NJ constituents against LPS-induced inflammatory responses has not been examined. In this present study, we determined which NJ extract fractions exhibit inhibitory effects against LPS-induced inflammatory responses. Among the NJ fractions, NJ-1, NJ-3, NJ-4, and NJ-6 inhibited LPS-induced production of NO. The NJ-3, NJ-4, and NJ-6 fractions also inhibited the production of cytokines, such as IL-1 β , IL-6, and TNF- α . However, NJ-1, NJ-3, NJ-4, and NJ-6 showed differential inhibitory mechanisms against LPS-induced inflammatory responses. NJ-1, NJ-3, and NJ-4 inhibited LPS-induced activation of c-jun NH 2 -terminal kinase (JNK) and p38 but did not affect activation of extracellular signal-regulated kinase (ERK) or NF- κ B. On the other hand, NJ-6 inhibited activation of MAPKs and NF- κ B. In addition, in vivo experiments revealed that administration of NJ-1, NJ-3, NJ-4, and NJ-6 reduced LPS-induced endotoxin shock, with NJ-6 especially showing a marked protective effect. Taken together, these results provide the evidence for the potential of selective NJ fractions against LPS-induced inflammation. Thus, it will be advantageous to further isolate and determine single effective compounds from these potent fractions.
    Type of Medium: Online Resource
    ISSN: 1741-427X , 1741-4288
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2014
    detail.hit.zdb_id: 2148302-4
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  • 9
    In: Evidence-Based Complementary and Alternative Medicine, Hindawi Limited, Vol. 2022 ( 2022-6-10), p. 1-11
    Abstract: Sargassum siliquastrum (SS) is an edible brown seaweed widely consumed in Korea and considered a functional food source. Previous studies have reported various biological activities of SS extracts, including antioxidant and hepatoprotective properties. In the present study, we examined the anti-inflammatory effects of the SS extract and assessed the underlying mechanism of action. The SS extract significantly inhibited lipopolysaccharide (LPS)-induced nitric oxide (NO) production in a dose-dependent manner (% of NO production at 500 μg/mL: 60.1 ± 0.9%), with no obvious toxicity. Furthermore, the SS extract inhibited mRNA and protein expression levels of inducible NO synthase, as well as LPS-induced expression and production of proinflammatory cytokines such as IL-1β, IL-6, or TNF-α (IL-6 production (ng/mL) : LPS−: 0.7 ± 0.3; LPS+: 68.1 ± 2.8; LPS + SS extract: 51.9 ± 1.2; TNF-α production (ng/mL) : LPS−: 0.3 ± 0.1; LPS+: 23.0 ± 0.1; LPS + SS extract: 18.2 ± 10.8). Mechanistically, the SS extract attenuated LPS-induced activation of the nuclear factor kappa-light-chain-enhancer of activated B cells (nuclear factor-kappa B, NF-κB) signaling pathway such as phosphorylation of NF-κB p65 and degradation of IκB-α, thereby blocking LPS-induced activation of NF-κB transcriptional activity. The SS extract also enhanced LPS-induced heme oxygenase-1 expression and attenuated LPS-induced cellular reactive oxygen species production (% of ROS production at 500 μg/mL: 52.2 ± 1.3%). Collectively, these findings suggest that the SS extract elicits anti-inflammatory effects in mouse macrophage cells.
    Type of Medium: Online Resource
    ISSN: 1741-4288 , 1741-427X
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2148302-4
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  • 10
    In: BioMed Research International, Hindawi Limited, Vol. 2017 ( 2017), p. 1-7
    Abstract: Purpose . To determine the association between the progression of upper lung fibrosis and paratracheal air cysts (PACs) size. Materials and Methods . The thoracic CT images of 4573 patients were reviewed for the prevalence, size, and location of PACs and their communication with trachea. In addition, the presence of upper lung fibrosis, emphysema, and bronchiectasis was evaluated in patients with PACs and compared with a control group without PACs. Upper lung fibrosis was analyzed using a fibrosis score system. Results . The prevalence of PACs was 6.8%. Communication with tracheal lumen was demonstrated by 31.5% of patients with PACs. The prevalence of fibrosis, emphysema, and bronchiectasis in patients with PACs were 67.5%, 21.9%, and 28.3%, respectively. The prevalence of fibrosis was significantly different in the two groups by univariable and multivariable analysis (odds ratio = 2.077, P 〈 0.001 ). 140 patients with fibrosis among PAC group underwent a previous or follow-up CT; the prevalence with increase in PAC sizes was higher in patients with increase in fibrosis score than those without it (66.2% versus 17.3%, P 〈 0.001 ). Conclusions . PACs appear to be highly related to upper lung fibrosis and moderately related to bronchiectasis. In patients with fibrosis, PAC sizes tended to increase with the progression of upper lung fibrosis.
    Type of Medium: Online Resource
    ISSN: 2314-6133 , 2314-6141
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2017
    detail.hit.zdb_id: 2698540-8
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