In:
Canadian Journal of Gastroenterology, Hindawi Limited, Vol. 19, No. suppl a ( 2005), p. 5A-36A
Abstract:
The discovery of a series of genetic and serological markers associated
with disease susceptibility and phenotype in inflammatory bowel disease has led to the prospect of an integrated classification system
involving clinical, serological and genetic parameters. The Working Party has reviewed current clinical classification systems in Crohn’s
disease, ulcerative colitis and indeterminate colitis, and provided recommendations for clinical classification in practice. Progress with
respect to integrating serological and genetic markers has been examined in detail, and the implications are discussed. While an integrated
system is not proposed for clinical use at present, the introduction of a widely acceptable clinical subclassification is strongly advocated,
which would allow detailed correlations among serotype, genotype and clinical phenotype to be examined and confirmed in independent
cohorts of patients and, thereby, provide a vital foundation for future work.
Type of Medium:
Online Resource
ISSN:
0835-7900
Language:
English
Publisher:
Hindawi Limited
Publication Date:
2005
detail.hit.zdb_id:
2762184-4
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