In:
Synthesis, Georg Thieme Verlag KG, Vol. 50, No. 20 ( 2018-10), p. 3997-4007
Abstract:
The diastereoselective synthesis of 1,3-diols by addition of oxygen nucleophiles to activated alkenes is presented. This review focuses on homoallylic alcohol substrates that react with a relay compound to form an intermediate oxygen nucleophile, which in turn will lead to a protected 1,3-diol by intramolecular addition to the olefin moiety. 1 Introduction 2 Base Catalysis 3 Organocatalysis 4 Activation with Non-Metallic Electrophiles 5 Activation with Transition Metal Derivatives 6 Conclusions
Type of Medium:
Online Resource
ISSN:
0039-7881
,
1437-210X
DOI:
10.1055/s-0037-1610248
Language:
English
Publisher:
Georg Thieme Verlag KG
Publication Date:
2018
detail.hit.zdb_id:
204080-3
detail.hit.zdb_id:
2033062-5
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