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  • Georg Thieme Verlag KG  (2)
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  • Georg Thieme Verlag KG  (2)
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  • 1
    Online Resource
    Online Resource
    Georg Thieme Verlag KG ; 2000
    In:  Thrombosis and Haemostasis Vol. 84, No. 11 ( 2000), p. 752-757
    In: Thrombosis and Haemostasis, Georg Thieme Verlag KG, Vol. 84, No. 11 ( 2000), p. 752-757
    Abstract: There is much debate over the appropriateness of prescribing prolonged anticoagulation to heterozygous carriers of factor V Leiden suffering a first episode of deep vein thrombosis (DVT). We, thus used meta-analysis to estimate from six eligible studies the summary odds-ratio of recurrent DVT in carriers of factor V Leiden versus noncarriers: 1.36 (CI, 1.05–1.78). After that, we used a decision model to compare lifelong costs and benefits of 6 months standard anticoagulation with those of screening for carriers of factor V Leiden and extending for 2 years their anticoagulation. Screening was a cost-effective strategy, since it provided 2 additional quality-adjusted days of life per patient at the cost of $ 12,833 per quality-adjusted year of life saved, as compared to standard management. However, screening was not costeffective in patients who were predicted to incur fatal bleeding at a rate higher than 0.34% per year or recurrent DVT at a rate lower than 9% in the first 2 years. The screening policy was cost-saving if restricted to patients with idiopathic DVT and compliant to warfarin therapy.
    Type of Medium: Online Resource
    ISSN: 0340-6245 , 2567-689X
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2000
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  • 2
    Online Resource
    Online Resource
    Georg Thieme Verlag KG ; 2017
    In:  Joints Vol. 05, No. 02 ( 2017-06), p. 085-088
    In: Joints, Georg Thieme Verlag KG, Vol. 05, No. 02 ( 2017-06), p. 085-088
    Abstract: Purpose The aim of this study was to compare the accuracy of the coracoid bone graft placement with the open Latarjet-Patte and arthroscopic Latarjet (arthro-Latarjet) procedures in the treatment of anterior instability of the shoulder. Methods Forty-six patients affected by anterior shoulder instability were divided into two groups. In group A (n = 25), patients were operated by arthroscopic Latarjet (arthro-Latarjet) procedure and in group B (n = 21), patients were operated by open Latarjet-Patte procedure. Instrumental investigation was based on three-dimensional computed tomography (3D-CT) at a minimum 1-year follow-up. Graft placement and integration, divergence and posterior protrusion of the screws, and glenohumeral osteoarthritis were considered as outcomes. Statistical analysis was performed with chi-square or Fisher's exact test. Significance was set at p  〈  0.05. Results Positioning of the coracoid graft proved to be optimal in 76% (19/25) of patients of group A and in 100% (21/21) of patients of group B (Fisher's exact test, p = 0.025). Screw placement with respect to the glenoid surface showed a posterior divergence in 44% (11/25) of patients in group A and in 24% (5/21) of patients in group B (p = 0.15). Posterior protrusion of screw was observed in 76% (19/25) of patients in group A and 71.4% (15/21) of patients in group B (p = 0.73). Graft integration was present in 76% (19/25) of patients in group A and 85.7% (18/21) of patients in group B (Fisher's exact test, p = 0.48). Mild signs of glenohumeral osteoarthritis were observed in 12% (3/25) of patients in group A and 28.6% (6/21) of patients in group B (Fisher's exact test, p = 0.26). Conclusion Patients operated with open Latarjet-Patte procedure showed better results than those of the arthro-Latarjet group in reference to the positioning of the graft on the coronal plane (p = 0.025). No significant differences between the groups were observed for graft integration, divergence of the screws, posterior protrusion of the screws, and osteoarthritis. Level of Evidence Level II, nonrandomized prospective comparative study.
    Type of Medium: Online Resource
    ISSN: 2282-4324 , 2512-9090
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2017
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