In:
Synlett, Georg Thieme Verlag KG, Vol. 31, No. 18 ( 2020-11), p. 1813-1816
Abstract:
We report a simple method for coupling of N,N-dialkyl-3-nitroarenes, elemental sulfur, and activated sp3 C–H bonds in 2-methylazaarenes or arylacetic acids to afford derivatives of 2-arylbenzothiazol-5-amines. Only DABCO base was required, and many heterocycles such as imidazoles, oxazoles, quinolines, and thiophenes were compatible with the reaction conditions. Our approach offers a simple route to useful substituted thiazol-5-amines from commercially available nitroarenes.
Type of Medium:
Online Resource
ISSN:
0936-5214
,
1437-2096
DOI:
10.1055/s-0040-1706470
Language:
English
Publisher:
Georg Thieme Verlag KG
Publication Date:
2020
detail.hit.zdb_id:
2042012-2
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