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  • Georg Thieme Verlag KG  (59)
  • 1
    Online Resource
    Online Resource
    Arthroscopic Posterior Cruciate Ligament Reconstruction: The Achilles Tendon Allograft versus the Quadriceps Tendon Allograft
    Georg Thieme Verlag KG ; 2020
    In:  The Journal of Knee Surgery Vol. 33, No. 06 ( 2020-06), p. 553-559
    Details
    In: The Journal of Knee Surgery, Georg Thieme Verlag KG, Vol. 33, No. 06 ( 2020-06), p. 553-559
    Abstract: We aimed to compare and analyze the outcomes of arthroscopic posterior cruciate ligament (PCL) reconstruction with the Achilles tendon allograft and the quadriceps tendon allograft. Twenty-nine patients who received the same procedure of arthroscopic PCL reconstruction within our inclusion criteria were reviewed retrospectively. There were 13 patients in the Achilles tendon allograft group and 16 patients in the quadriceps tendon allograft group. At least in 2 years of follow-up period, we evaluated the patients using the posterior drawer test, KT 2000 test, Lysholm knee scoring scale, Tegner activity scale score, International Knee Documentation Committee (IKDC) subjective knee form score, and Telos stress radiography. Between the two groups, no differences were found in preoperative patient demographic factors (age, gender, mean time of surgery, average follow-up period, cause of injury, and combined injury) (p  〉  0.05). Results of the posterior drawer test, KT 2000 test, Telos stress radiography, Lysholm score, Tegner activity score, and IKDC subjective score were not significantly different between the two groups at preoperative evaluation and after surgery (p  〉  0.05). On comparing preoperative evaluation and follow-up after surgery, the Achilles tendon allograft group showed significant improvement in the results of the KT 2000 test, Telos stress radiology, and Lysholm score, whereas the quadriceps tendon allograft group showed significant improvement in the results of the KT 2000 test, Telos stress radiology, Lysholm score, Tegner activity score, and IKDC subjective score (p  〈  0.05). The quadriceps tendon for arthroscopic PCL reconstruction is good alternative allograft for the Achilles tendon for arthroscopic PCL reconstruction. This is a retrospective comparative study.
    Type of Medium: Online Resource
    ISSN: 1538-8506 , 1938-2480
    URL: Article
    DOI: 10.1055/s-0039-1681029
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2020
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  • 2
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    Characteristics of Interferon-Associated Diabetes Mellitus in Past 30 Years: A Review
    Georg Thieme Verlag KG ; 2022
    In:  Hormone and Metabolic Research Vol. 54, No. 03 ( 2022-03), p. 145-152
    Details
    In: Hormone and Metabolic Research, Georg Thieme Verlag KG, Vol. 54, No. 03 ( 2022-03), p. 145-152
    Abstract: Interferon (IFN) is a broad-spectrum antiviral agent that activates cell surface receptors and causes cells to produce antiviral proteins, inhibiting viral replication. Interferon use has long been associated with diabetes. The PubMed database was searched for articles related to diabetes and interferon from March 30, 2020. Patients were divided into type 1 diabetes group and type 2 diabetes group. We reviewed the relevant literature to compare interferon-associated T1D and interferon-associated T2D differences. Interferon treatment shortened the incubation period of T2D and changed the original T2D to T1D. The onset of interferon-associated T1D required longer periods of IFN treatment than interferon-associated T2D, and the interferon-associated T1D group had higher GADA positive rates, lower BMI, lower fasting blood glucose, and greater insulin dependence (p 〈 0.05). More patients in the T1D group were positive for HLA-DRB1*04, DRB1*03, DRB1*09, DRB1*14, HLA-DQB1*04, HLA-DQB1*02, HLA-DQB1*03, and HLA-DQB1*05. The combined detection of GAD antibodies and HLA alleles may be an effective method to predict the incidence of T1D after IFN treatment.
    Type of Medium: Online Resource
    ISSN: 0018-5043 , 1439-4286
    URL: Article
    DOI: 10.1055/a-1749-5716
    RVK:
    XA 46918
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2022
    detail.hit.zdb_id: 2056576-8
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  • 3
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    Chemical Constituents Of Tribulus Terrestris L.
    Georg Thieme Verlag KG ; 2016
    In:  Planta Medica Vol. 82, No. 05 ( 2016-3-17)
    Details
    In: Planta Medica, Georg Thieme Verlag KG, Vol. 82, No. 05 ( 2016-3-17)
    Type of Medium: Online Resource
    ISSN: 0032-0943 , 1439-0221
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.1055/s-006-31317
    DOI: 10.1055/s-00000058
    DOI: 10.1055/s-0036-1578747
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2016
    detail.hit.zdb_id: 2037089-1
    SSG: 15,3
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  • 4
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    Effect of Myrtol standardized on mucus hypersecretion and clearance of Pseudomonas aeruginosa in a rat model of chronic obstructive pulmonary disease
    Georg Thieme Verlag KG ; 2012
    In:  Arzneimittelforschung Vol. 61, No. 12 ( 2012-2-9), p. 685-692
    Details
    In: Arzneimittelforschung, Georg Thieme Verlag KG, Vol. 61, No. 12 ( 2012-2-9), p. 685-692
    Type of Medium: Online Resource
    ISSN: 0004-4172 , 1616-7066
    URL: Article
    DOI: 10.1055/s-0031-1300588
    RVK:
    VA 1120
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2012
    SSG: 15,3
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  • 5
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    Transition-Metal-Catalyzed Cross-Coupling with Non-Diazo Carbene Precursors
    Georg Thieme Verlag KG ; 2019
    In:  Synlett Vol. 30, No. 05 ( 2019-03), p. 542-551
    Details
    In: Synlett, Georg Thieme Verlag KG, Vol. 30, No. 05 ( 2019-03), p. 542-551
    Abstract: Transition-metal-catalyzed cross-coupling reactions through metal carbene migratory insertion have emerged as powerful methodology for carbon–carbon bond constructions. Typically, diazo compounds (or in situ generated diazo compounds from N-tosylhydrazones) have been employed as the metal carbene precursors for this type of cross-coupling reactions. Recently, cross-coupling reactions employing non-diazo carbene precursors, such as conjugated ene-yne-ketones, allenyl ketones, alkynes, cyclopropenes, and Cr(0) Fischer carbenes, have been developed. This account will summarize our efforts in the development of transition-metal-catalyzed cross-coupling reactions with these non-diazo carbene precursors. 1 Introduction 2 Cross-Coupling with Ene-yne-ketones, Allenyl Ketones, and Alkynes 3 Cross-Coupling Involving Ring-Opening of Cyclopropenes 4 Palladium-Catalyzed Cross-Coupling with Chromium(0) Fischer Carbenes 5 Conclusion
    Type of Medium: Online Resource
    ISSN: 0936-5214 , 1437-2096
    URL: Article
    DOI: 10.1055/s-0037-1611020
    RVK:
    VA 7372
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2019
    detail.hit.zdb_id: 2042012-2
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  • 6
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    Selectfluor-Mediated Oxidative Dehydrogenation of Hydrazines: A Process for the Synthesis of Azo Compounds
    Georg Thieme Verlag KG ; 2022
    In:  Synthesis Vol. 54, No. 23 ( 2022-12), p. 5245-5252
    Details
    In: Synthesis, Georg Thieme Verlag KG, Vol. 54, No. 23 ( 2022-12), p. 5245-5252
    Abstract: A facile method to synthesize azo compounds from hydrazine derivatives is developed. This represents the unprecedented example of Selectfluor-mediated oxidative dehydrogenation of hydrazine derivatives. The reaction might proceed through N-fluorination and elimination processes. This protocol exhibits key features including simple operation, mild conditions, good functional group tolerance, and high efficiency. Moreover, the advantage is also highlighted by the conversion of a sulfonyl-substituted azo compound to furnish acetanilide in excellent yield under 4 W blue LED irradiation.
    Type of Medium: Online Resource
    ISSN: 0039-7881 , 1437-210X
    URL: Article
    DOI: 10.1055/a-1899-5563
    RVK:
    VA 7380
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2022
    detail.hit.zdb_id: 204080-3
    detail.hit.zdb_id: 2033062-5
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  • 7
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    Stroke prevention in atrial fibrillation: An Asian perspective
    Georg Thieme Verlag KG ; 2014
    In:  Thrombosis and Haemostasis Vol. 112, No. 05 ( 2014), p. 789-797
    Details
    In: Thrombosis and Haemostasis, Georg Thieme Verlag KG, Vol. 112, No. 05 ( 2014), p. 789-797
    Abstract: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. In 2050, it is estimated that there will be 72 million AF patients in Asia, accounting for almost 2.9 million patients suffering from AF-associated stroke. Asian AF patients share similar risk factor profiles as non-Asians, except that more Asians have a history of previous stroke. Clinical challenges are evident in the field of stroke prevention in AF, amongst Asians. Existing stroke and bleeding risk scores have not been well-validated in Asians. Asians are prone to bleeding when treated with warfarin, and the optimal international normalised ratio (INR) for warfarin use is yet to be determined in Asians, though Asian physicians tend to keep it in a lower range (e.g. INR 1.6–2.6) for elderly patients despite limited evidence to justify this. In general, warfarin is ‘difficult’ to use in Asians due to higher risk of bleeding and higher stroke rate in Asians than in non-Asians, as shown in randomised controlled trials. Excess of bleeding was not found in Asians when novel oral anticoagulants (NOACs) were used. Besides, the superiority of NOACs to warfarin in reducing thromboembolism was maintained in Asians. Therefore NOACs are preferentially indicated in Asians in terms of both efficacy and safety. Also, some preliminary data suggest that Asian patients with AF might not be the same. Future prospective randomised trials are needed for the selection of NOACs according to different ethnic background. Note: The review process for this manuscript was fully handled by Christian Weber, Editor in Chief.
    Type of Medium: Online Resource
    ISSN: 0340-6245 , 2567-689X
    URL: Article
    DOI: 10.1160/TH13-11-0948
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2014
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  • 8
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    Comparison of Different Concentrations of Ropivacaine Used for Ultrasound-Guided Adductor Canal Block + IPACK Block in Total Knee Arthroplasty
    Georg Thieme Verlag KG ; 2023
    In:  The Journal of Knee Surgery Vol. 36, No. 12 ( 2023-10), p. 1273-1282
    Details
    In: The Journal of Knee Surgery, Georg Thieme Verlag KG, Vol. 36, No. 12 ( 2023-10), p. 1273-1282
    Abstract: This study aimed to compare the analgesic efficacy of different concentrations of ropivacaine used for the combination of ultrasound-guided adductor canal block (ACB) and infiltration between the popliteal artery and capsule of the posterior knee (IPACK) block in total knee arthroplasty (TKA). Before general anesthesia, 90 patients undergoing TKA were randomized to receive ACB + IPACK block with ropivacaine 0.2, 0.25, or 0.3% (defined as group A, B, and C, respectively). Primary outcome was the reported visual analog scale (VAS) pain scores at rest 30 minutes following arrival to the postanesthesia care unit (PACU). Secondary outcomes were postoperative VAS pain scores, postoperative morphine consumption, the time to first rescue analgesia, functional recovery of knee (including the range of motion and quadriceps strength), and postoperative complications. Compared with group A, group B and group C had significantly lower VAS scores 30 minutes following arrival to the PACU (p  〈  0.001 and p  〈  0.001, respectively). These two groups also had significantly lower VAS pain scores at postoperative 2 hours (at rest: p = 0.037 and 0.002; during motion: p = 0.035 and 0.001, respectively) and 6 hour (at rest: p = 0.033 and 0.002; during motion: p  〈  0.001 and p  〈  0.001, respectively), lower postoperative morphine consumption (p = 0.001 and 0.002, respectively), longer time to first rescue analgesia (p = 0.010 and 0.009, respectively), and better range of knee motion on the day of surgery (p = 0.008 and 0.002, respectively). Group B and group C showed no significant differences in these outcomes between each other (p  〉  0.05). The three groups did not show a significant difference in postoperative quadriceps strength and complication rates (p  〉  0.05). Compared with ropivacaine 0.2%, ropivacaine 0.25 and 0.3% can provide early pain relief in the first 6 hours after surgery. Ropivacaine 0.25 and 0.3% may provide more clinical benefits for patients undergoing outpatient TKA.
    Type of Medium: Online Resource
    ISSN: 1538-8506 , 1938-2480
    URL: Article
    DOI: 10.1055/s-0042-1755368
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2023
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  • 9
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    Different Doses of Intravenous Tranexamic Acid in Revision Total Knee Arthroplasty: A Retrospective Study
    Georg Thieme Verlag KG ; 2023
    In:  The Journal of Knee Surgery Vol. 36, No. 06 ( 2023-05), p. 652-657
    Details
    In: The Journal of Knee Surgery, Georg Thieme Verlag KG, Vol. 36, No. 06 ( 2023-05), p. 652-657
    Abstract: Purpose This article assessed the efficacy and safety of different doses of intravenous tranexamic acid (TXA) in revision total knee arthroplasty (TKA). Methods We retrospectively identified 122 patients in our institution who underwent revision TKA with a history of perioperative intravenous TXA utilization. According to the sum of intravenous TXA documented, all patients were divided into three groups: 1 g intravenous TXA, 2 g intravenous TXA, and equal or greater than 3 g intravenous TXA. The primary outcomes included total blood loss (TBL), hidden blood loss (HBL), transfusion rate, and the incidence of symptomatic venous thromboembolism among the three groups. A correlation analysis was conducted to analyze the correlation between the dose of TXA and the blood loss. Results In total, there was no significance difference in TBL and revised HBL (rHBL) between the first two groups (1 g/dL for intravenous TXA, 2 g/dL for intravenous TXA; p = 0.486; p = 0.525). Equal or greater than 3 g intravenous TXA (≥3 g/dL for intravenous TXA) reached a significant reduction in TBL, rHBL, and length of stay compared with the first two groups (p = 0.01; p = 0.01; p = 0.01). The rate of transfusion between the three groups did not differ significantly (p = 0.21). Due to the limitations in sample size, only one symptomatic venous thromboembolism was reported in the 1 g intravenous TXA group. Conclusion Applying the dose of intravenous TXA equal or greater than 3 g in revision TKA might further reduce the blood loss and shorten the length of stay.
    Type of Medium: Online Resource
    ISSN: 1538-8506 , 1938-2480
    URL: Article
    DOI: 10.1055/s-0041-1740585
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2023
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  • 10
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    A Supercritical Fluid Based Approach to Sample Work-up, Analysis and Purification in Natural Product Research
    Georg Thieme Verlag KG ; 2012
    In:  Planta Medica Vol. 78, No. 05 ( 2012-4)
    Details
    In: Planta Medica, Georg Thieme Verlag KG, Vol. 78, No. 05 ( 2012-4)
    Type of Medium: Online Resource
    ISSN: 0032-0943 , 1439-0221
    URL: Article
    DOI: 10.1055/s-0032-1307507
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2012
    detail.hit.zdb_id: 2037089-1
    SSG: 15,3
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