In:
Pain Management, Future Medicine Ltd, Vol. 8, No. 5 ( 2018-09-01), p. 353-361
Abstract:
Aim: To summarize the literature on the long-term impact of perioperative opioids in colorectal cancer. Materials & methods: Combined results from two searching strategies in PubMed/MEDLINE (1950–2018), based on a PICO approach; P: Opioid influence on cancer-related long-term outcome in patient undergoing colorectal surgery; I: Opioid drugs administered in the perioperative period; C: Correlation between dose and/or type of opioid with long-term oncologic outcome; O: Disease-free survival and/or overall survival (OS). Results: Thirteen articles fulfilled the predetermined inclusion criteria. Due to the heterogeneity of the different studies, a quantitative meta-analysis to sum the evidence was deemed unfeasible. Conclusion: Our review indicates that there is no conclusive evidence to avoid the use of opioids with the goal of reducing the risk of recurrence in colorectal cancer.
Type of Medium:
Online Resource
ISSN:
1758-1869
,
1758-1877
DOI:
10.2217/pmt-2018-0029
Language:
English
Publisher:
Future Medicine Ltd
Publication Date:
2018
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