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  • 1
    In: Frontiers in Veterinary Science, Frontiers Media SA, Vol. 8 ( 2021-11-17)
    Abstract: A large variety of clinical manifestation in individual pigs occurs after infection with pathogens involved in porcine respiratory disease complex (PRDC). Some pigs are less prone to develop respiratory disease symptoms. The variation in clinical impact after infection and the recovery capacity of an individual animal are measures of its resilience. In this paper, we examined which ones of a range of animal-based factors (rectal temperature, body weight, skin lesion scores, behavior, natural antibody serum levels, serum levels of white blood cells, and type of T and granulocyte subsets) when measured prior to infection are related to disease severity. These animal-based factors and the interaction with housing regimen of the piglets (conventional or enriched) were modeled using linear regression to predict disease severity using a dataset acquired from a previous study using a well-established experimental coinfection model of porcine reproductive and respiratory syndrome virus (PRRSV) and Actinobacillus pleuropneumoniae . Both PRRSV and A. pleuropneumoniae are often involved in PRDC. Histological lung lesion score of each animal was used as a measure for PRDC severity after infection. Prior to infection, higher serum levels of lymphocytes (CD3 + ), naïve T helper (CD3 + CD4 + CD8 − ), CD8 + (as well as higher relative levels of CD8 + ), and memory T helper (CD3 + CD4 + CD8 + ) cells and higher relative levels of granulocytes (CD172 a ) were related to reduced disease severity in both housing systems. Raised serum concentrations of natural IgM antibodies binding to keyhole limpet hemocyanin (KLH) were also related to reduced disease severity after infection. Increased levels of skin lesions at the central body part (after weaning and before infection) were related to increased disease severity in conventional housing systems only. High resisters showed a lower histological lung lesion score, which appeared unrelated to sex. Body temperature, behavior, and growth prior to infections were influenced by housing regimen but could not explain the variation in lung lesion scores after infection. Raised basal lymphocyte counts and lower skin lesion scores are related to reduced disease severity independent of or dependent on housing system, respectively. In conclusion, our study identifies intrinsic animal-based measures using linear regression analysis that predicts resilience to infections in pigs.
    Type of Medium: Online Resource
    ISSN: 2297-1769
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2834243-4
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  • 2
    Online Resource
    Online Resource
    Frontiers Media SA ; 2022
    In:  Frontiers in Psychology Vol. 13 ( 2022-6-2)
    In: Frontiers in Psychology, Frontiers Media SA, Vol. 13 ( 2022-6-2)
    Abstract: Like any other career process, career changes are influenced by relationships. Moreover, involuntary career changes are a challenging, yet understudied, career transition. Based on a relational perspective of work and careers, we investigated the way people’s social environment affects the process and experience of involuntary career changes. Specifically, we aimed to identify the sources of relational influences and to understand how these influences affect career changes. Semi-structured interviews were carried out with 14 adults who were forced to change career because of unemployment or health issues. Through thematic analysis, we identified three sources of relational influences (personal, work, and institutional environment) and three forms of influence that others had on career changes (positive, negative, and ambivalent). These influences manifested at four distinct moments of the process: When participants were leaving their former job, when they were shifting between their former occupation and a new livelihood, when they were exploring new career options, or when they were trying to implement their new career plan. Overall, results suggest that involuntary career changes are deeply shaped by heterogeneous and differentiated relational influences. The effect of the personal environment varied depending on the moment of the career change process. In particular, family and friends tended to be perceived as barriers when it came to shifting from the old to a new occupation and implementing a new career plan. The work environment mostly had a negative effect on the career change experience, suggesting the labor market might be somewhat refractory toward adult career changers. Institutions played a critical role throughout the change process, with support structures often being perceived as inappropriate, but with guidance professionals generally recognizing participants’ difficulties. Moreover, diverse forms of ambivalence characterized the identified relational influences, which were sometimes both appreciated and avoided or had ambiguous and fluctuating effects. Finally, although being a fundamentally social experience, involuntary career changes were also characterized by moments of loneliness that reflected the inadequacy of available support and a sense of shame associated with the status of career changer. Study limitations, research perspectives, and practical implications at the labor market, institutional, and individual levels are addressed.
    Type of Medium: Online Resource
    ISSN: 1664-1078
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2563826-9
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  • 3
    In: Frontiers in Marine Science, Frontiers Media SA, Vol. 6 ( 2019-10-15)
    Type of Medium: Online Resource
    ISSN: 2296-7745
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2019
    detail.hit.zdb_id: 2757748-X
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  • 4
    In: Frontiers in Earth Science, Frontiers Media SA, Vol. 11 ( 2023-3-16)
    Abstract: Ionospheric disturbances (such as electromagnetic emissions) in connection to strong earthquakes have been reported in literature for over two decades. In order to be reliable, the identification of such disturbances requires a preliminary robust definition of the ionospheric background in the absence of both seismic activity and any other possible input (e.g., transient change in solar activity). In this work, we present a new technique for the assessment of the electromagnetic (EM) background in the ionosphere over seismic regions. The background is estimated via a multiscale statistical analysis that makes use of most of the electric- and magnetic-field datasets (2019–2021) from the China Seismo-Electromagnetic Satellite (CSES-01). The result is a map of the average relative energy in a 6° x 6° LAT-LON cell centered at the earthquake epicenter (EE). Only EM signals that statistically differ from the background should be considered as events suitable for investigation. The method is tested against two strong seismic events, the 14 August 2021 Haitian earthquake (7.2 M W ) and the 27 September 2021 Cretan earthquake (6.0 M W ). In the former case, a signal (with characteristic frequency of 250 Hz) can be identified, which emerges from the background. In the latter one, the concurrent strong geomagnetic activity does not allow to tell any distinct signal apart from the background.
    Type of Medium: Online Resource
    ISSN: 2296-6463
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 2741235-0
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