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  • 1
    Publication Date: 2022-05-25
    Description: Author Posting. © IEEE, 2004. This article is posted here by permission of IEEE for personal use, not for redistribution. The definitive version was published in IEEE Journal of Oceanic Engineering 29 (2004): 1264-1279, doi:10.1109/JOE.2004.836997.
    Description: We present analyses of fluctuations seen in acoustic signals transmitted by two 400-Hz sources moored as part of the ASIAEX 2001 South China Sea (SCS) experiment. One source was near the bottom in 350-m deep water 31.3 km offshore from the receiving array, and the other was near the bottom in 135-m deep water 20.6 km alongshore from the array. Time series of signal intensity measured at individual phones of a 16-element vertical line array are analyzed, as well as time series of intensity averaged over the array. Signals were recorded from 2 May to 17 May 2001. Fluctuations were observed at periods ranging from subtidal (days) to the shortest periods resolved with our signaling (10 s). Short-period fluctuations of depth- and time-averaged intensity have scintillation indexes (computed within 3-h long windows) which peak at values near 0.5 during an interval of numerous high-amplitude internal gravity waves, and which are lower during intervals with fewer internal waves. The decorrelation times of the averaged intensity (energy level) are also closely related to internal wave properties. Scintillation indexes computed for unaveraged pulses arriving at individual phones often exceed unity.
    Description: This work was supported by the U.S. Office of Naval Research.
    Keywords: Acoustic intensity ; Fluctuation ; Underwater acoustic propagation
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: 1070723 bytes
    Format: application/pdf
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  • 2
    Publication Date: 2022-10-26
    Description: © The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Centurioni, L. R., Turton, J., Lumpkin, R., Braasch, L., Brassington, G., Chao, Y., Charpentier, E., Chen, Z., Corlett, G., Dohan, K., Donlon, C., Gallage, C., Hormann, V., Ignatov, A., Ingleby, B., Jensen, R., Kelly-Gerreyn, B. A., Koszalka, I. M., Lin, X., Lindstrom, E., Maximenko, N., Merchant, C. J., Minnett, P., O'Carroll, A., Paluszkiewicz, T., Poli, P., Poulain, P., Reverdin, G., Sun, X., Swail, V., Thurston, S., Wu, L., Yu, L., Wang, B., & Zhang, D. Global in situ observations of essential climate and ocean variables at the air-sea interface. Frontiers in Marine Science, 6, (2019): 419, doi: 10.3389/fmars.2019.00419.
    Description: The air–sea interface is a key gateway in the Earth system. It is where the atmosphere sets the ocean in motion, climate/weather-relevant air–sea processes occur, and pollutants (i.e., plastic, anthropogenic carbon dioxide, radioactive/chemical waste) enter the sea. Hence, accurate estimates and forecasts of physical and biogeochemical processes at this interface are critical for sustainable blue economy planning, growth, and disaster mitigation. Such estimates and forecasts rely on accurate and integrated in situ and satellite surface observations. High-impact uses of ocean surface observations of essential ocean/climate variables (EOVs/ECVs) include (1) assimilation into/validation of weather, ocean, and climate forecast models to improve their skill, impact, and value; (2) ocean physics studies (i.e., heat, momentum, freshwater, and biogeochemical air–sea fluxes) to further our understanding and parameterization of air–sea processes; and (3) calibration and validation of satellite ocean products (i.e., currents, temperature, salinity, sea level, ocean color, wind, and waves). We review strengths and limitations, impacts, and sustainability of in situ ocean surface observations of several ECVs and EOVs. We draw a 10-year vision of the global ocean surface observing network for improved synergy and integration with other observing systems (e.g., satellites), for modeling/forecast efforts, and for a better ocean observing governance. The context is both the applications listed above and the guidelines of frameworks such as the Global Ocean Observing System (GOOS) and Global Climate Observing System (GCOS) (both co-sponsored by the Intergovernmental Oceanographic Commission of UNESCO, IOC–UNESCO; the World Meteorological Organization, WMO; the United Nations Environment Programme, UNEP; and the International Science Council, ISC). Networks of multiparametric platforms, such as the global drifter array, offer opportunities for new and improved in situ observations. Advances in sensor technology (e.g., low-cost wave sensors), high-throughput communications, evolving cyberinfrastructures, and data information systems with potential to improve the scope, efficiency, integration, and sustainability of the ocean surface observing system are explored.
    Description: LC, LB, and VH were supported by NOAA grant NA15OAR4320071 and ONR grant N00014-17-1-2517. RL was supported by NOAA/AOML and NOAA’s Ocean Observation and Monitoring Division. NM was partly supported by NASA grant NNX17AH43G. IK was supported by the Nordic Seas Eddy Exchanges (NorSEE) funded by the Norwegian Research Council (Grant 221780). DZ was partly funded by the Joint Institute for the Study of the Atmosphere and Ocean (JISAO) under NOAA Cooperative Agreement NA15OAR4320063. RJ was supported by the USACE’s Civil Works 096×3123.
    Keywords: Global in situ observations ; Air-sea interface ; Essential climate and ocean variables ; Climate variability and change ; Weather forecasting ; SVP drifters
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 3
    Publication Date: 2012-06-10
    Description: Hepatic progenitor cells (HPC) play important roles in both liver regeneration and carcinogenesis. Combined hepatocellular-cholangiocarcinoma (CHC), a malignant primary liver tumor with poor prognosis, is thought to be of HPC origin. However, the prognostic significance of this etiology is not well defined. Therefore, we retrospectively investigated the relationship of HPC-related pathological features and long-term outcome in patients with CHC in our department. In a cohort of 80 patients identified between 1997 and 2003, including 70 patients who underwent resection with curative intent, overall survival (OS) and disease-free survival (DFS) were correlated with the proliferative activity of non-tumor ductular reaction (DR) and the expression levels of HPC and biliary markers including α-fetoprotein (AFP), Keratin 7 (K7), Keratin 19 (K19), oval cell (OV)-6, epithelial cell adhesion molecule (EpCAM) and c-Kit in both tumor and non-tumor liver. We found that non-tumor ductular reactions (DRs), specifically the proliferating cell nuclear antigen (PCNA) labeling index of the ductular reaction (PI-DR), a surrogate for transit-amplifying compartments, was an independent prognostic factor for both OS and DFS. By contrast, intratumoral expression of only one marker, absence of AFP, was associated with OS. PI-DR was also found independently associated with synchronous “multicentric occurrence” in hepatocellular carcinoma components, a feature of CHC may predispose to metachronous multifocal tumorigenesis. Conclusion: Proliferative ductular reaction related to HPC activation is associated with recurrence of CHC. Background HPC activation is strongly associated with multifocal occurrence and related tumor recurrence, highlighting the critical role of background liver disease, a “field effect”, in the recurrence of CHC. (H EPATOLOGY 2012.)
    Print ISSN: 0270-9139
    Electronic ISSN: 1527-3350
    Topics: Medicine
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