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  • 1
    In: Biota Neotropica, FapUNIFESP (SciELO), Vol. 2, No. 2 ( 2002), p. 1-18
    Abstract: Based on population data provided by the 2000 IBGE census, the volume of domestic sewage, the volume of treated sewage, the potential and remnant domestic sewage loads and the equivalent carbon and nitrogen loads were estimated for each one of the 645 counties of the São Paulo State and for the catchments of the rivers Piracicaba, Mogi-Guaçu, Turvo, Peixe, Aguapeí, São José dos Dourados, Itapetininga, Apiaí, Taquari, and Paranapanema. In order to estimate these parameters the existence of sewage collecting system, and the existence of any kind of sewage treatment in each county of the State were taken into account. The database generated in this study may be found at www.cena.usp.br/biota. Despite of the historical attempts of the São Paulo State government in treating sewage, only 17% of the sewage volume produced in the State has some type of treatment before it is launched to rivers. Consequently, the load of untreated sewage is indeed very large. This input of extra organic matter causes severe alterations in water bodies. Among the catchments we have analyzed the Piracicaba River basin is the most affected by domestic sewage, followed by Mogi-Guaçu and Turvo basins. On the other hand, the basins of the rivers Itapeteninga, Apiaí, Taquari and Paranapanema are the least affected.
    Type of Medium: Online Resource
    ISSN: 1676-0611 , 1806-129X
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2002
    detail.hit.zdb_id: 2145494-2
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  • 2
    In: Revista de Saúde Pública, FapUNIFESP (SciELO), Vol. 46, No. 4 ( 2012-08), p. 617-623
    Type of Medium: Online Resource
    ISSN: 0034-8910
    Language: English
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2012
    detail.hit.zdb_id: 2031055-9
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  • 3
    Online Resource
    Online Resource
    FapUNIFESP (SciELO) ; 2012
    In:  Anais Brasileiros de Dermatologia Vol. 87, No. 1 ( 2012-02), p. 45-51
    In: Anais Brasileiros de Dermatologia, FapUNIFESP (SciELO), Vol. 87, No. 1 ( 2012-02), p. 45-51
    Abstract: FUNDAMENTOS: A biomembrana vegetal tem sido usada para tratamento de úlceras cutâneas. OBJETIVOS: Avaliar a ação da biomembrana vegetal no tratamento de úlceras venosas crônicas, comparando-a ao tratamento à base de colagenase. MÉTODOS: Foram selecionados 14 pacientes tratados com biomembrana vegetal e sete com Fibrase® (grupo controle), acompanhados clínico-fotograficamente pelo índice de cicatrização das úlceras (ICU) por 120 dias, por meio do software ImageJ, e biopsiados no primeiro e 30º dias para estudo histopatológico. RESULTADOS: A biomembrana vegetal foi superior em relação ao controle na cicatrização das úlceras no 30º dia, especialmente na fase inflamatória, confirmada pela exsudação abundante e pelo desbridamento. Houve tendência superior à angiogênese seguida de reepitelização com maiores ICUs no 90º e 120º dias. CONCLUSÃO: A análise conjunta dos achados clínicos e histopatológicos sugere que a biomembrana vegetal atuou como um fator indutor da cicatrização, especialmente na fase inflamatória, confirmada pela exsudação abundante das lesões, promovendo a transformação do microambiente das úlceras venosas crônicas e estimulando a angiogênese e a posterior reepitelização.
    Type of Medium: Online Resource
    ISSN: 0365-0596
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2012
    detail.hit.zdb_id: 2145422-X
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  • 4
    In: Anais Brasileiros de Dermatologia, FapUNIFESP (SciELO), Vol. 89, No. 6 ( 2014-12), p. 899-904
    Type of Medium: Online Resource
    ISSN: 0365-0596
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2014
    detail.hit.zdb_id: 2145422-X
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  • 5
    Online Resource
    Online Resource
    FapUNIFESP (SciELO) ; 2011
    In:  Anais Brasileiros de Dermatologia Vol. 86, No. 5 ( 2011-10), p. 885-891
    In: Anais Brasileiros de Dermatologia, FapUNIFESP (SciELO), Vol. 86, No. 5 ( 2011-10), p. 885-891
    Abstract: BACKGROUND: The natural biomembrane of latex extracted from Hevea brasiliensis has been used as a dressing for skin ulcers. OBJECTIVES: To evaluate how safe the natural biomembrane is in relation to hypersensitivity to latex when used as a dressing. METHODS: We selected patients with skin ulcers, forming the following groups: control - low occupational exposure to latex (n = 17); latex-exposed control - high occupational exposure (n = 14); ulcerated, using the natural biomembrane (n = 13); ulcerated control, not using the natural biomembrane (n = 14); and new cases (n = 9), assessed before and after 3 months of using the natural biomembrane. All patients underwent clinical and epidemiological evaluation for latex hypersensitivity and specific IgE (UniCap®), and the control and latex-exposed control groups underwent the patch test. RESULTS: Hypersensitivity was positive in 64.7% of the patients in the control group, 71.4% of the patients in the latex-exposed control group, 61.5% of the ulcerated using the natural biomembrane, 35.7% of the ulcerated control, and only 22 , 2% of the new cases. In the patch test of the control and latex-exposed control groups, only one individual in the control group (low contact) showed erythema in the first reading, which became negative in the second. The mean contact with latex in the latex-exposed control group was 3.42 hours / day. In the fluoroimmunoenzymatic assay, most of the sera was classified as zero (range 0-6). No serum was rated above 2, which is not considered significant for hypersensitivity (classification 〉 4). CONCLUSION: The natural biomembrane proved to be safe as a dressing, for it did not induce hypersensitivity reactions among the volunteers who underwent the patch test or among users of the natural biomembrane, as it was clinically and immunologically demonstrated by IgE levels.
    Type of Medium: Online Resource
    ISSN: 0365-0596
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2011
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  • 6
    In: Revista de Saúde Pública, FapUNIFESP (SciELO), Vol. 46, No. 4 ( 2012-08), p. 617-623
    Abstract: OBJECTIVE: To assess the association between depression and chronic diseases in adults. METHODS: Population-based cross-sectional study with a sample of 1,720 adults aged 20 to 59 years conducted in the city of Florianópolis, southern Brazil, in 2009. Multistage sampling was used and census tracts were the primary sample unit. Subjects were interviewed at home, and reported being diagnosed with depression (outcome) and 11 other chronic diseases (exploratory variable) by a health provider. They were grouped into those with no chronic disease, one, and two or more diseases. Gender, age, marital status, income, physical activity, hospitalization and medical visits were confounders. Poisson regression analysis was used to estimate prevalence ratios and related 95% confidence intervals. RESULTS: The prevalence os depression was 16.2% (95%CI 14.3;18.2). It was higher in women, older individuals, widowed or divorced, and poor ones. Those who reported no leisure-time physical activity and medical visits in the last two weeks, and who were hospitalized in the last year also showed higher prevalence of depression and chronic diseases. Even after adjustment for confounders the prevalence of depression was 1.44 (95%CI 1.09;1.92) times higher among those reporting one chronic disease and 2.25 times higher among those reporting two or more diseases than among those with no diseases. CONCLUSIONS: The prevalence of depression is much higher among people with higher burden of chronic diseases. Health professionals, health services, and policy makers must target specific strategies to this group.
    Type of Medium: Online Resource
    ISSN: 0034-8910
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2012
    detail.hit.zdb_id: 2031055-9
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  • 7
    In: Anais Brasileiros de Dermatologia, FapUNIFESP (SciELO), Vol. 90, No. 3 ( 2015-06), p. 347-350
    Type of Medium: Online Resource
    ISSN: 0365-0596
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2015
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  • 8
    Online Resource
    Online Resource
    FapUNIFESP (SciELO) ; 2011
    In:  Anais Brasileiros de Dermatologia Vol. 86, No. 4 ( 2011-08), p. 681-688
    In: Anais Brasileiros de Dermatologia, FapUNIFESP (SciELO), Vol. 86, No. 4 ( 2011-08), p. 681-688
    Abstract: BACKGROUND: The skin requires adequate levels of nutrients to function properly. OBJECTIVE: To analyze skin trophism in well-nourished and undernourished rats using two models of malnutrition. METHODS: In the marasmus model, 60 Wistar rats were kept on a controlled diet, 30 being randomly selected to receive half the established diet for 60 days. In the gelatin model, 60 rats were used, 30 of which received a diet consisting of poor quality protein (gelatin) for 30 days. The nutritional status of the animals was evaluated according to body mass index, clinical signs and serum albumin measurement. After the period of malnutrition, histology was performed on the animals' skin to analyze the thickness of the dermis and epidermis using the Leica Application Suite software. Collagen was analyzed on slides stained with Gömöri trichrome using the ImageJ software program. RESULTS: The body mass index of the malnourished animals in the marasmus and gelatin groups was significantly lower than that of the well-nourished animals in the two groups (p 〈 0.0001 in both models). With respect to serum albumin, there was no difference between the groups in either of the two models. In relation to the histological analysis of skin thickness, the dermis of the malnourished animals was significantly thinner compared to that of the well-nourished animals (p 〈 0.0001 in both models). The percentage of collagen was lower in the malnourished animals compared to the well-nourished animals (p 〈 0.0005 and p 〈 0.003 in the marasmus and gelatin model, respectively). CONCLUSIONS: Skin thickness measurements were lower in the malnourished animals in both models, and this finding was histologically confirmed by the lower percentage of collagen, showing the negative effect of malnutrition on skin trophism
    Type of Medium: Online Resource
    ISSN: 0365-0596
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2011
    detail.hit.zdb_id: 2145422-X
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  • 9
    In: Revista de Saúde Pública, FapUNIFESP (SciELO), Vol. 46, No. 2 ( 2012-04), p. 359-366
    Abstract: OBJETIVO: Describir la tendencia de hospitalizaciones por condiciones susceptibles a atención primaria entre 1998 y 2009 en Brasil. MÉTODOS: Estudio ecológico de series temporales con datos secundarios relacionados con las Internaciones Hospitalarias por condiciones susceptibles a atención primaria en el Sistema Único de Salud de Brasil. Los datos fueron obtenidos del Sistema de Informaciones Hospitalarias. Las tasas de internaciones por 10.000 habitantes fueron estandarizadas por grupo etario y sexo, considerando la población brasileña masculina recensada en 2000 como patrón. El análisis de tendencia de la serie histórica fue realizado por regresión linear generalizado por el método de Prais-Winsten. RESULTADOS: Hubo reducción en el promedio anual de internaciones por condiciones susceptibles a atención primaria de 3,7% entre hombres (IC95% -2,3;-5,1) y mujeres (IC95% -2,5;-5,6) entre 1998 y 2009. La tendencia varió en cada unidad federativa, sin embargo, en ninguna hubo aumento de las internaciones. En el sexo masculino y femenino las mayores reducciones fueron observadas en las internaciones por úlceras gastrointestinales (-11,7% al año y -12,1%, respectivamente), condiciones evitables (-8,8% y -8,9%) y enfermedades de las vías aéreas inferiores (-8,0% y -8,1%). Angina (hombres), infección en el riñón y tracto urinario (hombres y mujeres) y condiciones relacionados al prenatal y parto (mujeres) presentaron aumento en las internaciones. Los tres grupos de enfermedades que más ocasionaron internaciones fueron gastroenteritis infecciosas y complicaciones, internaciones por insuficiencia cardíaca y asma. CONCLUSIONES: Hubo reducción sustancial en las internaciones por condiciones susceptibles a atención primaria en Brasil entre 1998 y 2009, sin embargo, algunas enfermedades presentaron estabilidad o aumento, exigiendo atención del sector salud.
    Type of Medium: Online Resource
    ISSN: 0034-8910
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2012
    detail.hit.zdb_id: 2031055-9
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