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  • 1
    In: Endoskopi Gastrointestinal, Endoscopy Gastrointestinal
    Type of Medium: Online Resource
    ISSN: 1302-5422
    Language: Turkish
    Publisher: Endoscopy Gastrointestinal
    Publication Date: 2016
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  • 2
    In: Endoskopi Gastrointestinal, Endoscopy Gastrointestinal
    Type of Medium: Online Resource
    ISSN: 1302-5422
    Language: Turkish
    Publisher: Endoscopy Gastrointestinal
    Publication Date: 2017
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  • 3
    In: Endoskopi Gastrointestinal, Endoscopy Gastrointestinal, Vol. 26, No. 1 ( 2018-04-26), p. 12-16
    Abstract: Background and Aims: Serious complications have been reported with endoscopic retrograde cholangiopancreatography, a widely used method for the diagnosis and treatment of bile duct and pancreatic diseases. These complications include hemorrhage from the sphincterotomy site due to the endoscopic retrograde cholangiopancreatography procedure; pancreatitis; cholangitis; cardiopulmonary complications such as perforation, hypoxia, and hypotension, arrhythmia; and death. Our aim in this study is to determine the risk factors in patients with complications of the endoscopic retrograde cholangiopancreatography procedure and to determine the appropriate diagnostic and therapeutic approach in these patients. Materials and Methods: Data on 487 patients undergoing endoscopic retrograde cholangiopancreatography in 2016 were retrospectively reviewed. Results: A total of 487 patients underwent endoscopic retrograde cholangiopancreatography, 304 (62.4%) women and 183 (37.6%) men. The mean age was 61.53 (range: 18-99) years. Post-endoscopic retrograde cholangiopancreatography complications occurred in 53 (10.8%) patients; 37 (7.6%) reported pancreatitis; 15 (3.1%), bleeding; and 1 (0.2%), duodenal perforation. Post-endoscopic retrograde cholangiopancreatography improved in 2/67 (2.9%) cases with needle knife pre-cut sphincterotomy and did not develop in cases of standard sphincterotomy 65/420 (8.33%). Post- endoscopic retrograde cholangiopancreatography was less frequent in pre-cut sphincterotomy constructs, but the difference was not statistically significant (p=0.127). When the number of endoscopic retrograde cholangiopancreatography and post-ERCP cases who developed pancreatitis was compared, post-endoscopic retrograde cholangiopancreatography pancreatitis was significantly more frequent for the first time endoscopic retrograde cholangiopancreatography applied (91%) (p=0.041). Mortality was not observed in post-ERCP pancreatitis. Conclusion: Post-endoscopic retrograde cholangiopancreatography pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography. Although serious complications can be seen with endoscopic retrograde cholangiopancreatography, the technique should be used with the appropriate indications, and early identification of complications is the most important step in preventing morbidity and mortality.
    Type of Medium: Online Resource
    ISSN: 1302-5422
    Language: Unknown
    Publisher: Endoscopy Gastrointestinal
    Publication Date: 2018
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  • 4
    Online Resource
    Online Resource
    Endoscopy Gastrointestinal ; 2017
    In:  Endoskopi Gastrointestinal Vol. 24, No. 3 ( 2017-01-02), p. 73-77
    In: Endoskopi Gastrointestinal, Endoscopy Gastrointestinal, Vol. 24, No. 3 ( 2017-01-02), p. 73-77
    Abstract: Background and Aims: Diverticulosis is a very common condition. While most patients have asymptomatic diverticulosis, around one in five develops symptomatic diverticular disease. The development of diverticulosis is rare in youth, an increase in age being a major risk factor for the development of diverticulosis. Diverticula are found in more than one-half of adults over the age of 65 years. In this study, we aimed to investigate the clinical and laboratory features of geriatric patients who developed diverticulosis and to compare them to subjects with no diverticula. Materials and Methods: This retrospective case-control study included subjects aged over 65 years who underwent a colonoscopy in the period of 2011-2016 for an indication of colorectal cancer screening. Patients with diverticulosis as detected by a colonoscopy were compared to patients without diverticulosis. The comparison parameters included demographic data, comorbidities, and laboratory parameters, including a complete blood count, blood biochemistry, erythrocyte sedimentation rate, and C-reactive protein.Results: The study included 175 patients with diverticulosis whose age and sex matched 175 patients without diverticulosis. The mean age was 75.3±5.6 years in the diverticulosis group and 74.2±6.2 years in the control group. Females comprised 37% of the diverticulosis group and 42% of the control group. Diverticula were predominantly left-sided in 53%, right-sided in 9%, and bilateral in 38%. There was no difference between the groups in terms of the presence of hy- pertension, diabetes mellitus, and hyperlipidemia. The median erythrocyte sedimentation rate was higher in the diverticulosis group than in the control group (21 mm/hour (2-67) vs 17 mm/hour (3-59), p=0.03). We could not detect any difference between the groups in terms of C-reactive protein [4 mg/L (0.3-75) vs 3.5 mg/L (1.1-43.5), p=0.71] . The only biochemical parameter that was different between the groups was creatinine. The median creatinine was higher [0.90 mg/dL (0.32-2.16)] in the diverticulosis group when compared to the control group [0.82 mg/dL (0.37-2.41)] (p=0.005). Conclusions: Contrary to previous studies, we could not detect a higher prevalence of hypertension in patients with diverticulosis when compared to control subjects in this study. Our findings suggest that higher creatinine values in patients with diverticulosis may not be associated with a renal impairment in the geriatric population; instead, it may be related to obesity, which is a well-known factor for the development of diverticulosis. Obesity in adulthood may relatively contribute to protein-energy malnutrition and sarcopenia in those of an advanced age. A higher erythrocyte sedimentation rate may be an indirect marker of the ongoing low-grade inflammation in geriatric patients with diverticulosis.
    Type of Medium: Online Resource
    ISSN: 1302-5422
    Language: Unknown
    Publisher: Endoscopy Gastrointestinal
    Publication Date: 2017
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