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  • Springer  (3)
  • Elsevier  (1)
  • Jena  (1)
  • Köln : Universität zu Köln, Medizinische Fakultät, Experimentelle Pädiatrische Onkologie  (1)
  • 1
    Keywords: Forschungsbericht ; Biogasanlage ; Fermentation ; Schallwelle
    Type of Medium: Online Resource
    Pages: Online-Ressource (34 S., 414 KB) , Ill., graph. Darst.
    Language: German
    Note: Förderkennzeichen BMELV 22015211. - Verbund-Nr. 01099425 , Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden , Systemvoraussetzungen: Acrobat reader.
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  • 2
    Keywords: Forschungsbericht ; Neuroblastom ; Kind ; Systemmedizin ; Molekulare Medizin ; Ras ; Telomerase ; Genanalyse
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (11 Seiten, 120,23 KB) , Diagramme
    Language: German
    Note: Förderkenneichen BMBF 01ZX1607D , Verbundnummer 01178522 , Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden , Sprache der Zusammenfassung: Deutsch, Englisch
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Der Hautarzt 51 (2000), S. 147-151 
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Vulvodynie ; Klinische Subtypen ; Dermatosen der Vulva ; Differentialdiagnose ; Key words Vulvodynia ; Clinical subtypes ; Vulvar dermatoses ; Differential diagnoses
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Vulvodynia is a complex syndrome of chronic vulvar pain. It is divided into several subtypes: 1. cyclic vulvovaginitis (pain occurs after coitus), 2. vulvar vestibulitis syndrome (pain mainly with intercourse), 3. dysaesthetic vulvodynia (psychosomatic; diagnosis of exclusion), 4. vulvar dermatoses (e.g. pemphigus vulgaris, contact dermatitis). Additional causes have been described in single cases. Though vulvodynia is often accompanied by psychological distress, somatic causes have to be considered in each case.
    Notes: Zusammenfassung Der Begriff Vulvodynie beschreibt chronische Schmerzzustände des äußeren weiblichen Genitales. Klinisch werden verschiedene Subtypen unterschieden: 1. Zyklische Vulvovaginitis mit postkoitalem Beschwerdemaximum und fraglicher Assoziation mit Candida albicans. 2. Vulvavestibulitis mit umschriebener Schmerzhaftigkeit des Introitus durch Entzündung der dortigen Drüsenausführungsgänge mit koitalem Beschwerdemaximum. 3. Essentielle Vulvodynie als funktionelles Beschwerdebild ohne erkennbare somatische Ursache. 4. Dermatosen der Vulva unterschiedlicher Genese, wobei Autoimmunerkrankungen (z.B. Pemphigus vulgaris) und Kontaktdermatitiden von besonderer Bedeutung sind. Zusätzlich kommen verschiedene meist kasuistisch dargestellte seltene Ursachen in Betracht. Somatoforme Störungen oder psychische Alterationen können die Differentialdiagnose einer somatischen Ursache der Vulvodynie (z.B. Kontaktdermatitis) verschleiern. Ein interdisziplinäres Vorgehen ist in jedem Fall sinnvoll.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Der Hautarzt 50 (1999), S. 507-510 
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Morphaea ; Radiotherapie ; Radioderm ; Mukophanerose ; Key words Morphoea ; Radiotherapy ; Radiodermatitis ; Mucophanerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Although the aetiology of morphea often remains unknown, various precipitating causes have been identified. Morphea is a rare development following irradiation. We observed a circumscribed scleroderma 14 years after x-ray-radiotherapy following surgery of breast cancer. Furthermore multiple weeping papules occured within the radiation area. A relapse of the breast cancer was ruled out by histological examination which displayed a transepidermal elimination of acid mucin. The irradiation had obviously induced different reactions of the dermal fibroblasts (radiodermatitis, morphea, mucin production).
    Notes: Zusammenfassung Hinsichtlich der Ätiologie der Morphaea sind verschiedene chemische, physikalische und mikrobielle Auslöser bekannt. Zu den seltenen Triggerfaktoren gehören Röntgenstrahlen. Wir beobachteten eine strahleninduzierte zirkumskripte Sklerodermie 14 Jahre nach einer Röntgentiefenbestrahlung wegen eines Mammakarzinoms. Zusätzlich bestand eine transepidermale Elimination saurer Muzine, die zunächst als Papulovesikel mit schleimiger Exsudation imponierten und klinisch den Verdacht auf ein Brustwandrezidiv des Mammakarzinoms im Sinne einer tumorbedingten superfiziellen Lymphangiektasie ergaben. Die Bestrahlung führte zu einer regionalen und gleichzeitig bestehenden chronischen Radiodermatitis, Morphaea und papulösen Muzinose.
    Type of Medium: Electronic Resource
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  • 5
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    Elsevier
    In:  Biosensors and Bioelectronics, 33 (1). pp. 172-178.
    Publication Date: 2019-09-23
    Description: Detecting changes in the formation dynamics of biofilms stemming from bacteria and unicellular microorganisms in their natural environment is of prime interest for biological, ecological as well as anti-fouling technology research. We developed a robust optical fiber-based biofilm sensor ready to be applied in natural aquatic environments for on-line, in situ and non-destructive monitoring of large-area biofilms. The device is based on the detection of the natural fluorescence of microorganisms constituting the biofilm. Basically, the intrinsic fluorescence of the amino acid tryptophan is excited at a wavelength of λ=280 nm and detected at λ=350 nm utilising a numerically optimized sensor head equipped with a UV-LED light source and optical fiber bundles for efficient fluorescence light collection. Calibration was carried out with tryptophan solutions and two characteristic marine bacteria strains revealing linear signal response, satisfactory background suppression, wide dynamic range, and an experimental detection limit of 4 × 10(3)cells/cm(2). Successful field experiments in the Baltic Sea accomplished over a period of twenty-one days provided for the first time continuous observation of biofilm formation dynamics in a natural habitat. Starting from the first adhering bacteria, the measurement yielded the characteristic three phases of biofilm formation up to a fully developed biofilm. The sensor system holds potential for applications in aquatic sciences including deep sea research and, after further miniaturisation, in the industrial and biomedical field.
    Type: Article , PeerReviewed
    Format: text
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  • 6
    Publication Date: 2019-09-23
    Description: In a series of observing system simulations, we test whether the Atlantic meridional overturning circulation (AMOC) can be observed based on the existing Line W deep western boundary array. We simulate a Line W array, which is extended to the surface and to the east to cover the basin to the Bermuda Rise. In the analyzed ocean circulation model ORCA025, such an extended Line W array captures the main characteristics of the western boundary current. Potential trans-basin observing systems for the AMOC are tested by combining the extended Line W array with a mid-ocean transport estimate obtained from thermal wind "measurements" and Ekman transport to the total AMOC (similarly to Hirschi et al., Geophys Res Lett 30(7):1413, 2003). First, we close Line W zonally supplementing the western boundary array with several "moorings" in the basin (Line W-32A degrees N). Second, we supplement the western boundary array with a combination of observations at Bermuda and the eastern part of the RAPID array at 26A degrees N (Line W-B-RAPID). Both, a small number of density profiles across the basin and also only sampling the eastern and western boundary, capture the variability of the AMOC at Line W-32A degrees N and Line W-B-RAPID. In the analyzed model, the AMOC variability at both Line W-32A degrees N and Line W-B-RAPID is dominated by the western boundary current variability. Away from the western boundary, the mid-ocean transport (east of Bermuda) shows no significant relation between the two Line W-based sections and 26A degrees N. Hence, a Line W-based AMOC estimate could yield an estimate of the meridional transport that is independent of the 26A degrees N RAPID estimate. The model-based observing system simulations presented here provide support for the use of Line W as a cornerstone for a trans-basin AMOC observing system.
    Type: Article , PeerReviewed , info:eu-repo/semantics/article
    Format: text
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