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  • 1
    In: Pediatrician (St. Petersburg), ECO-Vector LLC, Vol. 7, No. 3 ( 2016-09-15), p. 84-91
    Abstract: Goal: to develop mobile application for patients with kidney stone for compliance maintenance and possible reduction of recurrence rate. Material and methods. Existing mobile applications for urolithiasis were meticulously reviewed by three groups of doctors each from different urological facilities from Saint Petersburg, Russia. Information used in our mobile application was from main urolithiasis guidelines of different urological associations. Direct application development was done by professional programmers. After application release urologist from all over the Russia were questioned about the usefulness of this product. Results. As a result of combined work application “Urolithiasis: patient assistant” was produced. Among 102 respondents 96 % evaluated this application as very useful, 3 % as useful and only 1 % considered it as a weak tool. Conclusion. Application “Urolithiasis: patient assistant” being first and single in Russian language consists of tools for compliance maintenance and plenty of other useful information regarding recurrence risk reduction and thus may be used in patients with kidney stones.
    Type of Medium: Online Resource
    ISSN: 2587-6252 , 2079-7850
    URL: Issue
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2016
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  • 2
    In: Urology reports (St. - Petersburg), ECO-Vector LLC, Vol. 10, No. 4 ( 2020-12-15), p. 293-300
    Abstract: The analysis of the results of microbiological examination of urine samples of 1022 patients (559 women and 463 men) who were hospitalized at the urological clinic of the I.P. Pavlov First Saint Petersburg State Medical University in period from 2018 to 2020 was performed. The age of the patients varied from 18 to 88 years (average 63.1 17.6 years). In 587 (57.5%) patients, gram-negative microflora was detected, in 355 (34.7%) gram-positive microflora, and in 80 (7.8%) mixed microflora. Escherichia coli (28.2%), Enterococcus faecalis (20.9%), Klebsiella pneumoniae (14.1%) and bacteria of the Staphylococcaceae family (11.6%) were prevailed in the structure of uropathogens. The share of other microorganisms did not exceed 5%. A high level of microflora resistance to ampicillin, cephalosporins of the 2nd and 3rd generations, fluoroquinolones was noted. The highest level of antibiotic resistance was observed in K. pneumonia. In general the results obtained correspond to the general trends in the dynamics of the etiological structure and the level of antibiotic resistance of nosocomial urinary tract infections. This study confirms the need for local microbiological monitoring to develop optimal regimens for empiric antibiotic therapy and perioperative antibiotic prophylaxis.
    Type of Medium: Online Resource
    ISSN: 2687-1416 , 2225-9074
    URL: Issue
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2020
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  • 3
    In: Pediatrician (St. Petersburg), ECO-Vector LLC, Vol. 8, No. 1 ( 2017-03-15), p. 95-105
    Abstract: The essence of Urolithiasis - one of the oldest diseases known by the mankind - is still not understood completely. For a long time the comprehension of Urolithiasis was based on matrix, colloid, ionic, inhibitory and precipitation theories. In these cases it was impossible to single out separate pathogenetic patterns. Besides, in spite of the absence of in vivo proofs the fact that new concrement nucleus forming (de novo nucleation) is only possible outside of the stone-forming metastability range should be taken into consideration for metaphilactic purposes. Fortunately, certain progress in understanding Urolithiasis started with the onset of studies devoted to detailed scrutiny of stone-forming patients’ metabolic peculiarities as well as with the introduction into clinical practice of the up-to-date digital endoscopes. Based on existing publications one may classify pathogenesis of stone-forming into 4 major groups: growth of calcium-oxalic stones on Randall’s plaques in patients with hypercalciumuria; excrescences on the of Belliny’s ducts’ “gags”; microlites forming within the internal medullar layer discharging tubules’ lumen in patients with cystineuria; stones forming in free solution. There is no doubt this classification is not the final one, neither does it exclude mixed variants, however better understanding of the aforementioned pathogenic variants would facilitate a novel view at Urolithiasis and in patients with kidney stones would increase anti-relapse measures’ effectiveness.
    Type of Medium: Online Resource
    ISSN: 2587-6252 , 2079-7850
    URL: Issue
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2017
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  • 4
    In: Pediatrician (St. Petersburg), ECO-Vector LLC, Vol. 8, No. 5 ( 2017-12-15), p. 61-66
    Abstract: The lack of standards in the analysis of the chemical composition of the staghorn stones leads to a decrease in the effectiveness of metaphylaxis, and especially in those cases where the volume of the stone is much larger than the volume of the stone fragment being studied. The aim of this study was to develop standards in order to determine the composition of the staghorn calculi. In the Institute of urology from 2015 to 2016, we identified patients with urolithiasis, staghorn-stone nephrolithiasis who were eventually hospitalized. All patients underwent percutaneous nephrolithotripsy, and fragments of the stone were taken in order to analyze its chemical composition. An analysis of the composition of various fragments taken from different zones of the same calculus was made. Patients were divided into 4 groups depending on the composition of the stone. The first group included patients with a predominance of phosphate in the internal layer of the pelvic fragment of the stone, the second group – with a predominance of oxalates, the third – with a predominance of urates, the fourth – with cystine stones. Our experience, while doing stone analysis, showed that the composition did not coincide in 77% of cases, and in 41,6% of cases a new component in the chemical composition of the stone appeared. Complete coincidence of the composition in the cortical and internal layer of the stone was detected in 35% of the cases, and component coincidence in 58% of cases. In the cortical and internal layers of the pelvic fragments, the total and component coincidence of the composition was 38% and 58%, respectively. Thus, we show the importance of chemical analysis of stones and that the composition of the stone may vary, depending on its location. Timely detection of changes in the nature of the stone allows an adequate treatment of urolithiasis.
    Type of Medium: Online Resource
    ISSN: 2587-6252 , 2079-7850
    URL: Issue
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2017
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  • 5
    In: Pediatrician (St. Petersburg), ECO-Vector LLC, Vol. 7, No. 4 ( 2016-12-15), p. 113-118
    Abstract: The goal of the study was to assess the level of postoperative pain in patients undergoing PCNL after paratubal infiltration with local anesthetic to compare this method of anesthesia with a control group where local anesthesia was not provided. 63 patients were included with kidney stones, confirmed by computer tomography (CT), who were planned to undergo percutaneous nephrolithitomy (PСNL). During the observation 6 patients have been excluded in accordance with the exclusion criteria. The remaining 57 patients were randomized into 2 groups: group A (n= 28) at the end of the operation received paratubal infiltration of 0.5% sol. ropivacaine; group B (n= 29) (controls) — local anesthesia was not used. Postoperative pain was assessed by means of VAS-score 1 hour, 6 hours and 24 hours after surgery. Systemic analgesia was performed with NSAIDs (intramuscular injection of 100 mg ketoprofen) when requested by the patient (Patient-Controlled Analgesia). In patients with local anesthesia, the total VAS score evaluated after 1 and 6 hours after the operation was significantly lower than in the control group. The average amount of ketoprofen required for postoperative analgesia in the group of patients with paratubal infiltration was significantly lower than in the control group. Paratubal infiltration of local anesthetic after PCNL significantly reduced postoperative pain and tended to reduce the amount of NSAIDs to eliminate pain, which in turn may reduce the risk of complications associated with NSAID.
    Type of Medium: Online Resource
    ISSN: 2587-6252 , 2079-7850
    URL: Issue
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2016
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