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  • 1
    Online Resource
    Online Resource
    Chicago :Microcosm Publishing LLC,
    Keywords: Fungi--Handbooks, manuals, etc. ; Handbooks and manuals. ; Mushrooms--Handbooks, manuals, etc. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (344 pages)
    Edition: 1st ed.
    ISBN: 9781648410499
    DDC: 579
    Language: English
    Note: Intro -- The Mycocultural Revolution -- FOREWARD by Robert Rogers, RH (AHG) -- PREFACE -- INTRODUCTION: Mycoculture Rising -- PART 1: The Past Is Myceliated -- Chapter 1: Foraging Forever -- Chapter 2: Umami, That Tastes Good! -- Chapter 3: Grand Chemists, Great Healers -- PART 2: SPAWNING THE PRESENT -- Chapter 4: Grow Your Own Mushrooms, For Everybody! -- Chapter 5: The Language of a Mycofolk -- PART 3: A FUTURE FOR FUNGI -- Chapter 6: The Mushroom Garden -- Chapter 7: A Mycocultural Revolution -- Appendix A: Species Profiles -- Appendix B: Suppliers and Online Resources -- Appendix C: Helpful Conversion Ratios -- GLOSSARY -- About the Author.
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  • 2
    Publication Date: 2012-01-12
    Description: The bacterial luciferase gene cassette (lux) is unique among bioluminescent bioreporter systems due to its ability to synthesize and/or scavenge all of the substrate compounds required for its production of light. As a result, the lux system has the unique ability to autonomously produce a luminescent signal, either continuously or in response to the presence of a specific trigger, across a wide array of organismal hosts. While originally employed extensively as a bacterial bioreporter system for the detection of specific chemical signals in environmental samples, the use of lux as a bioreporter technology has continuously expanded over the last 30 years to include expression in eukaryotic cells such as Saccharomyces cerevisiae and even human cell lines as well. Under these conditions, the lux system has been developed for use as a biomedical detection tool for toxicity screening and visualization of tumors in small animal models. As the technologies for lux signal detection continue to improve, it is poised to become one of the first fully implantable detection systems for intra-organismal optical detection through direct marriage to an implantable photon-detecting digital chip. This review presents the basic biochemical background that allows the lux system to continuously autobioluminesce and highlights the important milestones in the use of lux-based bioreporters as they have evolved from chemical detection platforms in prokaryotic bacteria to rodent-based tumorigenesis study targets. In addition, the future of lux imaging using integrated circuit microluminometry to image directly within a living host in real-time will be introduced and its role in the development of dose/response therapeutic systems will be highlighted.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Published by MDPI Publishing
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